Kolorektal kanserlerin senkron karaciğer metastazları: Kombine cerrahi prosedür deneyimimiz

Year 2019, Volume: 10 Issue: 3, 310 - 313, 30.09.2019

Muhammed Raşid Aykota , Sevda Yılmaz , Uğur Sungurtekin

https://doi.org/10.18663/tjcl.555703

Abstract

Amaç:
Kolorektal kanserlerin (KRK) en sık metastaz yaptığı organ karaciğerdir ve tanı
anında hastaların yaklaşık %25’inde senkron karaciğer metastazı bulunur. Karaciğer
metastazı olan KRK hastalarında cerrahi yaklaşım hala tartışma konusudur. Her hasta için tedavi stratejisi, hastanın performans
durumuna, komorbiditelerine ve tümör aşamasına bağlı olarak
kişiselleştirilmelidir. Bu çalışmanın amacı kliniğimizde senkron
karaciğer metastazlı KRK hastalarına yönelik
tedavi yaklaşımımızı ortaya koymak ve literatürle karşılaştırmaktır.

Gereç
ve Yöntemler:
Ocak 2016 ile Aralık 2018
yılları arasında senkron karaciğer metastazlı KRK tanılı, kombine cerrahi prosedür olarak adlandırılan eş
seanslı kolorektal kanser ameliyatı ve hepatik rezeksiyon yapıldığı sekiz hasta
çalışmaya dahil edildi.

Bulgular: İki hastaya sağ hepatektomi yapılırken,
altı hastaya metastezektomi yapıldı. TNM evresine göre bir hastada (%12) T1/2,
yedi hastada (%88) T3/4 tümör saptandı. Hastaların dördünde (%50) lenf nodu
metastazı saptandı. Bir hasta post operatif  3. günde MODS nedeniyle kaybedildi.

Sonuç: Bizim çalışmamızın sonuçlarında da olduğu gibi literatürde
senkronize yaklaşım için hasta seçiminde en önemli kriterler; hasta yaşı ve
yapılan hepatik rezeksiyonun hacmi olarak bildirilmiştir. Sonuç olarak cerrahi
tedavi yaklaşım tercihinde, her merkez kendi protokollerini hasta özelliklerini
dikkate alarak multidisipliner bir şekilde belirlemelidir. 

Keywords

kolorektal kanser, karaciğer metastazı, cerrahi, cerrahi

Synchronous liver metastases of colorectal cancers: Our experience of combined surgical procedure

Abstract

Aim: The most common metastasis of colorectal cancer (CRC) is the liver
and approximately 25% of patients have synchronous liver metastases at the time
of diagnosis. Surgical management of CRC patients with liver metastasis is still
controversial. The treatment strategy for each patient should be personalized
depending on the patient's performance status, comorbidities and tumor stage.
The aim of this study was to determine our treatment approach for CRC patients
with synchronous liver metastasis in our clinic and to compare them with the
literature.

Material
and Methods: Between January 2016 and
December 2018, eight patients with synchronous liver metastatic CRC, combined
surgical procedure called co-operated colorectal cancer surgery and hepatic
resection were included in the study.

Results: Two patients underwent right hepatectomy and six patients
underwent metastasectomy. T1 / 2 tumor was detected in one patient (12%) and T3
/ 4 tumor in seven patients (88%) according to TNM stage. Four of the patients
(50%) had lymph node metastasis. One patient died on the 3rd postoperative day
due to MODS.

Conclusion: As in the results of our study, the most important criteria in
patient selection for synchronous approach in literature are; The age of the
patient and the volume of hepatic resection performed were reported. As a
result, in the choice of surgical treatment approach, each center should
determine its protocols in a multidisciplinary way considering the patient
characteristics.

Keywords

liver metastasis, colorectal cancer, liver metastasis, surgery

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