The Effect of Varenicline, Nicotine Replacement, and Acupuncture for Smoking Cessation

Year 2023, Volume: 3 Issue: 3, 554 - 565, 21.12.2023

Habibe İnci , Fatih İnci , Didem Adahan

Abstract

Aim: Various methods are used in the treatment of cigarette addiction. It was aimed to compare the smoking cessation status of patients who applied for smoking cessation treatment and received varenicline treatment, nicotine replacement therapy (NRT), and acupuncture treatment.
Methods: In the study, 402 individuals who received varenicline treatment, NRT, and acupuncture treatment for smoking cessation were included. The sociodemographic data of the individuals, the results of the Fagerström nicotine dependence test, and the data on smoking cessation obtained during the 6 months after the treatment were retrospectively scanned from the patient files.
Results: Of the 402 individuals included in the study, 60.4% (n = 243) were treated with varenicline, 28.1% (n = 113) received NRT, and 11.4% (n = 46) were treated with acupuncture. 63.4% (n = 255) of all the patients, 71.2% (n = 173) of the patients treated with varenicline, 56.6% (n = 64) of the patients who received NRT, and 39.1% (n = 18) of the patients treated with acupuncture quit smoking. It was found that smoking cessation rate was higher in the patients treated with varenicline compared to other treatments (p <0.001), and varenicline was more effective than other treatments in very high addiction (p <0.001).
Conclusion: Varenicline treatment, NRT, and acupuncture treatment are all effective methods for smoking cessation. Varenicline treatment is more effective in smoking cessation than other treatments, and this efficiency is higher than other treatments in very high addiction.

Keywords

Smoking cessation, Varenicline, Nicotine replacement therapy, Acupuncture

Ethical Statement

Approved by Karabük University Non-Interventional Ethics Committee (Approval No: 2020/211, 14/05/2020)

Supporting Institution

none

Project Number

yok

Thanks

none

Sigarayı Bırakmada Vareniklin, Nikotin Replasmanı ve Akupunkturun Etkisi

Abstract

Amaç: Sigara bağımlılığının tedavisinde çeşitli yöntemler kullanılmaktadır. Sigara bırakma tedavisi için başvuran ve vareniklin tedavisi, nikotin replasman tedavisi (NRT) ve akupunktur tedavisi alan hastaların sigarayı bırakma durumlarının karşılaştırılması amaçlandı.
Yöntemler: Çalışmaya vareniklin tedavisi, NRT ve sigarayı bırakma amaçlı akupunktur tedavisi alan 402 kişi dahil edildi. Bireylerin sosyodemografik verileri, Fagerström nikotin bağımlılık testi sonuçları ve tedavi sonrası 6 ay içerisinde sigarayı bırakmaya ilişkin veriler hasta dosyalarından geriye dönük olarak tarandı.
Bulgular: Çalışmaya dahil edilen 402 kişinin %60,4'ü (n=243) vareniklin, %28,1'i (n=113) NRT ve %11,4'ü (n=46) akupunktur tedavisi aldı. Tüm hastaların %63,4’ü (n=255), vareniklin tedavisi alan hastaların %71,2’si (n=173), NRT alan hastaların %56,6’sı (n=64), akupunktur tedavisi gören hastaların %39,1’i (n=18) sigarayı bıraktı. Vareniklin tedavisi gören hastalarda sigarayı bırakma oranının diğer tedavilere göre daha yüksek olduğu (p<0,001), çok yüksek bağımlılıklarda ise vareniklinin diğer tedavilere göre daha etkili olduğu (p<0,001) belirlendi.
Sonuç: Vareniklin tedavisi, NRT ve akupunktur tedavisi sigarayı bırakmada etkili yöntemlerdir. Vareniklin tedavisi sigarayı bırakmada diğer tedavilere göre daha etkilidir ve çok yüksek bağımlılık durumlarında bu verim diğer tedavilere göre daha yüksektir.

Keywords

Sigarayı bırakma, Vareniklin, Nikotin replasman tedavisi, Akupunktur

Ethical Statement

Karabük Üniversitesi Girişimsel Olmayan Etik Kurul tarafından onaylandı (Onay No: 2020/211, 14/05/2020)

Supporting Institution

yok

Project Number

yok

Thanks

yok

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