Focal Segmental Glomerulosclerosis with Sjogren Syndrome: A Case Report

Year 2021, Volume: 3 Issue: Supplement 1, 107 - 109, 07.03.2021

Mehmet Sezen , Abdülmecit Yıldız , Kamil Dilek , Mustafa Güllülü , Mahmut Yavuz , Ayşegül Oruç , Mehmet Fethullah Aydın , Alparslan Ersoy

https://doi.org/10.46310/tjim.876204

Abstract

Sjogren's syndrome (SjS) is a chronic, slow-progressing, autoimmune and lymphoproliferative disease. The main symptoms of the syndrome are xerostomia and keratoconjuctivitis sicca as a result of chronic inflammatory infiltration of the salivary and lacrimal glands. Focal Segmental Glomerulosclerosis complicating primary Sjögren's syndrome is extremely rare. We report on a 39-year-old woman with 5 years history of sjogren syndrome who was found to have nephrotic syndrome. Histopathological findings in kidney biopsy compatible with focal segmental glomerulosclerosis. Steroid therapy was initiated (oral prednisolone at a dose of 15 mg/day) and Cyclosporine 2 * 100mg/d. FSGS, which is associated with sjögren's syndrome, was considered suitable for the presentation because of its rare occurrence

Keywords

sjogren syndrome, focal segmental glomerulosclerosis, nephrotic syndrome

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