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The correlations between serum thyroid hormone levels, crime, impulsivity and aggression in high-security forensic psychiatry service patients

Year 2022, Volume: 5 Issue: 3, 174 - 181, 30.12.2022
https://doi.org/10.56150/tjhsl.1200321

Abstract

Objective: High security forensic psychiatry services (HSFP) are increasingly popular institutions in Turkey, since they play a key role in the follow-up and treatment of patients. Thyroid hormone is known to be associated with certain psychiatric diseases. We investigated the correlations between serum thyroid hormone levels, criminality, impulsivity and aggression in criminal patients who received treatment in HSFP.
Material and method: The study was conducted with 115 patients who presented in HSFP and met the study criteria and 115 healthy controls. Sociodemographic and Clinical Data Forms, Barratt Impulsivity Scale Short Form (BrIS-SF-11), Buss-Perry Aggression Scale (BPAS) were applied to all participants. Furthermore, serum TSH, serum free T3 and T4 levels were determined in the patient and control groups.
Results: The sT3 and sT4 levels were significantly higher in the patient group when compared to the control group (p<0.001). A negative significant correlation was determined between TSH and sT4 in the patient group (r=-.197, p= .035). There was no significant difference between the criminality based on the serum TSH levels (p>0.001). There was no significant difference between the TSH levels in the two groups (p>0.001). Furthermore, it was determined that BrIS-SF-11 sub-dimension scores and the total score, BPRS sub-dimension scores and the total score were significantly higher in the patient group when compared to the healthy controls (p<0.001).
Conclusion: It was observed that the impulsivity and aggression levels of the criminal patients who were followed up and treated in HSFP were higher. The present study demonstrated that serum thyroid hormone levels of individuals who committed criminal offenses could be associated with impulsivity and aggression; however, further studies are required for clarification.

References

  • Anderson CA, Bushman BJ. Human aggression. Annu Rev Psychol. 2002; 53:27- 51.
  • Karababa A. Kahramanmaraş’ın Suç Profili ve Çözüm Önerileri. Kahramanmaraş Sütçü İmam Üniversitesi SBE, İktisat ABD, Yayınlanmamış Yüksek Lisans Projesi, 2007.
  • Van de Weijer SGA, Leukfeldt ER. Big five personality traits of cybercrime victims. Cyberpsychol Behav Soc Netw. 2017; 20(7):407- 12.
  • Boillat C, Deuring G, pflueger MO, Graf M, Rosburg T. Neuroticism in child sex offenders and its association with sexual dysfunctions, cognitive distortions, and psychological complaints. Int J Law psychiatry, 2017;54:83-9.
  • Whiting D, Lichtenstein P, Fazel S. Violence and mental disorders: a structured review of associations by individual diagnoses, risk factors, and risk assessment. Lancet Psychiatry, 2021;8(2):150-61.
  • Emir BS, Kazğan A, Kurt O, Yıldız S. Sociodemographic Characteristics of Persons Treated in the High Security Forensic Psychiatry Service: A Retrospective Study. Medical Records, 2022; 4(1): 73-80.
  • Balcıoğlu YH. Koruyucu ve Toplum Temelli Psikiyatri Perspektifinden Adli Psikiyatri: Suçun ve Şiddet Davranışının Önlenmesi.
  • Yazıcı K, Yazıcı AE. Dürtüselliğin nöroanatomik ve nörokimyasal temelleri. Psikiyatride Güncel Yaklaşımlar, 2010; 22:54-280.
  • Bozkurt M. Alkol Ve Eroin Bağımlılığı Olan İki Ayrı Grupta Dürtüsellik Ve Agresyonun Kişilik Özellikleri İle İlişkisi. Bakırköy Prof. Dr. Mazhar Osman Ruh Sağlığı Ve Sinir Hastalıkları Eğitim Ve Araştırma Hastanesi, Tıpta Uzmanlık Tezi, İstanbul, 2002.
  • Hoptman MJ, Ardekani BA, Butler PD, Nierenberg J, Javitt DC, Lim KO. DTI and impulsivity in schizophrenia: a first voxelwise correlational analysis. Neuroreport, 2004;15:2467-2470.
  • Demir NÖ, Tuğlu C. Bipolar bozukluk hastalarında metabolik sendrom ve dürtüsellik ilişkisi. Anadolu Psikiyatri Dergisi, 2020;21(3): 277-284.
  • Kazğan A, Yıldız S, Kurt O, Korkmaz S. Sınırda kişilik bozukluğunda serum ürik asit seviyeleri ve dürtüsellikle ilişkisi. Cukurova Medical Journal, 2021;46(4): 1624-1631.
  • Özdemir PG, Selvi Y, Aydın A. Dürtüsellik ve tedavisi. Psikiyatride Güncel Yaklaşımlar, 2012; 4(3): 293-314.
  • Nehir S, Irmak H, Demet MM, Toksöz K. Bipolar bozuklukta çocukluk çağı travmaları ve agresyon ilişkisi. Anadolu Psikiyatri Dergisi, 2018; 19(2): 163-168.
  • Böke Ö, Sarısoy G, Çelik C, Aker S, Bahçe Z, Rıfat Şahin A. Yatarak Tedavi Gören Şizofreni Hastalarında Fiziksel Saldırganlık ve Nörolojik Silik İşaretler. Klinik Psikofarmakoloji Bulteni, 2008; 18(1):22-30.
  • Gürkan Ş, Yaylacı ET, Özdemir Ç, Çatlı B, Şahiner ŞY, Gürkan D, Göka E. Suç işlemiş ve işlememiş şizofreni hastalarının sosyodemografik verileri, psikopati ve saldırganlık düzeylerinin karşılaştırılması. Anadolu Psikiyatri Dergisi,2019; 20(3):261-268.
  • Bevilacqua L, Doly S, Kaprio J, Yuan Q, Tikkanen R, Paunio T, Zhou Z, Wedenoja J, Maroteaux L, Diaz S, Belmer A, Hodgkinson CA, Dell'Osso L, Suvisaari J, Coccaro E, Rose RJ, Palotie L, Virkkunen M, Goldman D. A population-specific HTR2B stop codon predisposes to severe impulsivity. Nature, 2010;468:1061–1066.
  • Terracciano A, Esko T, Sutin AR, De Moor MHM, Meirelles O, Zhu G, … Uda M. Meta-analysis of genome-wide association studies identifies common variants in CTNNA2 associated with excitement-seeking. Transl Psychiatry, 2011;1(10):e49.
  • Harrison Endokrinoloji. J Larry Jameson, Çeviri Editörü Abdullah Bereket, Nobel Tıp Kitabevi, 2009, Ankara.
  • Evrensel A, Ünsalver BÖ, Özsahin A. Antisosyal Kisilik Bozuklugu Tanili Bireylerde Saldirganlik Ile Serum Tiroid Hormon Düzeyleri Arasindaki Iliski/The Relationship between Aggression and Serum Thyroid Hormone Level in Individuals Diagnosed with Antisocial Personality Disorder. Noro-Psikyatri Arsivi, 2016; 53(2): 120.
  • Stalenheim EG. Long-term validity of biological markers of psychopathy and criminal recidivism: follow-up 6-8 years after forensic psychiatric investigation. Psychiatry Research, 2004; 121: 281-291
  • Daly RC, Su PT, Schmidt PJ, Pagliaro M, Pickar D, Rubinow DR. Neuroendocrine and behavioral effects of high-dose anabolic steroid administration in male normal volunteers. Psychoneuroendocrinology, 2003;28:317-331.
  • Patton JH, Stanford MS, Barratt ES. Factor structure of the Barratt impulsiveness scale. J Clin Psychol. 1995;51: 768-774.
  • Güleç H, Tamam L, Güleç MY, Turhan M, Karakuş G, Zengin M, Stanford MS. Barratt dürtüsellik ölçeği-11 (BIS-11)’nin Türkçe uyarlamasının psikometrik özellikleri. Klinik Psikofarmakoloji Bülteni, 2008;18: 251-258.
  • Can S. Türk Popülasyonunda Saldırganlık Ölçeğinin Türkçe Uyarlamasının Geçerlik ve Güvenirlik Çalışması, Ruh Sağlığı ve Hastalıkları AD. Tıpta Uzmanlık Tezi, İstanbul: GATA; 2002.
  • Buss AH, Perry M. The aggression questionnaire. J Pers Soc Psychol. 1992;63:452–459.
  • Ceylan ME, Maner F. Impulse control disorder can be an early predictor of thyroid dysfunction. Anatolian Journal of Psychiatry, 2011;12(3): 241-242.
  • Villanger GD, Ystrom E, Engel SM, Longnecker MP, Pettersen R, Rowe AD, Reichborn‐Kjennerud T, Aase H. Neonatal thyroid-stimulating hormone and association with attention-deficit/hyperactivity disorder Paediatr. Perinat. Epidemiol. 2020;34 (5): pp. 590-596
  • Modesto T, Tiemeier H, Peeters RP, Jaddoe VWV, Hofman A, Verhulst FC, Ghassabian A. Maternal mild thyroid hormone insufficiency in early pregnancy and attention-deficit/hyperactivity disorder symptoms in children JAMA Pediatrics, 2015;169 (9): p. 838-845
  • Stalenheim EG, von Knorring L, Wide L. Serum levels of thyroid hormones as biological markers in a Swedish forensic psychiatric population. Biological Psychiatry, 1998;43: 755–761
  • Sinai C, Hirvikoski T, Vansvik ED, Nordström AL, Linder J, Nordström P, Jokinen J. Thyroid hormones and personality traits in attempted suicide. Psychoneuroendocrinology, 2009; 34(10): 1526-1532.
  • Alm PO, Klinteberg B, Humble K, Leppert J, Sorensen S, Tegelman R, Thorell LH, Lidberg L. Criminality and psychopathy as related to thyroid activity in former juvenile delinquents. Acta Psychiatrica Scandinavica 1996; 94:112-117.
  • Öncü B, Şenol S. Dikkat hiperaktivite bozukluğunun etiyolojisi: Bütüncül karantina. Klin Psikiyatr Derg. 2002; 5: 111–9.
  • Acar H, Ulgen A. Relationship between thyroid hormone levels and crime type: a controlled study in prisoners. Int J Endocrinol. 2020; 2020: 9172134. doi: 10.1155/2020/9172134.
  • Dodman NH, Aronson L, Cottam N, Dodds JW. The effect of thyroid replacement in dogs with suboptimal thyroid function on owner-directed aggression: A randomized, double-blind, placebo-controlled clinical trial. Journal of Veterinary Behavior, 2013; 8(4): 225-230.
  • Ozsoy S, Esel E, Izgi HB, Sofuoglu S. Thyroid function in early and late alcohol withdrawal: relationship with aggression, family history, and onset age of alcoholism. Alcohol and alcoholism, 2006; 41(5): 515-521.
  • Yağcı I, Avcı S, Taşdelen Y, Kıvrak Y. İntihar girişiminde bulunanlarda D tipi kişilik, çocukluk çağı travmaları, depresyon, anksiyete, dürtüsellik. Anadolu Psikiyatri Dergisi, 2018;19(6): 551-558.
  • Kazǧan A, Yıldız S, Korkmaz S, Atmaca M. Auto-vampirism in borderline personality disorder: A case report Borderline kişilik bozukluǧunda oto-vampirizm: Olgu sunumu. Klinik Psikiyatri Dergisi, 2021;24:265-269.
  • Kertzman S, Kagan A, Vainder M, Lapidus R, Weizman A. Interactions between risky decisions, impulsiveness and smoking in young tattooed women. BMC psychiatry, 2013;13(1): 1-8.
  • Köksal B, Karaca S, Çıtak S. Madde bağımlılığında dürtüsellik ve saldırganlığın incelenmesi. Klinik Psikiyatri Dergisi, 2020; 23(1): 23-33.
Year 2022, Volume: 5 Issue: 3, 174 - 181, 30.12.2022
https://doi.org/10.56150/tjhsl.1200321

Abstract

References

  • Anderson CA, Bushman BJ. Human aggression. Annu Rev Psychol. 2002; 53:27- 51.
  • Karababa A. Kahramanmaraş’ın Suç Profili ve Çözüm Önerileri. Kahramanmaraş Sütçü İmam Üniversitesi SBE, İktisat ABD, Yayınlanmamış Yüksek Lisans Projesi, 2007.
  • Van de Weijer SGA, Leukfeldt ER. Big five personality traits of cybercrime victims. Cyberpsychol Behav Soc Netw. 2017; 20(7):407- 12.
  • Boillat C, Deuring G, pflueger MO, Graf M, Rosburg T. Neuroticism in child sex offenders and its association with sexual dysfunctions, cognitive distortions, and psychological complaints. Int J Law psychiatry, 2017;54:83-9.
  • Whiting D, Lichtenstein P, Fazel S. Violence and mental disorders: a structured review of associations by individual diagnoses, risk factors, and risk assessment. Lancet Psychiatry, 2021;8(2):150-61.
  • Emir BS, Kazğan A, Kurt O, Yıldız S. Sociodemographic Characteristics of Persons Treated in the High Security Forensic Psychiatry Service: A Retrospective Study. Medical Records, 2022; 4(1): 73-80.
  • Balcıoğlu YH. Koruyucu ve Toplum Temelli Psikiyatri Perspektifinden Adli Psikiyatri: Suçun ve Şiddet Davranışının Önlenmesi.
  • Yazıcı K, Yazıcı AE. Dürtüselliğin nöroanatomik ve nörokimyasal temelleri. Psikiyatride Güncel Yaklaşımlar, 2010; 22:54-280.
  • Bozkurt M. Alkol Ve Eroin Bağımlılığı Olan İki Ayrı Grupta Dürtüsellik Ve Agresyonun Kişilik Özellikleri İle İlişkisi. Bakırköy Prof. Dr. Mazhar Osman Ruh Sağlığı Ve Sinir Hastalıkları Eğitim Ve Araştırma Hastanesi, Tıpta Uzmanlık Tezi, İstanbul, 2002.
  • Hoptman MJ, Ardekani BA, Butler PD, Nierenberg J, Javitt DC, Lim KO. DTI and impulsivity in schizophrenia: a first voxelwise correlational analysis. Neuroreport, 2004;15:2467-2470.
  • Demir NÖ, Tuğlu C. Bipolar bozukluk hastalarında metabolik sendrom ve dürtüsellik ilişkisi. Anadolu Psikiyatri Dergisi, 2020;21(3): 277-284.
  • Kazğan A, Yıldız S, Kurt O, Korkmaz S. Sınırda kişilik bozukluğunda serum ürik asit seviyeleri ve dürtüsellikle ilişkisi. Cukurova Medical Journal, 2021;46(4): 1624-1631.
  • Özdemir PG, Selvi Y, Aydın A. Dürtüsellik ve tedavisi. Psikiyatride Güncel Yaklaşımlar, 2012; 4(3): 293-314.
  • Nehir S, Irmak H, Demet MM, Toksöz K. Bipolar bozuklukta çocukluk çağı travmaları ve agresyon ilişkisi. Anadolu Psikiyatri Dergisi, 2018; 19(2): 163-168.
  • Böke Ö, Sarısoy G, Çelik C, Aker S, Bahçe Z, Rıfat Şahin A. Yatarak Tedavi Gören Şizofreni Hastalarında Fiziksel Saldırganlık ve Nörolojik Silik İşaretler. Klinik Psikofarmakoloji Bulteni, 2008; 18(1):22-30.
  • Gürkan Ş, Yaylacı ET, Özdemir Ç, Çatlı B, Şahiner ŞY, Gürkan D, Göka E. Suç işlemiş ve işlememiş şizofreni hastalarının sosyodemografik verileri, psikopati ve saldırganlık düzeylerinin karşılaştırılması. Anadolu Psikiyatri Dergisi,2019; 20(3):261-268.
  • Bevilacqua L, Doly S, Kaprio J, Yuan Q, Tikkanen R, Paunio T, Zhou Z, Wedenoja J, Maroteaux L, Diaz S, Belmer A, Hodgkinson CA, Dell'Osso L, Suvisaari J, Coccaro E, Rose RJ, Palotie L, Virkkunen M, Goldman D. A population-specific HTR2B stop codon predisposes to severe impulsivity. Nature, 2010;468:1061–1066.
  • Terracciano A, Esko T, Sutin AR, De Moor MHM, Meirelles O, Zhu G, … Uda M. Meta-analysis of genome-wide association studies identifies common variants in CTNNA2 associated with excitement-seeking. Transl Psychiatry, 2011;1(10):e49.
  • Harrison Endokrinoloji. J Larry Jameson, Çeviri Editörü Abdullah Bereket, Nobel Tıp Kitabevi, 2009, Ankara.
  • Evrensel A, Ünsalver BÖ, Özsahin A. Antisosyal Kisilik Bozuklugu Tanili Bireylerde Saldirganlik Ile Serum Tiroid Hormon Düzeyleri Arasindaki Iliski/The Relationship between Aggression and Serum Thyroid Hormone Level in Individuals Diagnosed with Antisocial Personality Disorder. Noro-Psikyatri Arsivi, 2016; 53(2): 120.
  • Stalenheim EG. Long-term validity of biological markers of psychopathy and criminal recidivism: follow-up 6-8 years after forensic psychiatric investigation. Psychiatry Research, 2004; 121: 281-291
  • Daly RC, Su PT, Schmidt PJ, Pagliaro M, Pickar D, Rubinow DR. Neuroendocrine and behavioral effects of high-dose anabolic steroid administration in male normal volunteers. Psychoneuroendocrinology, 2003;28:317-331.
  • Patton JH, Stanford MS, Barratt ES. Factor structure of the Barratt impulsiveness scale. J Clin Psychol. 1995;51: 768-774.
  • Güleç H, Tamam L, Güleç MY, Turhan M, Karakuş G, Zengin M, Stanford MS. Barratt dürtüsellik ölçeği-11 (BIS-11)’nin Türkçe uyarlamasının psikometrik özellikleri. Klinik Psikofarmakoloji Bülteni, 2008;18: 251-258.
  • Can S. Türk Popülasyonunda Saldırganlık Ölçeğinin Türkçe Uyarlamasının Geçerlik ve Güvenirlik Çalışması, Ruh Sağlığı ve Hastalıkları AD. Tıpta Uzmanlık Tezi, İstanbul: GATA; 2002.
  • Buss AH, Perry M. The aggression questionnaire. J Pers Soc Psychol. 1992;63:452–459.
  • Ceylan ME, Maner F. Impulse control disorder can be an early predictor of thyroid dysfunction. Anatolian Journal of Psychiatry, 2011;12(3): 241-242.
  • Villanger GD, Ystrom E, Engel SM, Longnecker MP, Pettersen R, Rowe AD, Reichborn‐Kjennerud T, Aase H. Neonatal thyroid-stimulating hormone and association with attention-deficit/hyperactivity disorder Paediatr. Perinat. Epidemiol. 2020;34 (5): pp. 590-596
  • Modesto T, Tiemeier H, Peeters RP, Jaddoe VWV, Hofman A, Verhulst FC, Ghassabian A. Maternal mild thyroid hormone insufficiency in early pregnancy and attention-deficit/hyperactivity disorder symptoms in children JAMA Pediatrics, 2015;169 (9): p. 838-845
  • Stalenheim EG, von Knorring L, Wide L. Serum levels of thyroid hormones as biological markers in a Swedish forensic psychiatric population. Biological Psychiatry, 1998;43: 755–761
  • Sinai C, Hirvikoski T, Vansvik ED, Nordström AL, Linder J, Nordström P, Jokinen J. Thyroid hormones and personality traits in attempted suicide. Psychoneuroendocrinology, 2009; 34(10): 1526-1532.
  • Alm PO, Klinteberg B, Humble K, Leppert J, Sorensen S, Tegelman R, Thorell LH, Lidberg L. Criminality and psychopathy as related to thyroid activity in former juvenile delinquents. Acta Psychiatrica Scandinavica 1996; 94:112-117.
  • Öncü B, Şenol S. Dikkat hiperaktivite bozukluğunun etiyolojisi: Bütüncül karantina. Klin Psikiyatr Derg. 2002; 5: 111–9.
  • Acar H, Ulgen A. Relationship between thyroid hormone levels and crime type: a controlled study in prisoners. Int J Endocrinol. 2020; 2020: 9172134. doi: 10.1155/2020/9172134.
  • Dodman NH, Aronson L, Cottam N, Dodds JW. The effect of thyroid replacement in dogs with suboptimal thyroid function on owner-directed aggression: A randomized, double-blind, placebo-controlled clinical trial. Journal of Veterinary Behavior, 2013; 8(4): 225-230.
  • Ozsoy S, Esel E, Izgi HB, Sofuoglu S. Thyroid function in early and late alcohol withdrawal: relationship with aggression, family history, and onset age of alcoholism. Alcohol and alcoholism, 2006; 41(5): 515-521.
  • Yağcı I, Avcı S, Taşdelen Y, Kıvrak Y. İntihar girişiminde bulunanlarda D tipi kişilik, çocukluk çağı travmaları, depresyon, anksiyete, dürtüsellik. Anadolu Psikiyatri Dergisi, 2018;19(6): 551-558.
  • Kazǧan A, Yıldız S, Korkmaz S, Atmaca M. Auto-vampirism in borderline personality disorder: A case report Borderline kişilik bozukluǧunda oto-vampirizm: Olgu sunumu. Klinik Psikiyatri Dergisi, 2021;24:265-269.
  • Kertzman S, Kagan A, Vainder M, Lapidus R, Weizman A. Interactions between risky decisions, impulsiveness and smoking in young tattooed women. BMC psychiatry, 2013;13(1): 1-8.
  • Köksal B, Karaca S, Çıtak S. Madde bağımlılığında dürtüsellik ve saldırganlığın incelenmesi. Klinik Psikiyatri Dergisi, 2020; 23(1): 23-33.
There are 40 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Articles
Authors

Burcu Sırlıer Emir 0000-0002-3389-5790

Sevler Yıldız 0000-0002-9951-9093

Aslı Kazğan Kılıçaslan 0000-0002-0312-0476

Osman Kurt 0000-0003-4164-3611

Nevzat Gözel 0000-0001-7326-6860

Publication Date December 30, 2022
Published in Issue Year 2022 Volume: 5 Issue: 3

Cite

APA Sırlıer Emir, B., Yıldız, S., Kazğan Kılıçaslan, A., Kurt, O., et al. (2022). The correlations between serum thyroid hormone levels, crime, impulsivity and aggression in high-security forensic psychiatry service patients. Turkish Journal of Health Science and Life, 5(3), 174-181. https://doi.org/10.56150/tjhsl.1200321