DEMOGRAPHIC AND CLINICAL FEATURES OF PATIENTS WITH PRIMARY SJÖGREN’S SYNDROME IN ANTALYA

Year 2019, Volume: 2 Issue: 2, 1 - 7, 31.12.2019

Mesut Göçer

Abstract

Abstract

Background: Sjögren’s syndrome (SS) is an autoimmune disease with
a broad range of systemic manifestations.
This study was conducted to determine demographic and clinical features of primary SS patients.

 

Methods: In this study were included the patients with primary
SS (pSS) diagnosed between 2004-2014 years at the Akdeniz University Hospital,
Antalya, Turkey. The
clinical and laboratory features were retrospectively obtained from medical
charts.

 

Results: We had 718 patients with suspected pSS at
10 years. 372 patients were classified as pSS according
to 2012 American Collage of Rheumatology Classification Criteria for Sjögren’s
Syndrome. pSS was more frequent among women and ratio women/men
was 11/1. The mean age at the time of
pSS diagnosis was 50.3±11.81 years. In men, pSS was diagnosed at an older age, and lung
involvement was common than women. Joint involvement is the
most common extraglandular involvement. Anemia is present in 21.1 % of the
patients. Malignancy was diagnosed in 14 patients (3.8%) and 18 patients died (4.8%) during follow-up. Hydroxychloroquine
is the most preferred drug as a therapeutic agent

 

Conclusions: Features of primary SS obtained in this study are
similar to those found in some national and international studies, but we
observed lung involvement higher male than female.

Keywords

Sjögren Syndrome, Demographic, Clinical Features, Retrospective

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