A cross‐sectional study: Is there any effects of cholesterol ratios on acute ischemic stroke severity?

Year 2019, Volume: 10 Issue: 4, 437 - 439, 31.12.2019

Bilgin Öztürk Miraç Ayşen Ünsal

https://doi.org/10.18663/tjcl.588068

Abstract

Aim: The
aim of prevention of stroke and stroke related complications is to control and
eliminate modifiable risk factors. Since hypercholesterolemia is one of these
risk factors, we aimed to compare the low density lipoprotein cholesterol
(LDL-C) / high density lipoprotein cholesterol (HDL-C) and total cholesterol /
HDL-C ratios with NIHSS scores and to evaluate the effects of these ratios on
the severity of stroke.

Material
and Methods:This retrospective cross-sectional
study included 207 patients with ischemic stroke. Demographic characteristics,
total cholesterol, triglycerides, LDL-C and HDL-C levels of patients who did
not use any lipid-lowering drug and NIHSS scores were recorded in a data
collection form.

The
effects of LDL-C / HDL-C and total cholesterol / HDL-C ratios on NIHSS scores
were investigated.
Results:The mean age of the patients
was 69.3 years. The mean LDL-C / HDL-C ratio was 2.93 and the total cholesterol
/ HDL-C ratio was 4.68. The mean score of NIHSS was 7.05 at admission. No statistically
significant difference or correlation was observed between all these
parameters.

Conclusion:There
was no statistically significant relationship between HDL-C / LDL-C and total
cholesterol / HDL-C ratios and NIHSS scores. Considering the risk of ischemic
stroke, prospective multicentric studies are needed to find proper parameters.

Keywords

ischemic stroke, HDL-C, LDL-C

Kesitsel bir araştırma: Kolesterol oranlarının akut iskemik inme şiddeti üzerine etkisi var mı?

Abstract

Amaç:İnme
ve inme ile ilgili komplikasyonların önlenmesinin amacı, değiştirilebilir risk
faktörlerini kontrol etmek ve ortadan kaldırmaktır. Hiperkolesterolemi bu risk
faktörlerinden biri olduğundan, düşük dansiteli lipoprotein kolesterol (LDL-C)
/ yüksek dansiteli lipoprotein kolesterol (HDL-C) ve total kolesterol / HDL-C
oranları ile NIHSS puanlarını karşılaştırarak, bu oranların inme ciddiyetine
etkilerini değerlendirmeyi amaçladık.

Gereç ve Yöntemler: Bu
retrospektif kesitsel araştırma iskemik inmeli 207 hastayı içermektedir.
Hastaların demografik özellikleri, total kolesterol, trigliserit, herhangi bir
lipid düşürücü ilaç kullanmayan hastaların LDL-C ve HDL-C düzeyleri ve NIHSS
skorları bir veri toplama formunda kaydedildi. LDL-C / HDL-C ve total
kolesterol / HDL-C oranlarının NIHSS puanlarına etkisi araştırıldı.

Bulgular:Hastaların
yaş ortalaması 69.3 idi. Tüm bu hastalar arasında ortalama LDL-C / HDL-C oranı
2.93 ve total kolesterol / HDL-C oranı 4.68 idi. Başvuru sırasında NIHSS'nin
ortalama puanı 7.05 idi. Tüm bu parametreler arasında istatistiksel olarak
anlamlı bir fark veya korelasyon gözlenmedi.
Sonuç:Başvuru sırasında HDL-C /
LDL-C ile total kolesterol / HDL-C oranları ve NIHSS skorları arasında
istatistiksel olarak anlamlı bir ilişki gözlenmedi. İskemik inme risklerini göz
önünde bulundurarak uygun parametreleri bulmak için ileriye dönük çok merkezli
çalışmalara ihtiyaç vardır.

Keywords

iskemik inme, HDL-C, LDL-C

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