Amaç: Primer enürezis nokturnalı hastalarda, hasta profilimiz ve tedavi sonuçlarının değerlendirilmesi.Gereç ve Yöntemler: Primer enürezis nokturna tanısıyla Ocak 2013-Ocak 2016 tarihleri arasında polikliniğimize başvuran ve tedavi uygulanan 5 yaş üstü toplam 540 hastadan tedaviye devam eden 324 hasta çalışmaya dâhil edildi. Daha önce bilgilendirilmemiş 56 hastaya önce 1 aylık motivasyon ve davranışa dayalı tedavi uygulandı. Davranış ve motivasyon tedavisi istemeyen, davranış ve motivasyon tedavisinden fayda görmeyen veya nüks gelişen toplam 324 hastaya, desmopressin 60-120 mikrogram uygulandı. Hastaların başvuru sırasındaki gece ıslatma sayısının %90 üzerinde azalması tam yanıt, %50-90 azalması orta derecede yanıt, %50’nin altında azalması yanıtsız olarak kabul edildi. Hastaların kontrollerinde, tedaviye tam devam edenlerde alınan yanıta göre kür ve nüks oranları değerlendirildi.Bulgular: Sadece davranış ve motivasyon tedavisi verilen ve nüks gelişmeyen 8 hasta dışında çalışmaya dâhil edilen 324 hastanın ortalama yaşı 10.57±2.37 (minimum 5- maksimum 18) olarak saptandı. Tek başına davranış ve motivasyon tedavisinden fayda görmeyen ve 120 mikrogram desmopressin tedavisi alarak kontrole gelen 166 (%51.2) hastada tam kuruluk sağlandı. Hastaların 107’sinde (%33.3) orta derecede yanıt elde edildi. Hastaların 51’inden (%15.5) ise yanıt alınamadı. Yanıt alınan hastalarda desmopressin tedavisi kesilince 45 hastada (%27.1) nüks gözlendi. Tedaviye cevap vermeyen ve ilaç dozu artırılan 4 hastada baş ağrısı ve alerji nedeniyle tedaviye devam edilemedi.Sonuç: Hastanemizin bölgesel konumu itibariyle, hastaların hastaneye başvuru yaşının daha yüksek olduğunu gözlemledik. Yine bu temel sebepten kaynaklanan ve tedavi aşamasında ilk basamak olarak düşünülen; hastanın bilgilendirilmesi, davranış ve motivasyon tedavisinin aile yakınlarını pek tatmin etmediği, tedavide yüksek başarı beklentisinden dolayı medikal tedavi ile kombine kullanılması daha fazla gerçekleşmiştir. Medikal tedavi başarı oranının genel ortalamadan düşük olmasının; tedaviye devam etmede zorluklar ve bilinçsiz ilaç kullanımı nedeniyle olduğunu düşünmekteyiz.
Objective: Evaluation of our primary nocturnal enuresis patients’ profile and their treatment outcome.Material and Methods: We included 324 of the 540 patients aged over 5 years who had applied to our outpatients between January 2013 and January 2016 and were treated for primary nocturnal enuresis. Fifty-six patients who had not received relevant information before were treated for one month with behavioral and motivational therapy. A total of 324 patients who did not benefit from this behavioral and motivational therapy or who showed relapse were started on desmopressin at a dose of 60-120 micrograms. “Full response” was defined as a decrease of 90-100% in the number of wetting instances, “moderate response” as a decrease of 50-90%, and “failed response” as a decrease of less than 50%. Treatment and relapse rates were evaluated based on the response to therapy at the time of follow-up. results: The mean age was 10.57±2.37 (minimum 5 maximum 18) years, except the 8 patients who were treated with behavioral and motivational therapy and had no relapse. Full dryness was provided in 166 (51.2%) of the patients who did not have benefit from the behavioral and motivational therapy by itself and used 120 micrograms Desmopressin. “Moderate response” was obtained in 107 (33.3%) patients. “Failed response” was obtained in 51 (15.5%) patients. Relapse was seen in case of discontinuing Desmopressin in 45 (27.1%) patients who had benefited from Desmopressin. Treatment could not proceed in 4 patients who did not respond because of headache and allergy
Other ID | JA36FJ98VV |
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Journal Section | Research Article |
Authors | |
Publication Date | December 1, 2017 |
Submission Date | December 1, 2017 |
Published in Issue | Year 2017 Volume: 11 Issue: 4 |
The publication language of Turkish Journal of Pediatric Disease is English.
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