Changing of Hemoglobin A1c Affects Mean Platelet Volume in Type-2 Diabetes Mellitus

Year 2016, Volume: 2 Issue: 1, 27 - 35, 01.01.2016

Huseyin Kurt , Davut Demirkiran

https://doi.org/10.5455/umj.20160211122820

Abstract

Background: Mean platelet volume MPV level is known to increase in diabetes mellitus DM . Objective: In this study, the first aim is to examine whether there is a correlation between MPV and hemoglobin A1c HbA1c and fasting plasma glucose FPG . The second aim is to investigate whether a correlation exists between MPV and HbA1c and FPG changes after treatment Method: In the study, we examined baseline and final HbA1c, MPV and FPGA values of 343 patients. Including the study group SG consisted of 169 patients with diabetes whose HbA1c levels decreased %1 and the control group involving 174 patients whose HbA1c levels did not change. Results: Similar to CG, HbA1c level of SG decreased to 7.58, and MPV level reduced to 8.68. There existed a positive correlation between MPV and HbA1c levels r=154; p

Keywords

Mean platelet volume, diabetes mellitus, hemoglobin A1c, fasting plasma glucose.

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