Alternative treatment studies for leishmaniasisis

Year 2019, Volume: 3 Issue: 1, 45 - 50, 30.04.2019

Özlem Makbule Kaya , Şerife Akküçük , Mehmet Yaman

Abstract

Leishmaniasis is a vector-borne zoonotic disease that
is common in the world. Because of the difficulties in the treatment and
control of the disease, the disease has gained popularity among researchers.
Today, however, no vaccine has been developed for human protection. Considering
the fact that the vector can survive in a wide ecosystem and the disease can be
detected in many mammals such as humans, dogs, rodents, prevention from leishmaniasis
and treatment of the disease require a combined intervention. The toxic effects
of the drugs used in the treatment of leishmaniasis, the expensive treatment
and the resistance of the parasite to the drug have led to the research of
alternative treatment methods. This review is intended to provide an overview
of leishmaniasis alternative treatment practices and to guide new
researchs.    

Keywords

Leishmania, phytotherapy, apitherapy, maggot therapy

References

• Ahmad R, Ahmad N, Naqvi AA, Shehzad A , Al-Ghamdid MS. Role of traditional Islamic and Arabic plants in cancer therapy. J Tradit Complement Med 2017; 7(2): 195-204.
• Akbari M, Oryan A , Hatam G. Application of nanotechnology in treatment of leishmaniasis: A Review. Acta Trop 2017; 172: 86-90.
• Altıntaş N. Parasitic zoonotic diseases in Turkey. Veterinaria Italiana 2008; 44(4): 633‐646.
• Andrade MA, Azevedo CD, Motta FN, et al. Essential oils: in vitro activity against Leishmania amazonensis, cytotoxicity and chemical composition. BMC Complement Altern Med 2016; 16(1): 444.
• Arrivillaga J, Rodriguez J , Oviedo M. Preliminary evaluation of maggot (Diptera: Calliphoridae) therapy as a potential treatment for leishmaniasis ulcers. Biomedica 2008; 28(2): 305-310.
• Ataş AD, Özçelik S, Sökmen A. Deri leishmanisisi etkenleri üzerine, Sivas yöresinde endemik ve endemik olmayan bitkilerin (özütlerinin) antileishmanial etkilerinin araştırlması. Turkiye Parazitol Derg 2003; 27(3):170-5.
• Atayoğlu AT, Soylu M, Silici S , İnanç N. Glycemic index values of monofloral Turkish honeys and the effect of their consumption on glucose metabolism. Turk J Med Sci 2016; 46(2): 483-488.
• Ateş F, Or E, Körpınar MA, Gönül R , Bahçeci T. Leishmaniasisin tedavisinde antimon bileşiklerinin kullanımı. YYU Veteriner Fakultesi Dergisi 2011; 22(1): 53-57.
• Aytekin S. Kutanöz layşmanyaziste tedavi yaklaşımları. Türkderm 2009; 43: 44-47.
• Balcı YI, Türk M, Özgür A, Küçüktaşçı K. Evaluation of visceral leishmaniasis diagnosis using indirect fluorescent antibody tests in 4 pediatric patients. Turkiye Parazitol Derg 2011; 35: 114-116.
• Barroso PA, Marco JD, Locatelli FM, et al. Visceral leishmaniasis caused by Leishmania infantum in Salta, Argentina: Possible reservoirs and vectors. Am J Trop Med Hyg 2015; 93(2): 334-339.
• Cam Y, Koç AN, Silici S, et al. Treatment of dermatophytosis in young cattle with propolis and Whitfield's ointment. Vet Rec 2009; 165(2): 57-58.
• Can Z, Yıldız O, Şahin H, et al. An investigation of Turkish honeys: their physico-chemical properties, antioxidant capacities and phenolic profiles. Food Chem 2015; 180: 133-141.
• Cruz-Saavedra L, Diaz-Roa A, Gaona MA, et al. The effect of Lucilia sericata and Sarconesiopsis magellanica derived larval therapy on Leishmania panamensis. Acta Trop 2016; 164: 280-289.
• Çulha G , Akçali C. Detection of cutaneous leishmaniasis cases in Hatay and surrounding areas. Turkiye Parazitol Derg 2006; 30(4): 268-271.
• Duran GG, Duran N, Çulha G, Özcan B, Öztaş H, Özer B. In vitro antileishmanial activity of Adana propolis samples on Leishmania tropica: a preliminary study. Parasitol Res 2008;102(6):1217-25.
• Durusoy Ç , Ulusal BG. Dermatolojide bitkisel tedavi-fitoterapi. Turk J Dermatol 2007;1(2):47-50.
• Eskandari EG, Doudi M , Abedi S. An in vitro study of antileishmanial effect of Portulaca oleracea extract. J Vector Borne Dis 2016; 53(4): 362-369.
• Fatima F, Khalid A, Nazar N, et al. In vitro assessment of anti - cutaneous leishmaniasis activity of some Sudanese plants. Turkiye Parazitol Derg 2005; 29(1): 3-6.
• Ferreira C, Passos CL, Soares DC, et al. Leishmanicidal activity of the alkaloid-rich fraction from Guatteria latifolia. Exp Parasitol 2017; 172: 51-60.
• Fratellone PM, Tsimis F , Fratellone G. Apitherapy Products for Medicinal Use. J Altern Complement Med 2016; 22(12): 1020-1022.
• Gönül R, Arun SS, Dodurka T, Handemir E. Bir köpekte Leishmania infantum olgusu. Turk J Vet Anim Sci 2010; 26: 689-694.
• Güneş AM, Sevinir B, Baytan B, Günay Ü, Aynacı D. Kala-azar ve lipozomal amfoterisin B ile tedavi. Çocuk Sağlığı ve Hastalıkları Dergisi 2004; 47: 103-106.
• Harman M. Kutanöz leishmaniasis. Turk J Dermatol 2015; 9: 168-176.
• İça A. Köpeklerde leishmaniosis. Erciyes Üniv Vet Fak Derg 2004; 1(2): 119-124.
• Kıvçak B, Mert T, Ertabaklar H, Balcıoğlu IC, Özensoy Töz S. In vitro activity of Arbutus unedo against Leishmania tropica promastigotes. Turkiye Parazitol Derg 2009; 33(2): 114-115.
• Kuhlencord A, Maniera T, Eibl H, Unger C. Hexadecylphosphocholine: oral treatment of visceral leishmaniasis in mice. Antimicrob Agents Chemother 1992; 36(8): 1630-1634.
• Limoncu ME, Erac B, Gurpinar T, et al. Investigation of in vitro antileishmanial activity of moxifloxacin, linezolid and caspofungin on Leishmania tropica promastigotes. Turkiye Parazitol Derg 2013; 37(1): 1-3.
• Mahmoudvand H, Saedi Dezaki E, Ezatpour B, et al. In vitro and in vivo antileishmanial activities of Pistacia vera essential oil. Planta Med 2016; 82(4): 279-284.
• Medeiros Vde F, Azevedo IM, Rego AC, et al. Antibacterial properties and healing effects of Melipona scutellaris honey in MRSA-infected wounds of rats. Acta Cir Bras 2016; 31(5): 327-332.
• Memişoğlu HR. Kutanöz leishmaniasis. Ankem Derg 1997; 11(3): 319-329.
• Mirzaei F, Bafghi AF, Mohaghegh MA, et al. In vitro anti-leishmanial activity of Satureja hortensis and Artemisia dracunculus extracts on Leishmania major promastigotes. J Parasit Dis 2016; 40(4): 1571-1574.
• Murray H, Berman J, Davies C, Saravia N. Advances in leishmaniasis. Lancet 2005; 366: 1561-1577.
• Özbilge H, Kaya EG, Albayrak S, Silici S. Anti- leishmanial activities of ethanolic extract of Kayseri propolis. African Journal of Microbiology Research 2010; 4 (7): 556-560.
• Polat E, Cakan H, Aslan M, et al. Detection of anti-leishmanial effect of the Lucilia sericata larval secretions in vitro and in vivo on Leishmania tropica: first work. Exp Parasitol 2012; 132(2): 129-134.
• Polat E, Kutlubay Z. Four cutaneous leishmaniosis case resistant to meglumine antimoniate treatment. Turkiye Parazitol Derg 2014; 38(3): 177-180.
• Reboucas-Silva J, Celes FS, Lima JB, et al. Parasite killing of Leishmania braziliensis by standardized propolis extracts. Evid Based Complement Alternat Med 2017; 1-14.
• Sanei-Dehkordi A, Khamesipour A, Akbarzadeh K, et al. Anti leishmania activity of Lucilia sericata and Calliphora vicina maggots in laboratory models. Exp Parasitol 2016; 170: 59-65.
• Saral Ö, Yıldız O, Aliyazıcıoğlu R, et al. Apitherapy products enhance the recovery of CCL4-induced hepatic damages in rats. Turk J Med Sci 2016; 46(1): 194-202.
• Sarkari B, Mohseni M, Moein MR, Shahriarirad R, Asgari Q. Effect of hydroalcoholic extract of Echinacea purpurea in combination with meglumine antimoniate on treatment of Leishmania major induced cutaneous leishmaniasis in BALB/c mice. Int J Appl Basic Med Res 2017; 7(1): 53-56.
• Veiga A, Albuquerque K, Correa ME, et al. Leishmania amazonensis and Leishmania chagasi: In vitro leishmanicide activity of Virola surinamensis (rol.) warb. Exp Parasitol 2017; 175: 68-73.
• Yaman M. Tatarcıklarla mücadele ve bu alandaki son gelişmeler. Turkiye Parazitol Derg 2008; 32(3): 280-287.
• Yazar S, Kuk S, Miman Ö, Saygı G. Saygı'nın temel tıbbi parazitoloji'si. Kayseri, Erciyes Üniversitesi Yayınları, 2016.
• Yipel FA, Acar A, Yipel M. Effect of some essential oils (Allium sativum L., Origanum majorana L.) and ozonated olive oil on the treatment of ear mites (Otodectes cynotis) in cats. Turk J Vet Anim Sci 2016; 40: 782-787.
• Yusof AM, Abd Ghafar N, Kamarudin TA, Hui CK , Yusof YA. Gelam honey potentiates ex vivo corneal keratocytes proliferation with desirable phenotype expression. BMC Complement Altern Med 2016; 16: 76.