Relationship Between the Severity of Acute Pancreatitis and Vitamin D Level in Geriatric Patient Population

Year 2023, , 519 - 526, 30.09.2023

Mercan Taştemur , Çağla Özdemir , İbrahim Akdağ

https://doi.org/10.18663/tjcl.1342760

Abstract

Background: It is important to determine the severity of acute pancreatitis (AP) and its prognosis.The aim of this study is to research the efficiency of vitamin D level on the severity of acute pancreatitis in geriatric population.
Methods: Files of 4108 patients were analyzed retrospectively. Serum vitamin D levels of total 404 patients (geriatric 160 (n:160); non-geriatric 244 (n:244)) were compared between mild, moderate and severe groups according to revised Atlanta classification for acute pancreatitis. Relationship between the severity of acute pancreatitis and vitamin D levels were analyzed.
Results: No significant difference was observed in non-geriatric patients in terms of vitamin D levels according to the Atlanta classification for acute pancreatitis. However, there were significant differences both between mild and moderate groups and between moderate and severe groups in geriatric patients (p<0.005). AP was more severe in patients with a low vitamin D level (p<0.005).
Conclusion:We have concluded that vitamin D levels may be insufficient to predict the severity of acute pancreatitis considering age factor, which is a substantial indicator of its prognosis. Vitamin D levels have been found out to be efficient in the severity of disease in geriatric acute pancreatitis patients compared to non-geriatric ones.

Keywords

Acute pancreatitis, vitamin d, prognosis, geriatric patients.

Geriatrik Hasta Popülasyonunda Akut Pankreatit Şiddeti ile D Vitamini Düzeyi Arasındaki İlişki

Abstract

Giriş: Akut pankreatitin (AP) şiddetini ve prognozunu belirlemek önemlidir. Bu çalışmanın amacı geriatrik popülasyonda D vitamini düzeyinin akut pankreatitin şiddeti üzerindeki etkinliğini araştırmaktır.
Gereç ve Yöntemler: 4108 hastanın dosyaları retrospektif olarak analiz edildi. Toplam 404 hastanın (geriatrik 160 (n:160); geriatrik olmayan 244 (n:244)) serum D vitamini düzeyleri akut pankreatit için revize Atlanta sınıflamasına göre hafif, orta ve şiddetli gruplar arasında karşılaştırıldı. Akut pankreatitin şiddeti ile D vitamini düzeyleri arasındaki ilişki analiz edildi.
Sonuçlar: Akut pankreatit için Atlanta sınıflamasına göre D vitamini düzeyleri açısından yaşlı olmayan hastalarda anlamlı bir fark gözlenmedi. Ancak, geriatrik hastalarda hem hafif ve orta gruplar arasında hem de orta ve şiddetli gruplar arasında anlamlı farklılıklar vardı (p<0,005). D vitamini düzeyi düşük olan hastalarda AP daha şiddetli idi (p<0,005).
Sonuç: Prognozun önemli bir göstergesi olan yaş faktörü göz önüne alındığında, D vitamini düzeylerinin akut pankreatitin şiddetini öngörmede yetersiz olabileceği sonucuna vardık. D vitamini düzeylerinin geriatrik akut pankreatit hastalarında geriatrik olmayanlara kıyasla hastalığın ciddiyetinde etkili olduğu bulunmuştur.

Keywords

Akut Pankreatit, d vitamini, prognoz, geriatrik hastalar.

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