Natural treatment approaches for varicose veins: A brief review of the literature

Tuğsen Büyükyıldırım; Fatma Sezer Şenol Deniz

doi:10.23902/trkjnat.1411314

Review

Natural treatment approaches for varicose veins: A brief review of the literature

Year 2024, Volume: 25 Issue: 1, 121 - 132, 15.04.2024

Tuğsen Büyükyıldırım , Fatma Sezer Şenol Deniz

https://doi.org/10.23902/trkjnat.1411314

Abstract

Chronic venous insufficiency (CVI) is a widespread condition affecting millions worldwide. Each year, approximately 150,000 new patients are diagnosed with CVI, and nearly $500 million is used in the care of these patients. The venous system has sturdy valves and muscle pumps that keep blood flowing back to the heart against gravity. The inadequacy of these systems leads to difficulties in blood circulation, blood pooling, and venous hypertension, all which have the potential to lead to the development of varicose veins, edema, discomfort, alterations in the skin, and potentially even the formation of ulcers. Conditions that induce CVI are genetic predisposition, obesity (body mass index greater than 30), continuous standing/sitting work, age, pregnancy, gender, and lifestyle. Conventional venous insufficiency treatments include compression therapy, surgical interventions like vein stripping, and sclerotherapy. Venoactive drugs used in conservative treatment have the potential to enhance both varicose veins and symptoms associated with chronic venous disorders throughout all stages of venous insufficiency. In addition to synthetic drugs, naturally derived coumarins, flavonoids, rutin derivatives, pycnogenol, micronized purified flavonoid fraction, and saponosides are essential in the treatment. Medicinal plants and natural compounds are highly preferred for treating CVI and varicose veins due to their biological activities, such as anti-inflammatory, antioxidant, and vascular tone improvement. The present review provides a concise overview of the utilization of natural compounds and plant extracts in treating varicose veins, both in medical practice and traditional folk medicine.

Keywords

Varicose vein, ethnobotanical, medicinal plants, natural compounds

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Year 2024, Volume: 25 Issue: 1, 121 - 132, 15.04.2024

Tuğsen Büyükyıldırım , Fatma Sezer Şenol Deniz

https://doi.org/10.23902/trkjnat.1411314

Abstract

Kronik venöz yetmezlik (KVY), dünya çapında milyonlarca kişiyi etkileyen yaygın bir durumdur. Her yıl yaklaşık 150.000 yeni hastaya KVY tanısı konulur ve bu hastaların bakımına yaklaşık 500 milyon dolar harcanmaktadır. Venöz sistemde, kanın yer çekimine karşı kalbe geri akmasını sağlayacak sağlam kapakçıklar ve kas pompaları vardır. Bu sistemlerin yetersizliği kan dolaşımında zorluklara yol açarak kanın birikmesine ve venöz hipertansiyona neden olur. Yukarıda belirtilen durum varisli damarların gelişmesine, ödeme, ciltte değişikliklere ve hatta potansiyel olarak ülser oluşumuna yol açabilir. KVY genetik yatkınlığını tetikleyen koşullar arasında, obezite (vücut kitle indeksi 30'dan büyük), sürekli ayakta/oturup çalışma, yaş, hamilelik, cinsiyet ve yaşam tarzı yer almaktadır. Geleneksel venöz yetmezlik tedavileri arasında kompresyon tedavisi, damar soyulması gibi cerrahi müdahaleler ve skleroterapi yer alır. Konservatif tedavide kullanılan venoaktif ilaçlar, hem varisli damarları hem de venöz yetmezliğin tüm aşamalarında kronik venöz bozukluklarla ilişkili semptomları iyileştirme potansiyeline sahiptir. Tedavide sentetik ilaçların yanı sıra doğal olarak elde edilen kumarinler, flavonoitler, rutin türevleri, piknogenol, mikronize saflaştırılmış flavonoit fraksiyonu ve saponozitler önemlidir. Tıbbi bitkiler ve doğal bileşikler, anti-enflamatuvar, antioksidan ve damar tonusunu iyileştirme gibi biyolojik aktivitelerinden dolayı KVY ve varisli damarların tedavisinde oldukça tercih edilmektedir. Bu derleme, hem tıbbi uygulamada hem de geleneksel halk hekimliğinde varisli damarların tedavisinde doğal bileşiklerin ve bitki esktrelerinin kullanımına kısa bir genel bakış sunmaktadır.

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There are 107 citations in total.

Details

Primary Language	English
Subjects	Pharmacognosy
Journal Section	Review/Derleme
Authors	Tuğsen Büyükyıldırım 0000-0003-0101-9742 Fatma Sezer Şenol Deniz 0000-0002-5850-9841
Early Pub Date	April 4, 2024
Publication Date	April 15, 2024
Submission Date	December 28, 2023
Acceptance Date	March 30, 2024
Published in Issue	Year 2024 Volume: 25 Issue: 1

Cite

APA	Büyükyıldırım, T., & Şenol Deniz, F. S. (2024). Natural treatment approaches for varicose veins: A brief review of the literature. Trakya University Journal of Natural Sciences, 25(1), 121-132. https://doi.org/10.23902/trkjnat.1411314
AMA	Büyükyıldırım T, Şenol Deniz FS. Natural treatment approaches for varicose veins: A brief review of the literature. Trakya Univ J Nat Sci. April 2024;25(1):121-132. doi:10.23902/trkjnat.1411314
Chicago	Büyükyıldırım, Tuğsen, and Fatma Sezer Şenol Deniz. “Natural Treatment Approaches for Varicose Veins: A Brief Review of the Literature”. Trakya University Journal of Natural Sciences 25, no. 1 (April 2024): 121-32. https://doi.org/10.23902/trkjnat.1411314.
EndNote	Büyükyıldırım T, Şenol Deniz FS (April 1, 2024) Natural treatment approaches for varicose veins: A brief review of the literature. Trakya University Journal of Natural Sciences 25 1 121–132.
IEEE	T. Büyükyıldırım and F. S. Şenol Deniz, “Natural treatment approaches for varicose veins: A brief review of the literature”, Trakya Univ J Nat Sci, vol. 25, no. 1, pp. 121–132, 2024, doi: 10.23902/trkjnat.1411314.
ISNAD	Büyükyıldırım, Tuğsen - Şenol Deniz, Fatma Sezer. “Natural Treatment Approaches for Varicose Veins: A Brief Review of the Literature”. Trakya University Journal of Natural Sciences 25/1 (April 2024), 121-132. https://doi.org/10.23902/trkjnat.1411314.
JAMA	Büyükyıldırım T, Şenol Deniz FS. Natural treatment approaches for varicose veins: A brief review of the literature. Trakya Univ J Nat Sci. 2024;25:121–132.
MLA	Büyükyıldırım, Tuğsen and Fatma Sezer Şenol Deniz. “Natural Treatment Approaches for Varicose Veins: A Brief Review of the Literature”. Trakya University Journal of Natural Sciences, vol. 25, no. 1, 2024, pp. 121-32, doi:10.23902/trkjnat.1411314.
Vancouver	Büyükyıldırım T, Şenol Deniz FS. Natural treatment approaches for varicose veins: A brief review of the literature. Trakya Univ J Nat Sci. 2024;25(1):121-32.

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