Research Article
BibTex RIS Cite

Evaluation of scoring systems in predicting mortality in Fournier gangrene

Year 2019, , 230 - 234, 12.06.2019
https://doi.org/10.18663/tjcl.542072

Abstract

Aim: We
aimed to evaluate the scoring systems in predicting severity and mortality in
patients with Fournier gangrene.

Material and Methods: Demographic,
clinical and laboratory data of 76 patients included in the study were
retrospectively analyzed. Demographic characteristics, clinical and laboratory
parameters including FGSI, UFGSI and NFS scores were calculated for each
patient. ROC analysis of the scores was performed. P <0.05 was considered
statistically significant.

Results: Of
the 76 patients included in the study, 65 (85.5%) were discharged and 11
(14.5%) had mortality. All patients were divided into two groups: Group-1:
Discharged patients and Group-2: Mortality. In ROC (receiver operating
characteristic) analysis, AUC (Area Under The Curve) for FGSI, UFGSI and NFS
scores was 0.890 (95% CI: 0.785-0.994, p = 0.000), 0.895 (95% CI: 0.810-,
respectively). 0.981 (p = 0.000) and 0.867 (95% CI: 0.733-1, p = 0.000).







Conclusion: An ideal scoring system; to better understand
this disease, to identify errors in unexpected situations and mortality should
aim to be able to contribute to survival. We believe that NFS is a scoring
system with simple, easy-to-evaluate parameters and may be very useful in
assessing mortality in clinical practice.

References

  • 1. Corman J, Moody J, Aronson W. Fournier's gangrene in a modern surgical setting: improved survival with aggressive management. BJU international 1999; 84: 85-88.
  • 2. Paty R, Smith A. Gangrene and Fournier's gangrene. The Urologic clinics of North America 1992; 19: 149- 62.
  • 3. Luther Ward M, Eisenson D, Fils J-L. Fournier's gangrene of the penis in a 12-year-old patient secondary to phimosis. Rhode Island Medical Journal 2016; 99: 45.
  • 4. Benjelloun EB, Souiki T, Yakla N et al. Fournier’s gangrene: our experience with 50 patients and analysis of factors affecting mortality. World Journal of Emergency Surgery 2013; 8: 13.
  • 5. Morua AG, Lopez J, Garcia J, Montelongo RM, Guerra L. Fournier’s gangrene: our experience in 5 years, bibliographic review and assessment of the Fournier’s gangrene severity index. Arch Esp Urol 2009; 62: 532-40.
  • 6. Erdoğan A, Aydoğan İ, Şenol K, Üçkan E, Ersöz Ş, Tez M. Simple scoring system for prediction of mortality in Fournier’s gangrene. European Journal of Trauma and Emergency Surgery 2016; 42: 513-18.
  • 7. Eke N. Fournier's gangrene: A review of 1726 cases. British Journal of Surgery. 2000; 87: 718-28.
  • 8.Küçükdurmaz F. Fournier gangreninde mortaliteyi etkileyen faktörlerin değerlendirilmesi: 38 hastalık deneyimimiz. Yeni Üroloji Dergisi 2016; 12: 29-34.
  • 9. Tarchouli M, Bounaim A, Essarghini M et al. Analysis of prognostic factors affecting mortality in Fournier’s gangrene: A study of 72 cases. Canadian Urological Association Journal 2015; 9: 800.
  • 10. Sorensen MD, Krieger JN, Rivara FP, Klein MB, Wessells H. Fournier's gangrene: management and mortality predictors in a population based study. The Journal of urology 2009; 182: 2742-47.
  • 11. Yilmazlar T, Ozturk E, Ozguc H, Ercan I, Vuruskan H, Oktay B. Fournier’s gangrene: an analysis of 80 patients and a novel scoring system. Techniques in coloproctology 2010; 14: 217-23.
  • 12. Laor E, Palmer LS, Tolia BM, Reid RE, Winter HI. Outcome prediction in patients with Fournier's gangrene. The Journal of urology 1995; 154: 89-92.
  • 13. Dahm P, Roland FH, Vaslef SN et al. Outcome analysis in patients with primary necrotizing fasciitis of the male genitalia. Urology 2000; 56: 31-35.
  • 14. Yılmazlar T, Işık Ö, Öztürk E, Özer A, Gülcü B, Ercan İ. Fournier’s gangrene: review of 120 patients and predictors of mortality. Ulus Travma Acil Cerrahi Derg. 2014; 20: 333-37.
  • 15. Erol B, Tuncel A, Hanci V et al. Fournier's gangrene: overview of prognostic factors and definition of new prognostic parameter. Urology 2010; 75: 1193-98.
  • 16. Janane A, Hajji F, Ismail T et al. Hyperbaric oxygen therapy adjunctive to surgical debridement in management of Fournier's gangrene: Usefulness of a severity index score in predicting disease gravity and patient survival. Actas Urológicas Españolas (English Edition) 2011; 35: 332-38.

Fournier gangreninde mortaliteyi öngörmede skorlama sistemlerinin değerlendirilmesi

Year 2019, , 230 - 234, 12.06.2019
https://doi.org/10.18663/tjcl.542072

Abstract

Amaç: Fournier gangreni hastalarında şiddet ve mortaliteyi
öngörmede skorlama sistemlerini değerlendirmeyi amaçladık.

Gereç ve Yöntemler: Çalışmaya
dahil edilen 76 hastanın demografik,
klinik ve laboratuvar verileri elektronik ortamda retrospektif olarak
incelendi. Çalışmada her hasta için demografik özellikleri, klinik ve laboratuvar
parametrelerini içeren FGSI, UFGSI ve NFS skorları hesaplandı. Skorların ROC
analizi yapıldı. Analizimiz sonucunda p<0,05 olanlar istatistiksel olarak
anlamlı kabul edildi.

Bulgular: Çalışmaya
dahil edilen 76 hastanın 65(%85,5)’i taburcu edilirken, 11(%14,5)’inde
mortalite gelişti. Tüm hastalar, Grup-1: Taburcu edilen hastalar ve Grup-2:
Mortalite gelişenler olarak iki gruba ayrıldı. ROC((receiver operating
characteristic) analizinde; FGSI, UFGSI ve NFS skorları için AUC (Area Under
The Curve=Eğrinin Altında Kalan Alan) sırasıyla 0,890 (%95 CI: 0.785-0.994,
p=0.000), 0,895 (%95 CI: 0.810-0.981, p=0.000) ve 0,867 (%95 CI: 0.733-1, p=0.000)
olarak bulundu.







Sonuç: İdeal
bir skorlama sistemi; bu hastalığı daha iyi anlamak, beklenmedik mortalite
durumlarında hataları tanımlayabilmek ve sağkalıma katkıda bulunabilmeyi
amaçlamalıdır. NFS’nin basit, kolay değerlendirilen parametreler içeren bir
skorlama sistemi olduğunu ve klinik pratikte mortaliteyi değerlendirmede
oldukça faydalı olabileceğini düşünüyoruz.

References

  • 1. Corman J, Moody J, Aronson W. Fournier's gangrene in a modern surgical setting: improved survival with aggressive management. BJU international 1999; 84: 85-88.
  • 2. Paty R, Smith A. Gangrene and Fournier's gangrene. The Urologic clinics of North America 1992; 19: 149- 62.
  • 3. Luther Ward M, Eisenson D, Fils J-L. Fournier's gangrene of the penis in a 12-year-old patient secondary to phimosis. Rhode Island Medical Journal 2016; 99: 45.
  • 4. Benjelloun EB, Souiki T, Yakla N et al. Fournier’s gangrene: our experience with 50 patients and analysis of factors affecting mortality. World Journal of Emergency Surgery 2013; 8: 13.
  • 5. Morua AG, Lopez J, Garcia J, Montelongo RM, Guerra L. Fournier’s gangrene: our experience in 5 years, bibliographic review and assessment of the Fournier’s gangrene severity index. Arch Esp Urol 2009; 62: 532-40.
  • 6. Erdoğan A, Aydoğan İ, Şenol K, Üçkan E, Ersöz Ş, Tez M. Simple scoring system for prediction of mortality in Fournier’s gangrene. European Journal of Trauma and Emergency Surgery 2016; 42: 513-18.
  • 7. Eke N. Fournier's gangrene: A review of 1726 cases. British Journal of Surgery. 2000; 87: 718-28.
  • 8.Küçükdurmaz F. Fournier gangreninde mortaliteyi etkileyen faktörlerin değerlendirilmesi: 38 hastalık deneyimimiz. Yeni Üroloji Dergisi 2016; 12: 29-34.
  • 9. Tarchouli M, Bounaim A, Essarghini M et al. Analysis of prognostic factors affecting mortality in Fournier’s gangrene: A study of 72 cases. Canadian Urological Association Journal 2015; 9: 800.
  • 10. Sorensen MD, Krieger JN, Rivara FP, Klein MB, Wessells H. Fournier's gangrene: management and mortality predictors in a population based study. The Journal of urology 2009; 182: 2742-47.
  • 11. Yilmazlar T, Ozturk E, Ozguc H, Ercan I, Vuruskan H, Oktay B. Fournier’s gangrene: an analysis of 80 patients and a novel scoring system. Techniques in coloproctology 2010; 14: 217-23.
  • 12. Laor E, Palmer LS, Tolia BM, Reid RE, Winter HI. Outcome prediction in patients with Fournier's gangrene. The Journal of urology 1995; 154: 89-92.
  • 13. Dahm P, Roland FH, Vaslef SN et al. Outcome analysis in patients with primary necrotizing fasciitis of the male genitalia. Urology 2000; 56: 31-35.
  • 14. Yılmazlar T, Işık Ö, Öztürk E, Özer A, Gülcü B, Ercan İ. Fournier’s gangrene: review of 120 patients and predictors of mortality. Ulus Travma Acil Cerrahi Derg. 2014; 20: 333-37.
  • 15. Erol B, Tuncel A, Hanci V et al. Fournier's gangrene: overview of prognostic factors and definition of new prognostic parameter. Urology 2010; 75: 1193-98.
  • 16. Janane A, Hajji F, Ismail T et al. Hyperbaric oxygen therapy adjunctive to surgical debridement in management of Fournier's gangrene: Usefulness of a severity index score in predicting disease gravity and patient survival. Actas Urológicas Españolas (English Edition) 2011; 35: 332-38.
There are 16 citations in total.

Details

Primary Language Turkish
Subjects Health Care Administration
Journal Section Orıgınal Artıcle
Authors

Sadettin Er 0000-0003-0712-3153

Ramazan Topçu 0000-0001-6214-4868

Deniz Tikici 0000-0003-1759-2973

Sabri Özden This is me 0000-0002-7219-046X

Mesut Tez 0000-0003-4004-3948

Publication Date June 12, 2019
Published in Issue Year 2019

Cite

APA Er, S., Topçu, R., Tikici, D., Özden, S., et al. (2019). Fournier gangreninde mortaliteyi öngörmede skorlama sistemlerinin değerlendirilmesi. Turkish Journal of Clinics and Laboratory, 10(2), 230-234. https://doi.org/10.18663/tjcl.542072
AMA Er S, Topçu R, Tikici D, Özden S, Tez M. Fournier gangreninde mortaliteyi öngörmede skorlama sistemlerinin değerlendirilmesi. TJCL. June 2019;10(2):230-234. doi:10.18663/tjcl.542072
Chicago Er, Sadettin, Ramazan Topçu, Deniz Tikici, Sabri Özden, and Mesut Tez. “Fournier Gangreninde Mortaliteyi öngörmede Skorlama Sistemlerinin değerlendirilmesi”. Turkish Journal of Clinics and Laboratory 10, no. 2 (June 2019): 230-34. https://doi.org/10.18663/tjcl.542072.
EndNote Er S, Topçu R, Tikici D, Özden S, Tez M (June 1, 2019) Fournier gangreninde mortaliteyi öngörmede skorlama sistemlerinin değerlendirilmesi. Turkish Journal of Clinics and Laboratory 10 2 230–234.
IEEE S. Er, R. Topçu, D. Tikici, S. Özden, and M. Tez, “Fournier gangreninde mortaliteyi öngörmede skorlama sistemlerinin değerlendirilmesi”, TJCL, vol. 10, no. 2, pp. 230–234, 2019, doi: 10.18663/tjcl.542072.
ISNAD Er, Sadettin et al. “Fournier Gangreninde Mortaliteyi öngörmede Skorlama Sistemlerinin değerlendirilmesi”. Turkish Journal of Clinics and Laboratory 10/2 (June 2019), 230-234. https://doi.org/10.18663/tjcl.542072.
JAMA Er S, Topçu R, Tikici D, Özden S, Tez M. Fournier gangreninde mortaliteyi öngörmede skorlama sistemlerinin değerlendirilmesi. TJCL. 2019;10:230–234.
MLA Er, Sadettin et al. “Fournier Gangreninde Mortaliteyi öngörmede Skorlama Sistemlerinin değerlendirilmesi”. Turkish Journal of Clinics and Laboratory, vol. 10, no. 2, 2019, pp. 230-4, doi:10.18663/tjcl.542072.
Vancouver Er S, Topçu R, Tikici D, Özden S, Tez M. Fournier gangreninde mortaliteyi öngörmede skorlama sistemlerinin değerlendirilmesi. TJCL. 2019;10(2):230-4.


e-ISSN: 2149-8296

The content of this site is intended for health care professionals. All the published articles are distributed under the terms of

Creative Commons Attribution Licence,

which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.