THE EFFECT OF NUTRITION ON PROTECTION AGAINST DEMENTIA: THE NEURODEGENERATIVE DELAY INTERVENTION DIET

Yıl 2022, Cilt: 2 Sayı: 3, 323 - 335, 30.09.2022

Deran Dalbudak Sansar , Aylin Seylam Küşümler

Öz

Rates of age-related diseases such as dementia are increasing every year. Preservation of membrane structure and function is important in preventing neurodegeneration and supporting optimal brain function during aging. It has been observed that the synergistic effect of different dietary micronutrient classes provides a more synergistic contribution to support membrane structure and function than exercise and stress reduction. Dietary micronutrients have been studied to maintain membrane fluidity and prevent chronic inflammation, focusing on membrane-soluble components (zeaxanthin, lutein, vitamin E, and omega-3 polyunsaturated fatty acids) and water-soluble components (vitamin C and various phenolics) acting synergistically, and their beneficial effects are seen. The MIND diet is a diet that emerged for this purpose. It was created as a result of the modification of the Mediterranean diet and the DASH diet (Dietary Approaches to Stop Hypertension). In this review, the content of the MIND diet and its relationship with various diseases are included.

Anahtar Kelimeler

Dementia, Mediterranean diet, DASH diet, MIND diet

DEMANSA KARŞI KORUMADA BESLENMENİN ETKİSİ: NÖRODEJENERATİF GECİKME MÜDAHALESİ DİYETİ

Öz

Demans gibi yaşa bağlı hastalıkların oranları her sene artmaktadır. Membran yapısının ve fonksiyonunun korunması yaşlanma sırasında nörodejenerasyonun önlenmesi ve optimal beyin fonksiyonunun desteklenmesi açısından önemlidir. Farklı diyet mikro besin sınıflarının sinerjik etkisinin membran yapısını ve işlevini desteklemede egzersiz ve stres azaltmadan daha fazla sinerjik katkı sağladığı görülmüştür. Membran akışkanlığını korumak ve kronik inflamasyonu önlemek için diyet mikro besinleri incelenmiştir. Sinerjistik olarak hareket eden membranda çözünen bileşenlere (zeaksantin, lutein, vitamin E ve omega-3, çoklu doymamış yağ asitleri) ve suda çözünen bileşenlere (C vitamini ve çeşitli fenolikler) odaklanılmış ve yararlı etkileri görülmüştür. MIND diyeti de bu amaçla ortaya çıkmıştır. Akdeniz diyeti ile DASH diyetinin (Hipertansiyonu Durdurmak için Beslenme Yaklaşımı) modifikasyonu sonucu oluşturulmuştur. Bu derlemede MIND diyetinin içeriğine ve çeşitli hastalıklarla ilişkisi hakkında yapılan çalışmalara yer verilmiştir.

Anahtar Kelimeler

Demans, Akdeniz diyeti, DASH diyet, MIND diyet

Kaynakça

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