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Some Properties of Royal Jelly a Functional Beekeeping Product and its Health Effects

Year 2023, Volume: 23 Issue: 1, 138 - 152, 19.05.2023
https://doi.org/10.31467/uluaricilik.1275691

Abstract

Royal jelly, secreted from the hypopharyngeal and mandibular glands of worker honeybees, is a natural beekeeping product with a whitish colour, distinctive odour, sour-sweet taste, and viscous structure. It has a high nutritional value because it contains various carbohydrates, proteins, essential amino acids, lipids, fatty acids, B group vitamins, vitamins A, C, D, and E, and minerals such as potassium, calcium, sodium, magnesium, and phenolic compounds. It has antimicrobial, antioxidant, antiinflammatory, antidiabetic, anticancer, and antihypertensive effects and many positive effects on the immune, nervous, and digestive systems because of its rich bioactive contents. For this reason, its consumption is preferred by society as a supplementary food and can be consumed directly in the form of royal jelly or honey, pollen, or propolis mixtures. This study was carried out to review information about some physical, sensorial, and chemical properties of royal jelly, its effects on health, and its consumption as a food.

References

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  • Bíliková K, Mirgorodskaya E, Bukovská G, Gobom J, Lehrach H, Šimúth J. Towards functional proteomics of minority component of honeybee royal jelly: The effect of post‐translational modifications on the antimicrobial activity of apalbumin2. Proteomics, 2009, 9(8): 2131-2138.
  • Caixeta DC, Teixeira RR, Peixoto LG, Machado HL, Baptista NB, de Souza AV, Vilela DD, Franci CR, Salmen Espindola, F. Adaptogenic potential of royal jelly in liver of rats exposed to chronic stress. PloS One, 2018, 13(1): e0191889.
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  • El-Guendouz S, Lyoussi B, Miguel MG. Insight into the chemical composition and biological properties of Mediterranean royal jelly. J Apic Res, 2020a, 59(5), 890-909.
  • El-Guendouz S, Machado AM, Aazza S, Lyoussi B, Miguel MG, Mateus MC, Figueiredo, AC. Chemical characterization and biological properties of royal jelly samples from the Mediterranean area. Nat Prod Commun, 2020b, 15(2): 1934578X20908080.
  • Emir M. Effect of harvesting period on chemical and bioactive properties of royal jelly from Turkey. Eur Food Sci Eng, 2020, 1(1): 9-12.
  • Escamilla KIA, Ordóñez YBM, Sandoval-Peraza VM, Fernández JJA, Ancona DAB. Anti-hypertensive activity in vitro and in vivo on royal jelly produced by different diets. Emir J Food Agr, 2022, 34(1): 9-15.
  • Fan P, Han B, Hu H, Wei Q, Zhang X, Meng L, Nie J, Tang X, Tian X, Zhang L, Wang L, Li J. Proteome of thymus and spleen reveals that 10-hydroxydec-2-enoic acid could enhance immunity in mice. Expert Opin Ther Targets, 2020, 24(3): 267-279.
  • Fratini F, Cilia G, Mancini S, Felicioli A. Royal Jelly: An ancient remedy with remarkable antibacterial properties. Microbiol Res, 2016, 192: 130-141.
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FONKSİYONEL BİR ARICILIK ÜRÜNÜ OLAN ARI SÜTÜNÜN BAZI ÖZELLİKLERİ ve SAĞLIK ÜZERİNE ETKİLERİ

Year 2023, Volume: 23 Issue: 1, 138 - 152, 19.05.2023
https://doi.org/10.31467/uluaricilik.1275691

Abstract

İşçi bal arılarının hipofaringeal ve mandibular bezlerinden salgılanan arı sütü beyazımsı renkte, kendine özgü kokuda, ekşimsi tatlı bir tatta ve viskoz yapıda olan doğal bir arıcılık ürünüdür. Yapısında çeşitli karbonhidratlar, proteinler, esansiyel aminoasitler, lipitler, yağ asitleri, B grubu vitaminleri ile A, C, D ve E vitaminleri, potasyum, kalsiyum, sodyum, magnezyum gibi mineraller ve fenolik bileşikler bulunması nedeniyle arı sütünün besin değeri yüksektir. Arı sütünün sahip olduğu bu zengin biyoaktif bileşik içeriği sayesinde antimikrobiyal, antioksidan, antiinflamatuar, antidiyabetik, antikanser ve antihipertansif etkiler ile bağışıklık, sinir ve sindirim sistemleri üzerine birçok olumlu etkileri bulunmaktadır. Bu nedenle toplumun farklı kesimleri tarafından doğrudan arı sütü şeklinde veya bal, polen veya propolis karışımları halinde takviye gıda olarak tüketimi tercih edilmektedir. Bu çalışma arı sütünün bazı fiziksel, duyusal ve kimyasal özellikleri, sağlık üzerine etkileri ve gıda olarak tüketimi ile ilgili bilgilerin derlenmesi amacıyla gerçekleştirilmiştir.

References

  • Abandansari RM, Parsian H, Kazerouni F, Porbagher R, Zabihi E, Rahimipour A. Effect of simultaneous treatment with royal jelly and doxorubicin on the survival of the prostate cancer cell line (PC3): an in vitro study. Int J Cancer Manag, 2018, 11: e13780.
  • Abdelsalam HM, Diab AA, Hussien AG, Helmi SM, Aziz JA. Ginseng and royal jelly diminish diabetic hepato-and nephrotoxicity in STZ-induced diabetic male rats. Nutrire, 2023, 48(1): 8.
  • Abu-Serie MM, Habashy NH. Two purified proteins from royal jelly with in vitro dual anti-hepatic damage potency: Major royal jelly protein 2 and its novel isoform X1. Int J Biol Macromol, 2019, 128: 782-795.
  • Ahmad S, Campos MG, Fratini F, Altaye SZ, Li J. New insights into the biological and pharmaceutical properties of royal jelly. Int J Mol Sci, 2020, 21(2): 382.
  • Alnomasy SF, Al Shehri ZS. Anti-cancer and cell toxicity effects of royal jelly and its cellular mechanisms against human hepatoma cells. Pharmacogn Mag, 2022, 18(79): 635-640.
  • Anonim. TS 6666/2000 ve T1/2010 Arı sütü standardı. Türk Standardları Enstitüsü, 24 Haziran 2010 kabul tarihli standart, Ankara.
  • Anonymous. ISO 12824 international royal jelly standard. 15/09/2016, https://standards.iteh.ai/catalog/standards/sist/59729cd3-3d97-41c6-b828-32d63f914334/iso-12824-2016.
  • Altaye SZ, Meng L, Li J. Molecular insights into the enhanced performance of royal jelly secretion by a stock of honeybee (Apis mellifera ligustica) selected for increasing royal jelly production. Apidologie, 2019, 50: 436-453.
  • Alu'datt MH, Rababah T, Obaidat MM, Ereifej K, Alhamad MN, Mhaidat N, Andrade JE, Johargy A, Ayadi W. Probiotics in milk as functional food: characterization and nutraceutical properties of extracted phenolics and peptides from fermented skimmed milk inoculated with royal jelly. J Food Saf, 2015, 35(4): 509-522.
  • Ayna A, Tunc A, Özbolat SN, Bengü AŞ, Aykutoğlu G, Canli D, Polat R, Çiftci M, Darendelioğlu E. Anticancer, and antioxidant activities of royal jelly on HT-29 colon cancer cells andmelissopalynological analysis. Turk J Bot, 2021, 45(8): 809-819.
  • Bagameri L, Baci GM, Dezmirean DS. Royal jelly as a nutraceutical natural product with a focus on its antibacterial activity. Pharmaceutics, 2022, 14(6): 1142.
  • Bălan A, Moga MA, Dima L, Toma S, Elena Neculau A, Anastasiu, CV. Royal jelly-A traditional and natural remedy for postmenopausal symptoms and aging-related pathologies. Molecules, 2020, 25(14): 3291.
  • Balkanska R, Mladenova E, Karadjova I. Quantification of selected trace and mineral elements in royal jelly from Bulgaria by ICP-OES and etaas. J Apic Sci, 2017, 61(2): 223-232.
  • Bărnuţiu LI, Mărghitaş LA, Dezmirean DS, Mihai CM, Bobiş O. Chemical composition and antimicrobial activity of Royal Jelly-Review. Sci P Anim Sci Biotechnol, 2011, 44(2): 67-72.
  • Bazeyad AY, Al-Ghamdi AA, Alattal YZ. Physicochemical characteristics of local royal jelly produced in Al-Baha region, Saudi Arabia. World J Adv Res Rev, 2022, 14: 284-292.
  • Bíliková K, Mirgorodskaya E, Bukovská G, Gobom J, Lehrach H, Šimúth J. Towards functional proteomics of minority component of honeybee royal jelly: The effect of post‐translational modifications on the antimicrobial activity of apalbumin2. Proteomics, 2009, 9(8): 2131-2138.
  • Caixeta DC, Teixeira RR, Peixoto LG, Machado HL, Baptista NB, de Souza AV, Vilela DD, Franci CR, Salmen Espindola, F. Adaptogenic potential of royal jelly in liver of rats exposed to chronic stress. PloS One, 2018, 13(1): e0191889.
  • Chen D, Guo C, Lu W, Zhang C, Xiao C. Rapid quantification of royal jelly quality by mid-infrared spectroscopy coupled with backpropagation neural network. Food Chem, 2023, 418: 135996.
  • Civelek İ. Biological activities of royal jelly: a mini-review. Anatol J Biol, 2022, 3(1): 1-8.
  • Collazo N, Carpena M, Nuñez-Estevez B, Otero P, Simal-Gandara J, Prieto MA. Health promoting properties of bee royal jelly: Food of the queens. Nutrients, 2021, 13(2): 543.
  • Çelik S, Gerçek YC, Özkök A, Ecem Bayram N. Organic acids and their derivatives: minor components of bee pollen, bee bread, royal jelly and bee venom. Eur Food Res Technol, 2022, 248(12): 3037-3057.
  • Damico ME, Rueppell O, Shaffer Z, Han B, Raymann K. High royal jelly production does not impact the gut microbiome of honeybees. Animal Microbiome, 2021, 3(1): 1-11.
  • Ecem Bayram N, Cebi N, Celik S, Gercek YC, Bayram S, Tanuğur Samancı AE, Sağdıç O, Özkök A. Turkish royal jelly: amino acid, physicochemical, antioxidant, multi-elemental, antibacterial and fingerprint profiles by analytical techniques combined with chemometrics. J Apicult Res, 2021, 60(5): 751-764.
  • El-Guendouz S, Lyoussi B, Miguel MG. Insight into the chemical composition and biological properties of Mediterranean royal jelly. J Apic Res, 2020a, 59(5), 890-909.
  • El-Guendouz S, Machado AM, Aazza S, Lyoussi B, Miguel MG, Mateus MC, Figueiredo, AC. Chemical characterization and biological properties of royal jelly samples from the Mediterranean area. Nat Prod Commun, 2020b, 15(2): 1934578X20908080.
  • Emir M. Effect of harvesting period on chemical and bioactive properties of royal jelly from Turkey. Eur Food Sci Eng, 2020, 1(1): 9-12.
  • Escamilla KIA, Ordóñez YBM, Sandoval-Peraza VM, Fernández JJA, Ancona DAB. Anti-hypertensive activity in vitro and in vivo on royal jelly produced by different diets. Emir J Food Agr, 2022, 34(1): 9-15.
  • Fan P, Han B, Hu H, Wei Q, Zhang X, Meng L, Nie J, Tang X, Tian X, Zhang L, Wang L, Li J. Proteome of thymus and spleen reveals that 10-hydroxydec-2-enoic acid could enhance immunity in mice. Expert Opin Ther Targets, 2020, 24(3): 267-279.
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Details

Primary Language Turkish
Subjects Food Engineering, Agricultural Engineering (Other), Traditional, Complementary and Integrative Medicine
Journal Section Review
Authors

Gülizar Mutlu 0009-0004-4757-5693

Doğa Akbulut 0009-0006-9248-2239

Nurten Seha Aydın 0009-0008-8938-0295

Ceren Mutlu 0000-0003-4943-2798

Publication Date May 19, 2023
Acceptance Date April 26, 2023
Published in Issue Year 2023 Volume: 23 Issue: 1

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Vancouver Mutlu G, Akbulut D, Aydın NS, Mutlu C. FONKSİYONEL BİR ARICILIK ÜRÜNÜ OLAN ARI SÜTÜNÜN BAZI ÖZELLİKLERİ ve SAĞLIK ÜZERİNE ETKİLERİ. U. Arı. D.-U. Bee J. 2023;23(1):138-52.

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