THE PHYLOGENETIC RELATIONSHIPS OF LIPASE ENZYMES ACCORDING TO THEIR THERMAL STABILITY BY A COMPUTATIONAL APPROACH

Year 2018, Volume: 1 Issue: 1, 1 - 7, 30.06.2018

Çağın Kandemir Çavaş , Türkan Arıt

Abstract

Molecular
Phylogenetic Analysis studies conducted to reveal the evolutionary
relationships of biological sequences, use two basic methodologies. In the
study of distance-based methodologies, phylogenetic trees were obtained by
clustering Lipase enzymes according to their thermal stability. The biological
sequences to be used in the study were obtained from the NCBI Genbank database.
Methods were coded in the Java programming language and distance matrices were
obtained.  Phylogenetic trees were
constructed using the R language. As a result, Lipase enzymes were effectively
clustered using a distance-based method without alignment, according to their
thermal stability.

Keywords

Molecular Phylogeny, distance based methodology, enzyme clustering

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