Barbaloin Attenuates Oxidative Testicular Injury Induced by Ischemia Reperfusion via Antioxidant Effects

Year 2020, Volume: 5 Issue: 1, 28 - 33, 30.03.2020

Ömer Topdağı Ayhan Tanyeli , Fazile Ekinci , Ersen Eraslan Mustafa Can Güler

Abstract

The
purpose of this research is to examine the protective effects of barbaloin on
testis injury induced by ischemia reperfusion. In the experimental stage of our research,
the rats were assigned to 4 groups. Our groups are scheduled as follows; sham, ischemia
reperfusion, ischemia reperfusion + DMSO and ischemia reperfusion+barbaloin.
Some oxidant, antioxidant and inflammatory parameters were evaluated in testis tissues
obtained at the end of the experiment. In ischemia reperfusion group it was found
out that the oxidant parameters increased and antioxidant parameters decreased but
on the contrary, the antioxidant parameters increased and oxidant parameters
decreased in the treatment group. These results demonstrated that barbaloin administration
performed a protective effect against oxidative testis injury induced by ischemia
reperfusion.

Keywords

ischemia reperfusion, barbaloin, testis, oxidative stress, inflamation

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