Simultaneous search of multiple groups of antibiotics and their different components in the honey

Year 2019, Volume: 1 Issue: 1, 15 - 33, 30.08.2019

Namık Bilici , Yılmaz Altuner , Erol Kabil , Hatice Kübra Koç Topçuoğlu Ümit Topçuoğlu

Abstract

The honey is a bee (Apis
mellifera) product formed by the chemical change of the nectars that the bees
collect from the flowers. Honey is more or less affected by the antibiotics
used in bee diseases. This contagion has vital importance in terms of public
health. For this reason, simultaneous and rapid detection of different
antibiotic groups in the remnants of used veterinary medications is important.
Simultaneous identification of different groups of antibiotics depends on the
detection method of each group, the performances of the devices, and the
success of the validation. This study was carried out to realize the
identification, validation and method development of the multiplex-group
antibiotic residues, in the direction of EU Directive 2002/657 EEC. A different
method has been developed for a total of 35 antibiotics from many groups, and
the detection limits, deviations, LOD, LOQ and validations are presented. It
has been identified in this study that the simultaneous detection and
validation of multiplex-groups of antibiotics, which have not yet been
routinely practised, is possible. With this study, a unique method and a
validation technique, which may be used by national competent authorities, has
been developed.

Keywords

Honey, Residue, Antibiotic, Honeybee

Supporting Institution

Karabük Üniversitesi

Project Number

KBU-BAP-15/1-KP-037

Thanks

Acknowledgement: This study was supported by Karabük University Scientific Research Projects Unit with the number of KBU-BAP-15/1-KP-037. I would like to thank Karabük University for their support and following this tough and long-lasting process together with me.

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