Nutrisyonel boy kısalığı olan adolesanlarda nutrisyonel destek tedavisinin büyüme faktörleri üzerine etkisi: uzun süreli izlem sonuçları

Year 2018, Volume: 9 Issue: 2, 126 - 130, 01.09.2018

Ayça Törel Ergür , Fatma Nişancı Kılınç , Sevinç Odabaşı Güneş , Çağlar Yörgüç Üçler Kısa

https://doi.org/10.18663/tjcl.320100

Abstract

Amaç: Uzun süreli
yetersiz nutrisyon alımı çocukluk çağında boy kazanımını negatif olarak
etkiler.  Bu çalışmanın amacı nutrisyonel
boy kısalığı (NBK) tanısı alan adolesanlarda oral nutrisyonel destek ürününün (ONDÜ)
büyüme hızı (BH) ve büyüme faktörleri (BF) üzerine olan etkisini incelemektir.

Gereç ve Yöntemler: NBK tanısı alan 16 adolesan çalışmaya dahil edildi.
Hastalar oral beslenme ile alımlarını kaydetti, kalori açıkları hesaplandı ve
açıkları ONDÜ ile tamamlandı. Nutrisyonel destek tedavisinin BH, BF ve büyüme
parametreleri üzerine etkisi 0, 6, 12. aylarda değerlendirildi.

Bulgular: Olguların 6. ve 12. aylardaki boy
kazanımları; 6. aydaki IGF-BP3 artışı; 12. aydaki IGF-1, beden kitle indeksi ve
vücut ağırlığı SDS artışı istatistiksel olarak anlanlı saptandı. (p<0.05).

Sonuç: Nutrisyonel boy kısalığı olan adolesanlara verilen uzun
sureli ONDÜ tedavisi büyüme faktörlerini arttırmaktadır. IGF-1 seviyesindeki
artış güvenli sınırlar içerisinde saptanmıştır. 

Keywords

Nutrisyon tedavisi, boy kısalığı, adolesan

The effect of nutritional support treatment on growth factors in adolescents with nutritional short stature: result of long-term follow-up

Abstract

Aim: Long-term insufficient nutrition intake in
childhood affects height gain negatively. This study was designed to analyze
the effect of oral nutritional support product (ONSP) treatment on growth
velocity (GV) and growth factors (GF) in adolescents who diagnosed as nutritional
short stature (NSS).

Material and Methods: Sixteen adolescents diagnosed as NSS were
involved. Patients recorded their dietary intake; caloric deficiencies were
calculated and fulfilled with ONSP. Effect of nutritional support treatment on
GV, GF and growth parameters were analyzed on 0^th, 6^th ,12^th 
 months.

Results: The increment of the height of the cases on 6^th and
12^th month, increment of IGFBP3 on 6^th month, the increment of IGF-1 levels, BMI and weight SDS of the
cases on 12^th month and  were statistically significant (p < 0.05).

Conclusions: Long-term ONSP treatment, which is given
to the adolescents with NSS increases the growth factors. The increment of
IGF-1 levels was in between secure limits.

Keywords

Nutrition therapy, short stature, adolescents

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