Year 2025,
Volume: 9 Issue: 1, 13 - 17, 28.03.2025
Yasin Parlatır
,
Buğrahan Bekir Yağcı
,
Sedat Kaygusuz
,
Ferhat Arslan
,
Erdal Kara
References
- Barrs VR, Peiris M, Tam KWS, et al. SARS- CoV-2 quarantined domestic cats from COVID-19 households or close contacts, Hong Kong, China. Emerg Infect Dis. 2020; 26(12):3071-3074.
- Bennett JE, Dolin R, Blaser MJ. Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases, 9th ed. Elsevier Inc, 2019.
- Bessière P, Fusade-Boyer M, Walch M. et al. Household cases suggest that cats belonging to owners with COVID-19 have a limited role in virus transmission. Viruses. 2021; 13:673.
- Chen J, Huang C, Zhang Y, Zhang S, Jin M. Severe acute respiratory syndrome Coronavirus 2-specific antibodies in pets in Wuhan, China. J Infect. 2020; 81: 68-69.
- Deng J, Jin Y, Liu Y, et al. Serological survey of SARS-CoV-2 for experimental, domestic, companion and wild animals excludes intermediate hosts of 35 different species of animals. Trausbond Emerg Dis. 2020; 67:1745-1749.
- Fritz M, Rosolen B, Krafft E, et al. High prevalence of SARS-CoV-2 antibodies in pets from COVID-19+ households. One Health. 2021; 11:100192.
- He WP, Li BA, Zhao J, Cheng Y. Safety of convalescent sera for the treatment of viral severe acute respiratory syndrome: An experimental model in rhesus macaque. Chin Med J. 2013; 126:3790-3792.
- Hosie MJ, Epifano I, Herder V, et al. Detection of SARS-CoV-2 in respiratory samples from cats in the UK associated with human-to-cat transmission. Vet Rec. 2021; 188:247.
- Hossain MG, Javed A, Akter S, Saha S. SARS-CoV-2 host diversity: An update of natural infections and experimental evidence. J Microbiol Immunol Infect. 2021; 54:175-181.
- Kuiken T, Fouchier RA, Schutten M, et al. Newly discovered coronavirus as the primary cause of severe acute respiratory syndrome. Lancet. 2003; 362:263-270.
- Leroy EM, Ar Gouilh M, Brugère-Picoux J. The Risk of SARS-CoV-2 transmission to pets and other wild and domestic animals strongly mandates a one-health strategy to control the COVID-19 Pandemic. One Health. 2020; 10:100133.
- Martina BE, Haagmans BL, Kuiken T, et al. SARS virus infection of cats and ferrets. Nature. 2003; 425:915.
- Masters PS, Perlman S. Coronaviridae. Fields Virology, 6th ed. Lippincott: Williams and Wilkins, 2013. pp.825-858.
- Michelitsch A, Hoffmann D, Wernike K, et al. Beer M. Occurrence of antibodies against SARS-CoV-2 in the domestic cat population of Germany. Vaccines. 2020; 8:772.
- Murphy HL, Ly H. Understanding the prevalence of SARS-CoV-2 (COVID-19) exposure in companion, captive, wild, and farmed animals. Virulence. 2021; 12(1):2777-2786.
- Patterson EI, Elia G, Grassi A, et al. Evidence of exposure to SARS-CoV-2 in cats and dogs from households in Italy. Nat Commun. 2020; 11:6231.
- Rowe T, Gao G, Hogan RJ, et al. Macaque model for severe acute respiratory syndrome. Virol J. 2004; 78:11401-11404.
Schlottau K, Rissmann M, Graaf A, et al. SARS-CoV-2 in fruit bats, ferrets, pigs, and chickens: an experimental transmission study. The Lancet Microbe. 2020; 1(5):218-225.
- Schulz C, Martina B, Mirolo M, et al. SARS-CoV-2 specific antibodies in domestic cats during first COVID-19 wave, Europe. Emerg Infect Dis. 2021; 27(12):3115-3118.
- Shi J, Wen Z, Zhong G, et al. Susceptibility of ferrets, cats, dogs, and other domesticated animals to SARS-coronavirus 2. Science. 2020; 368(6494):1016-1020.
- Shi Z, Hu Z. A review of studies on animal reservoirs of the SARS coronavirus. Virus Res. 2008; 133:74-87.
- Song Z, Xu Y, Bao L, et al. From SARS to MERS, thrusting coronaviruses into the spotlight. Viruses 2019; 11(1):59.
- Stavisky J, Pinchbeck GL, German AJ, et al. Prevalence of canine enteric coronavirus in a cross-sectional survey of dogs presenting at veterinary practices, Vet Microbiol. 2010; 1(2):18–24.
- Stout AE, Andrea NM, Jaimes JA, Millet JK, Whittaker GR. Coronaviruses in cats and other companion animals: Where does SARS-CoV- 2/COVID-19 fit, Vet Microbiol. 2020; 247:108777.
- Sun Z, Thilakavathy K, Kumar SS, He G, Liu SV. Potential factors influencing repeated SARS outbreaks in China. Int J Environ Res Public Health. 2020; 17(5):1633.
- Taharaguchi S, Soma T, Hara M. Prevalence of feline coronavirus antibodies in Japanese domestic cats during the past decade. J Vet Med Sci. 2012; 74:1355-1358.
- Temmam S, Barbarino A, Maso D, et al. Absence of SARS-CoV-2 infection in cats and dogs in close contact with a cluster of COVID 19 patients in a veterinary campus. One Health. 2020; 10:100164.
- V’kovski P, Kratzel A, Steiner S, Stalder H, Thiel V. Coronavirus biology and replication: implications for SARS-CoV- 2. J Virol. 2020; 19(3):155-170.
- Wan Y, Shang J, Graham R, Baric RS, Li F. Receptor recognition by the novel Coronavirus from Wuhan: an Analysis Based on decade-long structural studies of SARS Coronavirus. J Virol. 2020; 94:1-9.
- Wang M, Yan M, Xu H, et al. SARS-CoV infection in a restaurant from palm civet. Emerg Infect Dis. 2005; 11:1860-1865.
- Wu F, Zhao S, Yu B, et al. A new coronavirus associated with human respiratory disease in China. Nature. 2020; 579(7798):265-269.
- Ye ZW, Yuan S, Yuen KS, Fung SY, Chan CP, Jin DY. Zoonotic origins of human coronaviruses. Int J Biol Sci. 2020; 16(10):1686-1697.
- Yılmaz A, Kayar A, Turan N, et al. Presence of Antibodies to SARS-CoV-2 in domestic cats in Istanbul, Turkey, before and after COVID-19 pandemic. Front Vet Sci. 2021; 8:707368.
- Zhang Q, Zhang H, Gao J, et al. A serological survey of SARS-CoV-2 in cat in Wuhan. Emerg Microbes Infect. 2020; 9:2013-2019.
- Zhao S, Schuurman N, Li W, et al. Serologic screening of severe acute respiratory syndrome coronavirus 2 infection in cats and dogs during first coronavirus disease wave, the Netherlands. Emerg Infect Dis. 2021; 1362:70.
- Zhou P, Lou YX, Wang XG, et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature, 2020; 579(7798):270-273.
Investigation of the presence of COVID-19 antibodies in house cats belonging to people with COVID-19
Year 2025,
Volume: 9 Issue: 1, 13 - 17, 28.03.2025
Yasin Parlatır
,
Buğrahan Bekir Yağcı
,
Sedat Kaygusuz
,
Ferhat Arslan
,
Erdal Kara
Abstract
Objective: Coronaviruses are viral agents with zoonotic potential that can cause disease in many animal species. Recently a novel coronavirus agent excited pandemia in humans. It was named SARS-COV-2. In addition to causing pandemia, it was reported that the agent has been detected in pets. Although it has reduced, its effectiveness since the pandemic, it continues to exist without losing its importance due to its potential. In this study, we aimed to research the presence of SARS CoV 2 Ig G specific antibodies in domestic cats whose owners were diagnosed with COVİD 19.
Materials and Methods: SARS-COV-2 specific Ig G antibodies were searched by receptor-binding domain-ELISA (RBD ELISA) method in 88 domestic cats whose owners were diagnosed at most 3 months ago and approved by The Ministry of Health of the Republic of Türkiye and have positive COVID-19 results.
Results: As a result of the study, the seroprevalence of COVİD-19 in cats was 2,27%. In the literature reviews, it was seen that there were a limited number of studies in our country.
Conclusion: This study is the first article conducted in Central Anatolia. The results show that cats can carry the potential for anthropozoonotic potential.
Ethical Statement
This study was performed according to Kırıkkale University Animal Experiments Local Ethics Committee Presidency instructions and approved by the ethics committee with decision number 2021/04-20.
Supporting Institution
The project was supported by Kırıkkale University BAP unit.
References
- Barrs VR, Peiris M, Tam KWS, et al. SARS- CoV-2 quarantined domestic cats from COVID-19 households or close contacts, Hong Kong, China. Emerg Infect Dis. 2020; 26(12):3071-3074.
- Bennett JE, Dolin R, Blaser MJ. Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases, 9th ed. Elsevier Inc, 2019.
- Bessière P, Fusade-Boyer M, Walch M. et al. Household cases suggest that cats belonging to owners with COVID-19 have a limited role in virus transmission. Viruses. 2021; 13:673.
- Chen J, Huang C, Zhang Y, Zhang S, Jin M. Severe acute respiratory syndrome Coronavirus 2-specific antibodies in pets in Wuhan, China. J Infect. 2020; 81: 68-69.
- Deng J, Jin Y, Liu Y, et al. Serological survey of SARS-CoV-2 for experimental, domestic, companion and wild animals excludes intermediate hosts of 35 different species of animals. Trausbond Emerg Dis. 2020; 67:1745-1749.
- Fritz M, Rosolen B, Krafft E, et al. High prevalence of SARS-CoV-2 antibodies in pets from COVID-19+ households. One Health. 2021; 11:100192.
- He WP, Li BA, Zhao J, Cheng Y. Safety of convalescent sera for the treatment of viral severe acute respiratory syndrome: An experimental model in rhesus macaque. Chin Med J. 2013; 126:3790-3792.
- Hosie MJ, Epifano I, Herder V, et al. Detection of SARS-CoV-2 in respiratory samples from cats in the UK associated with human-to-cat transmission. Vet Rec. 2021; 188:247.
- Hossain MG, Javed A, Akter S, Saha S. SARS-CoV-2 host diversity: An update of natural infections and experimental evidence. J Microbiol Immunol Infect. 2021; 54:175-181.
- Kuiken T, Fouchier RA, Schutten M, et al. Newly discovered coronavirus as the primary cause of severe acute respiratory syndrome. Lancet. 2003; 362:263-270.
- Leroy EM, Ar Gouilh M, Brugère-Picoux J. The Risk of SARS-CoV-2 transmission to pets and other wild and domestic animals strongly mandates a one-health strategy to control the COVID-19 Pandemic. One Health. 2020; 10:100133.
- Martina BE, Haagmans BL, Kuiken T, et al. SARS virus infection of cats and ferrets. Nature. 2003; 425:915.
- Masters PS, Perlman S. Coronaviridae. Fields Virology, 6th ed. Lippincott: Williams and Wilkins, 2013. pp.825-858.
- Michelitsch A, Hoffmann D, Wernike K, et al. Beer M. Occurrence of antibodies against SARS-CoV-2 in the domestic cat population of Germany. Vaccines. 2020; 8:772.
- Murphy HL, Ly H. Understanding the prevalence of SARS-CoV-2 (COVID-19) exposure in companion, captive, wild, and farmed animals. Virulence. 2021; 12(1):2777-2786.
- Patterson EI, Elia G, Grassi A, et al. Evidence of exposure to SARS-CoV-2 in cats and dogs from households in Italy. Nat Commun. 2020; 11:6231.
- Rowe T, Gao G, Hogan RJ, et al. Macaque model for severe acute respiratory syndrome. Virol J. 2004; 78:11401-11404.
Schlottau K, Rissmann M, Graaf A, et al. SARS-CoV-2 in fruit bats, ferrets, pigs, and chickens: an experimental transmission study. The Lancet Microbe. 2020; 1(5):218-225.
- Schulz C, Martina B, Mirolo M, et al. SARS-CoV-2 specific antibodies in domestic cats during first COVID-19 wave, Europe. Emerg Infect Dis. 2021; 27(12):3115-3118.
- Shi J, Wen Z, Zhong G, et al. Susceptibility of ferrets, cats, dogs, and other domesticated animals to SARS-coronavirus 2. Science. 2020; 368(6494):1016-1020.
- Shi Z, Hu Z. A review of studies on animal reservoirs of the SARS coronavirus. Virus Res. 2008; 133:74-87.
- Song Z, Xu Y, Bao L, et al. From SARS to MERS, thrusting coronaviruses into the spotlight. Viruses 2019; 11(1):59.
- Stavisky J, Pinchbeck GL, German AJ, et al. Prevalence of canine enteric coronavirus in a cross-sectional survey of dogs presenting at veterinary practices, Vet Microbiol. 2010; 1(2):18–24.
- Stout AE, Andrea NM, Jaimes JA, Millet JK, Whittaker GR. Coronaviruses in cats and other companion animals: Where does SARS-CoV- 2/COVID-19 fit, Vet Microbiol. 2020; 247:108777.
- Sun Z, Thilakavathy K, Kumar SS, He G, Liu SV. Potential factors influencing repeated SARS outbreaks in China. Int J Environ Res Public Health. 2020; 17(5):1633.
- Taharaguchi S, Soma T, Hara M. Prevalence of feline coronavirus antibodies in Japanese domestic cats during the past decade. J Vet Med Sci. 2012; 74:1355-1358.
- Temmam S, Barbarino A, Maso D, et al. Absence of SARS-CoV-2 infection in cats and dogs in close contact with a cluster of COVID 19 patients in a veterinary campus. One Health. 2020; 10:100164.
- V’kovski P, Kratzel A, Steiner S, Stalder H, Thiel V. Coronavirus biology and replication: implications for SARS-CoV- 2. J Virol. 2020; 19(3):155-170.
- Wan Y, Shang J, Graham R, Baric RS, Li F. Receptor recognition by the novel Coronavirus from Wuhan: an Analysis Based on decade-long structural studies of SARS Coronavirus. J Virol. 2020; 94:1-9.
- Wang M, Yan M, Xu H, et al. SARS-CoV infection in a restaurant from palm civet. Emerg Infect Dis. 2005; 11:1860-1865.
- Wu F, Zhao S, Yu B, et al. A new coronavirus associated with human respiratory disease in China. Nature. 2020; 579(7798):265-269.
- Ye ZW, Yuan S, Yuen KS, Fung SY, Chan CP, Jin DY. Zoonotic origins of human coronaviruses. Int J Biol Sci. 2020; 16(10):1686-1697.
- Yılmaz A, Kayar A, Turan N, et al. Presence of Antibodies to SARS-CoV-2 in domestic cats in Istanbul, Turkey, before and after COVID-19 pandemic. Front Vet Sci. 2021; 8:707368.
- Zhang Q, Zhang H, Gao J, et al. A serological survey of SARS-CoV-2 in cat in Wuhan. Emerg Microbes Infect. 2020; 9:2013-2019.
- Zhao S, Schuurman N, Li W, et al. Serologic screening of severe acute respiratory syndrome coronavirus 2 infection in cats and dogs during first coronavirus disease wave, the Netherlands. Emerg Infect Dis. 2021; 1362:70.
- Zhou P, Lou YX, Wang XG, et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature, 2020; 579(7798):270-273.