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MANUEL LENF DRENAJI SAĞLIKLI KADINLARDA OTONOMİK FONKSİYONLARI ETKİLER Mİ?: BİR RANDOMİZE KONTROLLÜ ÇALIŞMA

Year 2024, Volume: 35 Issue: 1, 104 - 113, 20.04.2024
https://doi.org/10.21653/tjpr.1266434

Abstract

Amaç: Bu çalışma, sağlıklı kadınlarda manuel lenf drenajının (MLD) otonomik fonksiyonlar üzerindeki etkilerini incelemeyi amaçlamaktadır.
Yöntem: 40 sağlıklı kadın çalışmaya dahil edildi. Tek kör randomize kontrollü çalışmada katılımcılar MLD, sham MLD ve kontrol grubu olarak 3 gruba ayrıldı. Katılımcıların demografik bilgileri, kan basıncı ve kalp hızı değişkenliği (KHD) değerlendirildikten sonra soğuk basınç testi uygulandı. Testin hemen ardından kan basıncı ve KHD yeniden değerlendirildi. MLD grubuna MLD uygulamaları yapıldı. Sham MLD grubuna sham protokolü uygulandı. Kontrol grubundan 10 dakika sırt üstü yatmaları istendi. Uygulama sonrası katılımcılar tekrar değerlendirildi.
Sonuçlar: Sistolik kan basıncı soğuk basınç testi ile her 3 grupta da düşerken, sham MLD grubunda uygulama sonrası düşmeye devam etti (p<0,05). Soğuk basınç testi sonrası MLD, sham MLD ve kontrol gruplarında kalp atım hızında anlamlı azalma olurken, uygulama sonrası sadece MLD grubunda anlamlı düşüş devam etti (p<0,05). KHD'nin RMSSD parametresi uygulama sonrası sadece MLD grubunda anlamlı olarak arttı (p<0,05). RR aralığı değeri hem soğuk basınç testi hem de uygulama sonrası MLD ve kontrol gruplarında arttı (p<0,05).
Tartışma: MLD, KHD parametrelerindeki değişiklik nedeniyle parasempatik sinir sisteminin aktivasyonunda kullanılabilir. Parasempatik sinir sistemi aktivasyonu özellikle otonomik etkilenim olan bazı hastalıkların tedavisinde önemli bir tedavi yaklaşımı olabilir.

References

  • Gibbons CH. Basics of autonomic nervous system function. Handb. Clin. Neurol. 2019;160: 407-418.
  • Hall JE, Hall ME. Guyton and Hall Textbook of Medical Physiology E-Book. Elsevier Health Sciences; 2020. 1156 s.
  • Low PA, Tomalia VA, Park KJ. Autonomic Function Tests: Some Clinical Applications. J Clin Neurol Seoul Korea. Ocak 2013;9(1):1- 8.
  • Baek HJ, Cho CH, Cho J, Woo JM. Reliability of ultra-short-term analysis as a surrogate of standard 5-min analysis of heart rate variability. Telemed E-Health. 2015;21(5):404-14.
  • Pham T, Lau ZJ, Chen SA, Makowski D. Heart rate variability in psychology: a review of HRV indices and an analysis tutorial. Sensors. 2021; 21(12), 3998.
  • Shaffer F, Ginsberg JP. An Overview of Heart Rate Variability Metrics and Norms. Front Public Healt. 2017;258.
  • Wittlinger G, Wittlinger H. Textbook of Dr. Vodder’s manual lymph drainage. Thieme; 2004.
  • Williams A. Manual lymphatic drainage: exploring the history and evidence base. Br J Community Nurs. 2010;15(Sup3):S18-24.
  • Schingale FJ, Esmer M, Küpeli B, Ünal D. Investigation of the Less Known Effects of Manual Lymphatic Drainage: A Narrative Review. Lymphat Res Biol. 2022;20(1):7-10.
  • Obrist PA. Cardiovascular Psychophysiology: A Perspective. Springer Science & Business Media; 2012. 241 s.
  • La Cesa S, Tinelli E, Toschi N, Di Stefano G, Collorone S, Aceti A, et al. fMRI pain activation in the periaqueductal gray in healthy volunteers during the cold pressor test. Magn Reson Imaging. 2014;32(3):236-40.
  • Kim SJ, Kwon OY, Yi CH. Effects of manual lymph drainage on cardiac autonomic tone in healthy subjects. Int J Neurosci. 2009;119(8):1105-17.
  • Honguten A, Mekhora K, Pichaiyongwongdee S, Somprasong S. Effects of lymphatic drainage therapy on autonomic nervous system responses in healthy subjects: A single blind randomized controlled trial. J Bodyw Mov Ther. 2021;27:169-75.
  • Kim SJ. Effects of manual lymph drainage on the activity of sympathetic nervous system, anxiety, pain, and pressure pain threshold in subjects with psychological stress. J Korean Phys Ther. 2014;26(6):391-7.
  • Esmer M, Keser I, Erer D, Kupeli B. Acute cardiovascular responses to the application of manual lymphatic drainage in different body regions. Lymphat Res Biol. 2019;17(3):362-7.
  • Özder F, Büyükyılmaz F. Otomatik ve Manuel Kan Basıncı Ölçümü Araçlarının Güvenirliğinin İncelenmesi. Kardiyovasküler Hemşirelik Dergisi. 2022; 13(30), 14-21.
  • Gilgen-Ammann R, Schweizer T, Wyss T. RR interval signal quality of a heart rate monitor and an ECG Holter at rest and during exercise. Eur J Appl Physiol. 2019;119(7):1525-32.
  • Moya-Ramon M, Mateo-March M, Peña-González I, Zabala M, Javaloyes A. Validity and reliability of different smartphones applications to measure HRV during short and ultra-short measurements in elite athletes. Comput Methods Programs Biomed. 01 Nisan 2022;217:106696.
  • McIntyre MH, Team 23andMe Research, Kless A, Hein P, Field M, Tung JY. Validity of the cold pressor test and pain sensitivity questionnaire via online self-administration. PLoS One. 2020;15(4):e0231697.
  • Pouwels S, Van Genderen ME, Kreeftenberg HG, Ribeiro R, Parmar C, Topal B, et al. Utility of the cold pressor test to predict future cardiovascular events. Expert Rev Cardiovasc Ther. 2019;17(4):305-18.
  • Lamotte G, Boes CJ, Low PA, Coon EA. The expanding role of the cold pressor test: a brief history. Clin Auton Res. 2021; 31, 153- 155.
  • Huang M, Yoo JK, Stickford AS, Moore JP, Hendrix JM, Crandall CG, et al. Early sympathetic neural responses during a cold pressor test linked to pain perception. Clin Auton Res. 2021;31(2):215- 24.
  • Yoo JK, Badrov MB, Huang M, Bain RA, Dorn RP, Anderson EH, et al. Abnormal sympathetic neural recruitment patterns and hemodynamic responses to cold pressor test in women with posttraumatic stress disorder. Am J Physiol-Heart Circ Physiol. 2020;318(5):H1198-207.
  • Özvar GB, Ayvat E, Kılınç, M. Multipl Sklerozlu Bireylerde Stabilite Limitleri ve Düşme Riski Arasındaki İlişkinin İncelenmesi. Turk J Physiother Rehabil. 2022; 33(3), 165-171.
  • Paravati S, Warrington SJ. Physiology, Catecholamines. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing. 2018.
  • Dodo N, Hashimoto R. The effect of anxiety sensitivity on the autonomic nervous reaction during the cold pressor test: a pilot study. Int J Psychol Behav Sci. 2015;5:179-83.
  • Ziemssen T, Siepmann T. The investigation of the cardiovascular and sudomotor autonomic nervous syste —a review. Front Neurol. 2019;10:53.
  • Becker RC. Autonomic dysfunction in SARS-COV-2 infection acute and long-term implications COVID-19 editor’s page series. J Thromb Thrombolysis. 2021;52(3):692-707.
  • Armijo-Olivo S, Dennett L, Arienti C, Dahchi M, Arokoski J, Heinemann AW, Malmivaara A. Blinding in rehabilitation research: empirical evidence on the association between blinding and treatment effect estimates. Am J Phys Med Rehabil. 2020; 99(3), 198-209.
  • So PS, Jiang JY, Qin Y. Touch therapies for pain relief in adults. Cochrane Database Syst Rev. 2008;(4). CD006535.

DOES MANUAL LYMPH DRAINAGE AFFECT AUTONOMIC FUNCTIONS IN HEALTHY WOMEN?: A RANDOMIZED CONTROLLED STUDY

Year 2024, Volume: 35 Issue: 1, 104 - 113, 20.04.2024
https://doi.org/10.21653/tjpr.1266434

Abstract

Purpose: This study aimed to examine the effects of manual lymph drainage (MLD) on autonomic functions in healthy women.
Methods: 40 women were included in the study. In the single-blind randomized controlled study, the participants were divided into 3 groups MLD, sham MLD, and control group. After evaluating the demographic information, blood pressure (BP), and heart rate variability (HRV) of the participants, the cold pressure test was applied. Immediately after the test, BP and HRV were re-evaluated. The MLD group received MLD applications. A sham protocol was applied to the sham MLD group. The control group was asked to lie on their back for 10 minutes. After the application, participants were re-evaluated.
Results: While systolic BP decreased in all 3 groups with the cold pressure test, it continued to decrease after the application in the sham MLD group (p<0.05). While there was a significant decrease in heart rate in the MLD, sham MLD, and control groups after the cold pressure test, a significant decrease continued only in the MLD group after the application (p<0.05). The RMSSD parameter of HRV increased significantly only in the MLD group after the application (p<0.05). The RR interval value increased both after the cold pressure test and after the application in MLD and control groups (p<0.05).
Conclusion: MLD can be used in the activation of parasympathetic nervous system (PNS) due to the change in HRV parameters. PNS activation can be an important therapeutic approach in the treatment of some diseases, especially those with autonomic involvement.

References

  • Gibbons CH. Basics of autonomic nervous system function. Handb. Clin. Neurol. 2019;160: 407-418.
  • Hall JE, Hall ME. Guyton and Hall Textbook of Medical Physiology E-Book. Elsevier Health Sciences; 2020. 1156 s.
  • Low PA, Tomalia VA, Park KJ. Autonomic Function Tests: Some Clinical Applications. J Clin Neurol Seoul Korea. Ocak 2013;9(1):1- 8.
  • Baek HJ, Cho CH, Cho J, Woo JM. Reliability of ultra-short-term analysis as a surrogate of standard 5-min analysis of heart rate variability. Telemed E-Health. 2015;21(5):404-14.
  • Pham T, Lau ZJ, Chen SA, Makowski D. Heart rate variability in psychology: a review of HRV indices and an analysis tutorial. Sensors. 2021; 21(12), 3998.
  • Shaffer F, Ginsberg JP. An Overview of Heart Rate Variability Metrics and Norms. Front Public Healt. 2017;258.
  • Wittlinger G, Wittlinger H. Textbook of Dr. Vodder’s manual lymph drainage. Thieme; 2004.
  • Williams A. Manual lymphatic drainage: exploring the history and evidence base. Br J Community Nurs. 2010;15(Sup3):S18-24.
  • Schingale FJ, Esmer M, Küpeli B, Ünal D. Investigation of the Less Known Effects of Manual Lymphatic Drainage: A Narrative Review. Lymphat Res Biol. 2022;20(1):7-10.
  • Obrist PA. Cardiovascular Psychophysiology: A Perspective. Springer Science & Business Media; 2012. 241 s.
  • La Cesa S, Tinelli E, Toschi N, Di Stefano G, Collorone S, Aceti A, et al. fMRI pain activation in the periaqueductal gray in healthy volunteers during the cold pressor test. Magn Reson Imaging. 2014;32(3):236-40.
  • Kim SJ, Kwon OY, Yi CH. Effects of manual lymph drainage on cardiac autonomic tone in healthy subjects. Int J Neurosci. 2009;119(8):1105-17.
  • Honguten A, Mekhora K, Pichaiyongwongdee S, Somprasong S. Effects of lymphatic drainage therapy on autonomic nervous system responses in healthy subjects: A single blind randomized controlled trial. J Bodyw Mov Ther. 2021;27:169-75.
  • Kim SJ. Effects of manual lymph drainage on the activity of sympathetic nervous system, anxiety, pain, and pressure pain threshold in subjects with psychological stress. J Korean Phys Ther. 2014;26(6):391-7.
  • Esmer M, Keser I, Erer D, Kupeli B. Acute cardiovascular responses to the application of manual lymphatic drainage in different body regions. Lymphat Res Biol. 2019;17(3):362-7.
  • Özder F, Büyükyılmaz F. Otomatik ve Manuel Kan Basıncı Ölçümü Araçlarının Güvenirliğinin İncelenmesi. Kardiyovasküler Hemşirelik Dergisi. 2022; 13(30), 14-21.
  • Gilgen-Ammann R, Schweizer T, Wyss T. RR interval signal quality of a heart rate monitor and an ECG Holter at rest and during exercise. Eur J Appl Physiol. 2019;119(7):1525-32.
  • Moya-Ramon M, Mateo-March M, Peña-González I, Zabala M, Javaloyes A. Validity and reliability of different smartphones applications to measure HRV during short and ultra-short measurements in elite athletes. Comput Methods Programs Biomed. 01 Nisan 2022;217:106696.
  • McIntyre MH, Team 23andMe Research, Kless A, Hein P, Field M, Tung JY. Validity of the cold pressor test and pain sensitivity questionnaire via online self-administration. PLoS One. 2020;15(4):e0231697.
  • Pouwels S, Van Genderen ME, Kreeftenberg HG, Ribeiro R, Parmar C, Topal B, et al. Utility of the cold pressor test to predict future cardiovascular events. Expert Rev Cardiovasc Ther. 2019;17(4):305-18.
  • Lamotte G, Boes CJ, Low PA, Coon EA. The expanding role of the cold pressor test: a brief history. Clin Auton Res. 2021; 31, 153- 155.
  • Huang M, Yoo JK, Stickford AS, Moore JP, Hendrix JM, Crandall CG, et al. Early sympathetic neural responses during a cold pressor test linked to pain perception. Clin Auton Res. 2021;31(2):215- 24.
  • Yoo JK, Badrov MB, Huang M, Bain RA, Dorn RP, Anderson EH, et al. Abnormal sympathetic neural recruitment patterns and hemodynamic responses to cold pressor test in women with posttraumatic stress disorder. Am J Physiol-Heart Circ Physiol. 2020;318(5):H1198-207.
  • Özvar GB, Ayvat E, Kılınç, M. Multipl Sklerozlu Bireylerde Stabilite Limitleri ve Düşme Riski Arasındaki İlişkinin İncelenmesi. Turk J Physiother Rehabil. 2022; 33(3), 165-171.
  • Paravati S, Warrington SJ. Physiology, Catecholamines. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing. 2018.
  • Dodo N, Hashimoto R. The effect of anxiety sensitivity on the autonomic nervous reaction during the cold pressor test: a pilot study. Int J Psychol Behav Sci. 2015;5:179-83.
  • Ziemssen T, Siepmann T. The investigation of the cardiovascular and sudomotor autonomic nervous syste —a review. Front Neurol. 2019;10:53.
  • Becker RC. Autonomic dysfunction in SARS-COV-2 infection acute and long-term implications COVID-19 editor’s page series. J Thromb Thrombolysis. 2021;52(3):692-707.
  • Armijo-Olivo S, Dennett L, Arienti C, Dahchi M, Arokoski J, Heinemann AW, Malmivaara A. Blinding in rehabilitation research: empirical evidence on the association between blinding and treatment effect estimates. Am J Phys Med Rehabil. 2020; 99(3), 198-209.
  • So PS, Jiang JY, Qin Y. Touch therapies for pain relief in adults. Cochrane Database Syst Rev. 2008;(4). CD006535.
There are 30 citations in total.

Details

Primary Language Turkish
Subjects Rehabilitation
Journal Section Araştırma Makaleleri
Authors

Hümeyra Kiloatar 0000-0003-4340-3443

Meltem Isıntas 0000-0001-8162-9641

Publication Date April 20, 2024
Published in Issue Year 2024 Volume: 35 Issue: 1

Cite

APA Kiloatar, H., & Isıntas, M. (2024). MANUEL LENF DRENAJI SAĞLIKLI KADINLARDA OTONOMİK FONKSİYONLARI ETKİLER Mİ?: BİR RANDOMİZE KONTROLLÜ ÇALIŞMA. Türk Fizyoterapi Ve Rehabilitasyon Dergisi, 35(1), 104-113. https://doi.org/10.21653/tjpr.1266434
AMA Kiloatar H, Isıntas M. MANUEL LENF DRENAJI SAĞLIKLI KADINLARDA OTONOMİK FONKSİYONLARI ETKİLER Mİ?: BİR RANDOMİZE KONTROLLÜ ÇALIŞMA. Turk J Physiother Rehabil. April 2024;35(1):104-113. doi:10.21653/tjpr.1266434
Chicago Kiloatar, Hümeyra, and Meltem Isıntas. “MANUEL LENF DRENAJI SAĞLIKLI KADINLARDA OTONOMİK FONKSİYONLARI ETKİLER Mİ?: BİR RANDOMİZE KONTROLLÜ ÇALIŞMA”. Türk Fizyoterapi Ve Rehabilitasyon Dergisi 35, no. 1 (April 2024): 104-13. https://doi.org/10.21653/tjpr.1266434.
EndNote Kiloatar H, Isıntas M (April 1, 2024) MANUEL LENF DRENAJI SAĞLIKLI KADINLARDA OTONOMİK FONKSİYONLARI ETKİLER Mİ?: BİR RANDOMİZE KONTROLLÜ ÇALIŞMA. Türk Fizyoterapi ve Rehabilitasyon Dergisi 35 1 104–113.
IEEE H. Kiloatar and M. Isıntas, “MANUEL LENF DRENAJI SAĞLIKLI KADINLARDA OTONOMİK FONKSİYONLARI ETKİLER Mİ?: BİR RANDOMİZE KONTROLLÜ ÇALIŞMA”, Turk J Physiother Rehabil, vol. 35, no. 1, pp. 104–113, 2024, doi: 10.21653/tjpr.1266434.
ISNAD Kiloatar, Hümeyra - Isıntas, Meltem. “MANUEL LENF DRENAJI SAĞLIKLI KADINLARDA OTONOMİK FONKSİYONLARI ETKİLER Mİ?: BİR RANDOMİZE KONTROLLÜ ÇALIŞMA”. Türk Fizyoterapi ve Rehabilitasyon Dergisi 35/1 (April 2024), 104-113. https://doi.org/10.21653/tjpr.1266434.
JAMA Kiloatar H, Isıntas M. MANUEL LENF DRENAJI SAĞLIKLI KADINLARDA OTONOMİK FONKSİYONLARI ETKİLER Mİ?: BİR RANDOMİZE KONTROLLÜ ÇALIŞMA. Turk J Physiother Rehabil. 2024;35:104–113.
MLA Kiloatar, Hümeyra and Meltem Isıntas. “MANUEL LENF DRENAJI SAĞLIKLI KADINLARDA OTONOMİK FONKSİYONLARI ETKİLER Mİ?: BİR RANDOMİZE KONTROLLÜ ÇALIŞMA”. Türk Fizyoterapi Ve Rehabilitasyon Dergisi, vol. 35, no. 1, 2024, pp. 104-13, doi:10.21653/tjpr.1266434.
Vancouver Kiloatar H, Isıntas M. MANUEL LENF DRENAJI SAĞLIKLI KADINLARDA OTONOMİK FONKSİYONLARI ETKİLER Mİ?: BİR RANDOMİZE KONTROLLÜ ÇALIŞMA. Turk J Physiother Rehabil. 2024;35(1):104-13.