The correlation between mitral annular calcification and prognostic nutritional index

Year 2019, , 452 - 458, 31.12.2019

Veysel Ozan Tanık , Hilal Erken Pamukçu

https://doi.org/10.18663/tjcl.587533

Cited By: 3

Abstract

Aim:Prior studies have established the importance
of prognostic nutritional index (PNI) in patients with colorectal cancer and ST
elevation myocardial infarction. However, the relation ship between the nutritional
status and the mitral annular calcification (MAC) has not been investigated
yet. Hence, the aim of this study was to examine the relationship between the
presence of MAC and the PNI.

Material and Methods:In total, 398 patients who were
admitted to our cardiology department were included in this retrospective analysis.
A total of 310 patients with MAC (+) constituted the study group, while 88
subjects without MAC (-) were accepted as a control group.Clinical characteristics
of the patients including age, sex, hypertension and diabetes mellitus were
retrieved from hospital electronic database. The
PNI was calculated using the following equation: 10×serum albumin (g/dL) +
0.005 × total lymphocyte count (per mm³).

Results:Serum albumin levels were found to be significantly lower in the MAC (+) group compared to the control group (3.76±0.57 vs. 4.12±0.31, p<0.001, respectively).  Total lymphocyte count of the MAC group was also significantly lower than the control group (1.86±0.63 vs. 2.02±0.66, p=0.05, respectively). Notably, the PNI of the MAC (+)group were significantly lower than the MAC (-) group (38.5 ± 5.8 vs. 42.2 ± 3.1; p <0.001, respectively). In correlation analysis, the PNI wasfoundto be negativelycorrelatedwiththepresence of MAC (r:-0.285; p<0.001).

Conclusion:We found that the presence of MAC
is significantly associated with lower levels of the PNI.

Keywords

mitral annular calcification, prognostic nutritional index, malnutrition

Mitral anüler kalsifikasyon ile prognostik nutrisyonel indeks arasındaki koreleasyon

Abstract

Amaç: Hastaların nütrisyonel
durumu ve mitral anüler kalsifikasyon (MAK) arasında ilişki daha önce herhangi
bir şekilde ortaya konulamamıştır. Daha önceki çalışmalarda prognostik nütrisyonel
indeksinin (PNİ) kolorektal kanserli hastalardaoperasyon sonrası septik
komplikasyonlar ve ST yükselmeli miyokart enfarktüsü gibi birçok hastalıkta
prognostik öneme sahip olduğu gösterilmiştir. Bu çalışmanın amacı PNİ ile MAK
varlığı arasındaki ilişkiyi ortaya koymaktır.

Gereç ve Yöntemler: Bu retrospektif çalışmaya
ekokardiyografi laboratuvarına başvuran 398 hasta dahil edildi. MAK saptanan
310 hasta ile çalışma grubu,MAK saptanmayan 88 kişi ile kontrol grubu
oluşturuldu. Kontrol grubuna; yaş,cinsiyet,hipertansiyon ve diyabetesmellitus
varlığı gibi demografik özellikler açısından, MAK (+) grupla benzer özellikler
taşıyan hastalar dahil edildi. Laboratuvar parametreleri kaydedildi ve PNİ
değerleri hesaplandı.

Bulgular: Gruplar
arasında ortalama yaş, hipertansiyon ve diyabet varlığı açısından fark mevcut
değildi. Serum albümin düzeyleri MAK (+) grupta kontrol grubuna göre
istatistiki olarak anlamlı olacak şekilde daha düşük seviyelerde saptandı (3,76±0,57;
4,12 ±0,31,p<0,001). Lenfosit sayısı MAK (+) grupta kontrol grubuna göre
sınırda düşük saptandı (1,86±0,63; 2,02 ±0,66,p =0,05)Prognostik nütrisyonel
indeks, mitral anulus kalsifikasyonu saptanan hasta grubunda kontrol grubuna
göre anlamlı olarak düşük saptandı (38,5±5,8 ; 42,2±3.1 ,p <0,001).
Prognostik nütrisyonel düzeyi mitral anulus kalsifikasyonun bulunması açısından
istatiksel olarak anlamlı ve güçlü, bağımsız bir risk faktörü olarak saptandı.

Sonuç: Çalışmamız sonuç olarak MAK
varlığı ile PNİ birbiriyle ilişkili bulmuştur. MAK pozitifliği ile düşük
seviyedeki PNİ değeri istatistiksel olarak anlamlı bir şekilde ilişkili
bulunmuştur. 

Keywords

Mitral annüler kalsifikasyon, prognostik nutrisyonel indeks

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