AN EVALUATION OF QUALITY OF LIFE AND MUSCLE STRENGTH IN ADULT CANCER PATIENTS RECEIVING TREATMENT

Year 2020, Volume: 31 Issue: 3, 288 - 297, 17.12.2020

Ayşegül Atlı , Tülin Düger

https://doi.org/10.21653/tjpr.495603

Abstract

Purpose: Studies investigating muscle strength in cancer patients treating in the outpatient setting are limited. The aim of this study was to investigate the quality of life and muscle strength of adult cancer patients in the treatment stage after cancer diagnosis. Methods: A total of 54 patients (32 F, 22 M, age=49.74±12.00 years) with solid tumors, 17 (31.5%) patients receiving chemotherapy (CT Group), 20 (37.0%) treated with CT and surgery (CT+S Group), and 17 (31.5%) undergoing chemotherapy, surgery and radiotherapy (CT+S+RT) were included. Patient characteristics were recorded. Quadriceps femoris muscle strength and handgrip strength were measured. The European Cancer Research and Treatment Organization Quality of Life Questionnaire (EORTC-QLQC30- European) was used to assess quality of life. Results: According to the quality of life scores, cognitive function was affected in the CT+S+RT Group compared to CT+S Group (p<0.05). Patients receiving CT, compared to patients receiving CT+S+RT Group in terms of shortness of breath and insomnia, quality of life was negatively affected, and patients receiving CT+S+RT Group were better in terms of general well-being (p<0.05). Female patients were significantly affected in terms of physical function, role function, pain and symptoms compared to male patients (p<0.05). Handgrip strength was correlated with quality of life functional score (r=0.416, p=0.003), phsical function (r=0,232, p=0.047), and occupational function (r=0,422, p=0.011). Score, physical function, and function. There was a relationship between quadriceps femoris muscle strength and functional socre (r=0,232, p=0,047), occupational function (r=0.243, p=0.040), and cognitive function (r=0.259, p=0.030) Conclusion: Quality of life of the patients receiving cancer treatment had a negative effect and this negative effect was higher in female patients than in men. It was observed that the patients with high upper extremity muscle strength had better physical function, function and function in terms of quality of life.

Keywords

adult, cancer, cancer treatment

TEDAVİ GÖREN ERİŞKİN KANSER HASTALARINDA YAŞAM KALİTESİ VE KAS KUVVETİNİN DEĞERLENDİRİLMESİ

Abstract

Amaç: Ayaktan tedavi gören kanser hastalarında kas kuvvetini değerlendiren çalışmalar sınırlıdır. Bu çalışmanın amacı, kanser tanısı almış ve kanser tedavisi gören erişkin hastalarında kas kuvveti ile yaşam kalitesi arasındaki ilişkiyi incelemekti. Yöntem: Çalışmaya solid tümör tanısı ile ayaktan kemoterapi alan 17 (% 31,5) olgu (KT grup), kemoterapi ve cerrahi tedavi alan 20 (% 37,0) olgu (KT+C grup) ve kemoterapi, cerrahi tedavi ve radyoterapi alan 17 (% 31,5) olgu (KT+C+RT grup) olmak üzere, toplam 54 hasta (32 K, 22 E, yaş=49,74±12,00 yıl) dahil edildi. Bireylerin demografik bilgileri kaydedildi. Alt ekstremitede quadriceps femoris kas kuvveti ve üst ekstremitede el kavrama kuvveti değerlendirildi. Yaşam kalitesini değerlendirmek için Avrupa Kanser Araştırma ve Tedavi Organizasyonu Yaşam Kalitesi Anketi (EORTC-QLQ-C30-European) kullanıldı. Sonuçlar: Yaşam kalitesi skorlarına göre, KT+C+RT grubun, KT+C gruba göre kognitif fonksiyon alt boyutunun etkilendiği belirlendi (p<0,05). KT grup hastaların, KT+C+RT grup hastalara göre; nefes darlığı ve uykusuzluk alt boyutu açısından yaşam kalitesinin olumsuz yönde etkilendiği saptandı (p<0,05). KT+C+RT grup hastaların, genel iyilik hali alt boyutu açısından diğer gruplardan daha iyi oldukları bulundu (p<0,05). Kadın hastaların fiziksel fonksiyon, rol fonksiyonu, ağrı ve semptom alt boyutları bakımından erkek hastalara göre anlamlı olarak daha fazla etkilendiği saptandı (p<0,05). El kavrama kuvveti ile yaşam kalitesi fonksiyonel skor (r=0,416, p=0,003), fiziksel fonksiyon (r=0,232, p=0,047) ve rol fonksiyonu (r=0,422, p=0,011) arasında istatistiksel olarak anlamlı ilişki olduğu belirlendi. Quadriceps kas kuvveti ile fiziksel fonksiyon (r=0,232 p=0,047), rol fonksiyonu (r=0,243, p=0,040) ve kognitif fonksiyon (r=0,259 p=0,030) arasında anlamlı ilişki olduğu bulundu. Tartışma: Tedavi alan kanser hastalarında üst ve alt ekstremite kas kuvveti ile yaşam kalitesinin fiziksel, kognitif ve rol fonksiyonlarını içeren fonksiyonel skoru ile ilişkilidir. Kanser tedavisi gören tüm hastaların yaşam kalitesinin olumsuz yönde etkilenebileceği ve bu olumsuz etkilenimlerin kadın hastalarda erkeklere göre daha fazla olabileceği saptandı.

Keywords

Kanser, Tedavi, Yetişkin, Yaşam Kalitesi

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