Çocuklarda COVID-19 sonrası streptokokal tonsillofarenjit sıklığındaki değişiklikler

Year 2024, Volume: 15 Issue: 1, 110 - 116, 28.03.2024

Yunus Nas , Süveyda Gözüküçük

https://doi.org/10.18663/tjcl.1440105

Abstract

Amaç: Koronavirus hastalığı 2019 (COVID-19) pandemisi öncesi ve sonrasında Streptococcus pyogenes (GAS) tonsillofarenjit sıklığında yaşanan değişikliklere ilişkin kapsamlı veriler yetersizdir. Bu çalışmada, COVID-19 dönemi öncesi, sırası ve sonrasında çocuklarda GAS sıklığında meydana gelen değişiklikleri incelemeyi amaçlanmıştır.
Gereç ve Yöntemler: Bu retrospektif çalışmaya, Haziran 2018 ile Haziran 2023 tarihleri arasında klinik bulgularla bakteriyel tonsillofarenjit ön tanısı alan 13,061 çocuk hasta dahil edildi. Tüm hastalara Strep A antijen testi yapılmış ve boğaz sürüntü örnekleri toplanmıştır. Hastalar, hastaneye başvuru tarihlerine göre üç gruba ayrıldı: Grup 1, COVID-19 pandemisi öncesi dönem (1 Ocak 2018 - 10 Mart 2020); Grup 2, COVID-19 pandemisi sırasında sıkı önlemlerin uygulandığı dönem (11 Mart 2020 - 30 Haziran 2021); ve Grup 3, COVID-19 pandemisi önlemlerinin kaldırıldığı dönem (1 Temmuz 2021 - 30 Haziran 2023).
Bulgular: Tüm popülasyonda GAS prevalansı %23.2 (n=3024) idi. Gruplar arasında, Grup 3 en yüksek GAS sıklığına sahipken, bunu Grup 1 ve ardından Grup 2 izledi (Grup 1: %18.1, Grup 2: %6.0, Grup 3: %29.6, p < 0.001). COVID-19 pandemisine karşı katı önlemlerin alındığı dönemde, COVID-19 öncesi döneme kıyasla GAS sıklığında önemli bir azalma gözlemlendi. Ancak, COVID-19 ile ilişkili kısıtlamaların gevşetilmesiyle, özellikle 2022'nin son çeyreği ve 2023 ilkbaharında, GAS sıklığında belirgin bir artış saptandı.
Sonuçlar: Çocuklarda, GAS sıklığı COVID-19 izolasyon önlemleriyle önemli ölçüde azaldı. Ancak, bu izolasyon önlemlerinin gevşetilmesinin ardından ani bir artış gözlemlendi.

Keywords

Grup A Beta-Hemolitik Streptokok, COVID-19, hızlı strep A testi, tonsillofarenjit

Ethical Statement

The study was performed in accordance with the Declaration of Helsinki, and was approved by the Hisar Intercontinental Hospital Ethics Committee (Date: 22.09.2023, Decision No: 23-48).

Project Number

Decision No: 23-48, Date: 22.09.2023

Variations in the frequency of streptococcal tonsillopharyngitis among children after COVID-19

Abstract

Aim: Comprehensive data on the variations in the frequency of Streptococcus pyogenes (GAS) tonsillopharyngitis before
and after the Coronavirus disease 2019 (COVID-19) pandemic are still insufficient. This study aimed to investigate the changes in the frequency of GAS in children before, during, and after the COVID-19 period.
Material and Methods: This retrospective study included 13,061 patients diagnosed with a pre-diagnosis of bacterial tonsillopharyngitis based on clinical findings, between June 2018 and June 2023. All patients were administered the Strep A antigen test, and throat swab samples were collected. Patients were divided into three groups based on their hospital admission dates. Group 1, pre-COVID-19 pandemic period (1 January 2018 – 10 March 2020); Group 2, during the COVID-19 pandemic when strict measures were enforced (11 March 2020 – 30 June 2021); and Group 3, the period after the lifting of COVID-19 pandemic measures (1 July 2021 – 30 June 2023).
Results: The prevalence of GAS in the entire population was 23.2% (n=3024). Among the groups, Group 3 had the highest ratio of GAS cases, followed by Group 1, and then Group 2 (Group 1: 18.1%, Group 2: 6.0%, Group 3: 29.6%, p < 0.001). During the period characterized by stringent measures against the COVID-19 pandemic, a significant reduction in the frequency of GAS was observed in comparison to the pre-COVID-19 era. However, with the relaxation of COVID-19-related restrictions, particularly in the last quarter of 2022 and the spring of 2023, there was a marked increase in the frequency of GAS. Conclusion: In children, the frequency of GAS significantly decreases with COVID-19 isolation measures. However, a rebound increase is observed following the relaxation of these isolation measures.

Keywords

Group A β-hemolytic streptococcus, COVID-19, strep A rapid test, tonsillopharyngitis

Ethical Statement

Çalışma Helsinki Bildirgesi'ne uygun olarak yapıldı ve Hisar Hospital Intercontinental Etik Kurulu tarafından onaylandı (Tarih: 22.09.2023, Karar No: 23-48).

Project Number

Decision No: 23-48, Date: 22.09.2023

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