Retrospective evaluation of the clinical and demographic characteristics of herpes zoster cases followed up in our clinic during the Covid-19 pandemic

Year 2024, Volume: 15 Issue: 1, 45 - 55, 28.03.2024

Işıl Göğem İmren , Şule Subaşı Gökşin

https://doi.org/10.18663/tjcl.1388554

Abstract

Aim: In our study, which included both pediatric and adult patients; we aimed to contribute to the follow-up of patients by evaluating the two-year demographic and clinical data of Herpes Zoster patients who were followed and treated in the dermatovenerology clinic of a secondary level hospital.
Material and Methods: In this cross-sectional study, the clinic and epidemiological records of patients who were clinically diagnosed with herpes zoster in the Denizli State Hospital Dermatovenerology outpatient clinic between October 2020 and October 2022 were evaluated retrospectively.
Results: The age range was between 2 and 94 among 289 HZ patients, and the mean age was 52.12 ±22.635 years. Fifty-three percent were female and 47 % were male. While the 18-65 age group was the most crowded group with 166 (57.43%) patients, there were 33 (11.41%) patients under the age of 18. A history of predisposing factors was found in 85.1% of the patients. Stress was detected the most common predisposing factor in adults and infections in childhood. A history of an additional systemic comorbidity was found in %69.2 of the patients, and additional dermatologic comorbidity was found in %68.1 of the patients. Complications were found in 60.2% of the patients, and 52.6% had postherpetic neuralgia. It was observed that 9% of the patients were hospitalized.
Conclusion: In our study, we determined the clinical and epidemiological data of HZ patients we followed in Denizli during the years under the influence of the COVID-19 pandemic, and the risk factors associated with HZ complications. We consider that morbidity and mortality caused by complications can be significantly reduced by informing the society about disease, vaccinating risk groups, early appointment to hospital, appropriate treatment, close follow-up and hospitalization when necessary.

Keywords

Herpes zoster, epidemiology, postherpetic neuralgia, COVID-19

Kliniğimizde Covid-19 pandemisi döneminde takip edilen herpes zoster olgularının klinik ve demografik özelliklerinin retrospektif değerlendirilmesi

Abstract

Amaç: Hem pediatrik hem de erişkin hastaları içeren çalışmamızda kliniğimizde takip ve tedavi edilen Herpes Zoster olgularının demografik ve klinik özelliklerini inceleyerek, hastaların izlemine katkı sunmayı amaçladık.
Yöntemler: Bu kesitsel çalışmada, ikinci basamak bir hastanenin Deri ve Zührevi Hastalıklar polikliniğinde, Ekim 2020-Ekim 2022 tarihleri arasında, klinik olarak herpes zoster tanısı alan hastaların klinik ve epidemiyolojik verileri retrospektif olarak değerlendirilmiştir.
Bulgular: Çalışmaya dahil edilen 289 hastanın %53’ü kadın, %47’si erkek, ortalama yaş 52.12 (±22,635), median yaş 58 (2-94) bulundu. 18-65 yaş aralığı 166 (%57,43) hasta ile en kalabalık grubu oluştururken, 18 yaş altı 33 (%11,41) hasta bulunmaktaydı. En sık tutulan bölge torakal dermatom (%37,4) olarak saptandı. Hastaların %85,1’ inde tetikleyici faktör öyküsü saptandı. Yetişkinlerde stres, çocukluk çağında ise enfeksiyonlar en sık tespit edilen tetikleyici faktörlerdi. Hastaların %69, 2 ’sinde sistemik komorbidite , %68.1’inde dermatolojik komorbidite bulunmaktaydı. En sık görülen komplikasyon postherpetik nevralji (%42.6) olmak üzere tüm hastaların %60, 2 ’sinde HZ’a dair komplikasyonlar tespit edildi. Hastaların %9’u
hospitalize edilerek tedavi edildi.
Sonuç: COVID-19 pandemisinin etkisi altındaki bu yıllarda Denizli ilinde takip ettiğimiz HZ hastalarına dair klinik ve epidemiyolojik verileri ve HZ komplikasyonları ile ilişkili risk faktörlerini belirlemeye yönelik olarak yaptığımız çalışmamızın sonucunda; toplumun HZ hastalığı hakkında bilgilendirilmesi, riski grupların aşılanması, zamanında başvuru, uygun tedavinin erken dönemde düzenlenmesi, gerekli hallerde hospitalizasyon ve yakın takip ile komplikasyonların yaratacağı morbidite ve mortalitenin belirgin ölçüde azaltılabileceğini düşünmekteyiz.

Keywords

Herpes zoster, epidemiyoloji, postherpetic nevralji, COVID-19.

Ethical Statement

Çalışma için Pamukkale Üniversitesi Girişimsel Olmayan Klinik Araştırmalar Etik kurulundan onay alındı (18.10.2022 E-60116787-020-278878). Çalışmaya katılan tüm gönüllülere çalışma hakkında bilgi verilerek aydınlatılmış onamları alındı. Çalışma Helsinki bildirgesi prensiplerine uygun bir şekilde yürütüldü.

Supporting Institution

Bu araştırma hiçbir kurum ve kuruluş tarafından finansal olarak desteklenmemiştir.

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