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ARUM MACULATUM (YILAN YASTIĞI) BİTKİSİ VE ANTİPARAZİTER ÖZELLİKLERİ

Year 2020, Volume: 11 Issue: 3, 126 - 133, 30.12.2020
https://doi.org/10.38137/vetfarmatoksbulten.753991

Abstract

Arum maculatum geçmişten bugüne insanlar tarafından bilinen bir bitkidir. Bitkinin yumrusu halk arasında özellikle ateş düşürücü, balgam söktürücü ve bağırsak parazitlerinin tedavisi için kullanılmaktadır. Bu derlemenin amacı A. maculatum’un tıbbi kullanımı ve antiparaziter etkileri hakkında bilgi vermektir.

References

  • Abbasi N, Karkondi VR, Asadollahi K, Tahmasebi M, Ghobad A, Taherikalani M, Parisa A. (2014). Analgesic effects of Arum maculatum plant extract in rats compared to other routine analgesics. J Med Plants Res, 8:1025-1030.
  • Alencar VBM, Alencar NMN, Assreuy AMS, Mota ML, Brito GAC, Aragao KS, Bittencourt FS, Pinto VPT, Debray H, Ribeiro RA, Cavada BS. (2005). Pro-inflammatory effect of Arum maculatum lectin and role of resident cells. Int J Biochem Cell Biol, 37:1805-1814.
  • Azab A. (2017). Arum: a plant genus with great medicinal potential. Eur Chem Bull, 6:59-68.
  • Baytop, T. (1984). Türkiye’de bitkilerle tedavi. Sanal Matbaacılık. İstanbul Üniversitesi Yayınları, No:3255.
  • Butschi A, Titz A, Wälti MA, Olieric V, Paschinger K, Nöbauer K, Guo X, Seeberger PH, Wilson IBH, Aebi M, Hengartner MO, Künzler M. (2010). Caenorhabditis elegans N-glycan core beta-galactoside confers sensitivity towards nematotoxic fungal galectin CGL2. PLoS Pathog, 6: e1000717.
  • Colak F, Savaroglu F, Ilhan S. (2009). Antibacterial and antifungal activities of Arum maculatum l. leaves extracts. J Appl Biol Sci, 3:13-16.
  • Colditz IG, Le Jambre LF, Hosse R. (2002). Use of lectin binding characteristics to identify gastrointestinal parasite eggs in feaces. Vet Parasitol, 105:219-227.
  • De Medeiros MLS, De Moura MC, Napoleao TH, Paiva PMG, Coelho LCBB, Bezerra ACDS, Da Silva MDC. (2018). Nematicidal activity of a water soluble lectin from seeds of Moringa oleifera. Int J Biol Macromol, 108:782-789.
  • Demirci S, Ozhatay N. (2012). An ethnobotanical study in Kahramanmaraş (Turkey); wild plants used for medicinal purpose in Andırın, Kahramanmaraş. Turk J Pharm Sci, 9: 75-92.
  • Erbil N, Arslan M, Murathan ZT. (2018). Antioxidant, antimicrobial, and antimutagenic effects and biochemical contents of Arum maculatum l. that ıs a medical plant from Turkish flora. Fresenius Environ Bull, 27:8709-8714.
  • Farahmandfar R, Kenari RE, Asnaashari M, Shahrampour D, Bakhshandeh T. (2019). Bioactive compounds, antioxidant and antimicrobial activities of Arum maculatum leaves extracts as affected by various solvents and extraction methods. Food Sci Nutr, 7:465-475.
  • Frohne D, Pfänder HJ. (2005). Poisonous Plants: A Handbook for Doctors, Pharmacists, Toxicologists, Biologists and Veterinarians. Second Ed, Taylor&Francis, Studgard, Germany.
  • Gibernau M, Macquart D, Przetak G. (2004). Pollination in the Genus Arum – a review. Aroideana, 27:148-166.
  • Grant G. (1999). Plant lectins. In: Caygill, JC, Mueller-Harvey I. (Eds.), Secondary Plant Products: Antinutritional and Beneficial Actions in Animal Feeding, Nottingham University Press, Nottingham, UK, pp. 87–110.
  • Gurocak S, Kupeli B. (2006). Consumption of historical and current phytotherapeutic agents for urolithiasis: a critical review. J Urol, 176: 450-455.
  • Harrison AP, Turfa JM. (2010). Were natural forms of treatment for Fasciola hepatica available to the Etruscans? Int J Med Sci, 7:16-25.
  • Heim C, Hertzberg H, Butschi A, Bleuler-Martinez S, Aebi M, Deplazes P, Künzler M, Stefanic S. (2015). Inhibition of Haemonchus contortus larval development by fungal lectins. Parasit Vectors, 8: 425-435.
  • Kocabaş YZ. (2017). KSÜ Avşar yerleşkesi (Kahramanmaraş) ve çevresi florasının tıbbi bitkileri. Aksaray Univ J Sci Engineer, 1:110-120.
  • Kocaeli Bitkileri (2020). Erişim: [https://kocaelibitkileri.com/arum-maculatum/], Erişim tarihi: 02.05.2020.
  • Kochmarov V, Kozuharova E, Naychov Z, Momekov G, Mincheva I. (2015). Ethnobotany and ethnopharmacology of Arum maculatum l. (Araceae) in Bulgaria with an emphasis on its effect against haemorrhoids. International Journal of Pharmaceutical Chemical and Biological Sciences, 5, 394-402.
  • Küçük M, Akyüz M. (2006). Doğu Karadeniz Bölgesi'nde yetişen tıbbi ve aromatik bitkiler. Erişim: [https://yayin.ogm.gov.tr/yaydepo/1436.pdf], Erişim tarihi: 02.05.2020.
  • Majumder P, Mondal HA, Das S. (2005) Insecticidal activity of Arum maculatum tuber lectin and its binding to the glycosylated insect gut receptors. J Agric Food Chem, 53:6725-6729.
  • Nabeel M, Abderrahman S, Papini A. (2008). Cytogenetic effect of Arum maculatum extract on the bone marrow cells of mice. Caryologia, 61:383-387.
  • Özer Z, Tursun N, Önen H. (2001). Yabancı Otlarla Sağlıklı Yaşam (Gıda ve Tedavi). 4Renk Yayınları, Ankara.
  • Peterson ME, Talcott PA. (2012). Small Animal Toxicology. 3rd ed, Saunders, USA, p.360-726 .
  • Peumans WJ, Van Damme EJM. (1995). Lectins as plant defense proteins. Plant Physiol, 109:347–352.
  • Resmi Gazete. (2019). Erişim [https://www.resmigazete.gov.tr/eskiler/2019/12/20191227-17-1.pdf], Erişim tarihi: 24.04.2020.
  • Rios de Alvarez L, Jackson F, Greer A, Bartley Y, Bartley DJ, Grant G, Huntley JF. (2012a). In vitro screening of plant lectins and tropical plant extracts for anthelmintic properties. Vet Parasitol, 186(3-4): 390-398.
  • Rios de Alvarez L, Jackson F, Greer AW, Grant G, Jackson E, Morrison AA, Huntley JF. (2012b). Direct anthelmintic and immunostimulatory effects of oral dosing semi-purified phytohaemagglutinin lectin in sheep infected with Teladorsagia circumcincta and Trichostrongylus colubriformis. Vet Parasitol, 187:267-274.
  • Quattrrocchi U. (2012). CRC World Dictionary of Medicinal and Poisonous Plants. Common Names, Scientific Names, Eponyms, Synonyms, and Etymology. CRC Press, Boca Raton.
  • Safari E , Amiri M, Bahador A , Amiri M, Esmaeili D. (2014). The study of antibacterial effects of alcoholic extracts of Arum maculatum, Allium hirtifolium and Teucrium polium against nosocomial resistance bacteria. Int J Curr Microbiol App Sci, 3:601-605.
  • Salles HO, Braga Ac, Nascimento MT, Sousa AM, Lima AR, Vieira L da S, Cavalcante AC, Egito AS, Andrade LB (2014). Lectin, hemolysin and protease inhibitors in seed fractions with ovicidal activity against Haemonchus contortus. Revista Bras Parasitol Vet, 23:136-143.
  • Silva RRS, Silva CR, Santos VF, Barbosa CRS, Muniz DF, Santos ALE, Santos MHC, Rocha BAM, Batista KLR, Costa-Júnior LM, Coutinho HDM, Teixeira CS. (2019). Parkia platycephala lectin enhances the antibiotic activity against multi-resistant bacterial strains and inhibits the development of Haemonchus contortus. Microb Pathog, 135:103629.
  • Soares AMDS, Wanderley LF, Costa Junior LM. (2019). The potential of plant and fungal proteins in the control of gastrointestinal nematodes from animals. Rev Bras Parasitol Vet, 28:339-345.
  • Sowter FA. (1949). Arum maculatum L. J Ecol, 37:207-219.
  • Şimşek Yurt N, Türe E, Çubukçu M. (2019). Nivik otu zehirlenmesi: Arum maculatum - Bir Olgu Sunumu. Ankara Med J, 4:796-799.
  • Türkiye Herboloji Derneği. (2020). Arum maculatum. Erişim: [http://www.turkiyeherboloji.org.tr/upload/File/YabanciOt/2-ARUMA.pdf], Erişim tarihi: 24.04.2020.
  • Uzun E, Sariyar G, Adsersen A, Karakoc B, Otuk G, Oktayoglu E, Pirildar S. (2004). Traditional medicine in Sakarya province (Turkey) and antimicrobial activities of selected species, J Ethnopharmacol, 95:287–296.
  • Üçer M. (2010). Sivas yöresinde yerel bitkilerden yapılan ilaçlar, Bitkilerle Tedavi Sempozyumu, 5-6 Haziran 2010 Zeytinburnu, İstanbul: Merkezefendi Geleneksel Tıp Derneği.
  • Van Damme EJM, Coossens K, Smeets K, Van Leuven F, Verhaert P, Peumans WJ. (1995). The major tuber storage protein of Araceae species 1s a lectin’ characterization and molecular cloning of the lectin from Arum maculatum L. Plant Physiol, 107:1147-1158.

ARUM MACULATUM (CUCKOO-PINT) AND ITS ANTIPARASITIC CHARACTERISTICS

Year 2020, Volume: 11 Issue: 3, 126 - 133, 30.12.2020
https://doi.org/10.38137/vetfarmatoksbulten.753991

Abstract

Arum maculatum is a plant known to humans from past to present. The tuber of the plant is used among the people especially for the treatment of antipyretic, expectorant, and intestinal parasites. The purpose of this review is to provide information on the medical use and antiparasitic effects of A. maculatum.

References

  • Abbasi N, Karkondi VR, Asadollahi K, Tahmasebi M, Ghobad A, Taherikalani M, Parisa A. (2014). Analgesic effects of Arum maculatum plant extract in rats compared to other routine analgesics. J Med Plants Res, 8:1025-1030.
  • Alencar VBM, Alencar NMN, Assreuy AMS, Mota ML, Brito GAC, Aragao KS, Bittencourt FS, Pinto VPT, Debray H, Ribeiro RA, Cavada BS. (2005). Pro-inflammatory effect of Arum maculatum lectin and role of resident cells. Int J Biochem Cell Biol, 37:1805-1814.
  • Azab A. (2017). Arum: a plant genus with great medicinal potential. Eur Chem Bull, 6:59-68.
  • Baytop, T. (1984). Türkiye’de bitkilerle tedavi. Sanal Matbaacılık. İstanbul Üniversitesi Yayınları, No:3255.
  • Butschi A, Titz A, Wälti MA, Olieric V, Paschinger K, Nöbauer K, Guo X, Seeberger PH, Wilson IBH, Aebi M, Hengartner MO, Künzler M. (2010). Caenorhabditis elegans N-glycan core beta-galactoside confers sensitivity towards nematotoxic fungal galectin CGL2. PLoS Pathog, 6: e1000717.
  • Colak F, Savaroglu F, Ilhan S. (2009). Antibacterial and antifungal activities of Arum maculatum l. leaves extracts. J Appl Biol Sci, 3:13-16.
  • Colditz IG, Le Jambre LF, Hosse R. (2002). Use of lectin binding characteristics to identify gastrointestinal parasite eggs in feaces. Vet Parasitol, 105:219-227.
  • De Medeiros MLS, De Moura MC, Napoleao TH, Paiva PMG, Coelho LCBB, Bezerra ACDS, Da Silva MDC. (2018). Nematicidal activity of a water soluble lectin from seeds of Moringa oleifera. Int J Biol Macromol, 108:782-789.
  • Demirci S, Ozhatay N. (2012). An ethnobotanical study in Kahramanmaraş (Turkey); wild plants used for medicinal purpose in Andırın, Kahramanmaraş. Turk J Pharm Sci, 9: 75-92.
  • Erbil N, Arslan M, Murathan ZT. (2018). Antioxidant, antimicrobial, and antimutagenic effects and biochemical contents of Arum maculatum l. that ıs a medical plant from Turkish flora. Fresenius Environ Bull, 27:8709-8714.
  • Farahmandfar R, Kenari RE, Asnaashari M, Shahrampour D, Bakhshandeh T. (2019). Bioactive compounds, antioxidant and antimicrobial activities of Arum maculatum leaves extracts as affected by various solvents and extraction methods. Food Sci Nutr, 7:465-475.
  • Frohne D, Pfänder HJ. (2005). Poisonous Plants: A Handbook for Doctors, Pharmacists, Toxicologists, Biologists and Veterinarians. Second Ed, Taylor&Francis, Studgard, Germany.
  • Gibernau M, Macquart D, Przetak G. (2004). Pollination in the Genus Arum – a review. Aroideana, 27:148-166.
  • Grant G. (1999). Plant lectins. In: Caygill, JC, Mueller-Harvey I. (Eds.), Secondary Plant Products: Antinutritional and Beneficial Actions in Animal Feeding, Nottingham University Press, Nottingham, UK, pp. 87–110.
  • Gurocak S, Kupeli B. (2006). Consumption of historical and current phytotherapeutic agents for urolithiasis: a critical review. J Urol, 176: 450-455.
  • Harrison AP, Turfa JM. (2010). Were natural forms of treatment for Fasciola hepatica available to the Etruscans? Int J Med Sci, 7:16-25.
  • Heim C, Hertzberg H, Butschi A, Bleuler-Martinez S, Aebi M, Deplazes P, Künzler M, Stefanic S. (2015). Inhibition of Haemonchus contortus larval development by fungal lectins. Parasit Vectors, 8: 425-435.
  • Kocabaş YZ. (2017). KSÜ Avşar yerleşkesi (Kahramanmaraş) ve çevresi florasının tıbbi bitkileri. Aksaray Univ J Sci Engineer, 1:110-120.
  • Kocaeli Bitkileri (2020). Erişim: [https://kocaelibitkileri.com/arum-maculatum/], Erişim tarihi: 02.05.2020.
  • Kochmarov V, Kozuharova E, Naychov Z, Momekov G, Mincheva I. (2015). Ethnobotany and ethnopharmacology of Arum maculatum l. (Araceae) in Bulgaria with an emphasis on its effect against haemorrhoids. International Journal of Pharmaceutical Chemical and Biological Sciences, 5, 394-402.
  • Küçük M, Akyüz M. (2006). Doğu Karadeniz Bölgesi'nde yetişen tıbbi ve aromatik bitkiler. Erişim: [https://yayin.ogm.gov.tr/yaydepo/1436.pdf], Erişim tarihi: 02.05.2020.
  • Majumder P, Mondal HA, Das S. (2005) Insecticidal activity of Arum maculatum tuber lectin and its binding to the glycosylated insect gut receptors. J Agric Food Chem, 53:6725-6729.
  • Nabeel M, Abderrahman S, Papini A. (2008). Cytogenetic effect of Arum maculatum extract on the bone marrow cells of mice. Caryologia, 61:383-387.
  • Özer Z, Tursun N, Önen H. (2001). Yabancı Otlarla Sağlıklı Yaşam (Gıda ve Tedavi). 4Renk Yayınları, Ankara.
  • Peterson ME, Talcott PA. (2012). Small Animal Toxicology. 3rd ed, Saunders, USA, p.360-726 .
  • Peumans WJ, Van Damme EJM. (1995). Lectins as plant defense proteins. Plant Physiol, 109:347–352.
  • Resmi Gazete. (2019). Erişim [https://www.resmigazete.gov.tr/eskiler/2019/12/20191227-17-1.pdf], Erişim tarihi: 24.04.2020.
  • Rios de Alvarez L, Jackson F, Greer A, Bartley Y, Bartley DJ, Grant G, Huntley JF. (2012a). In vitro screening of plant lectins and tropical plant extracts for anthelmintic properties. Vet Parasitol, 186(3-4): 390-398.
  • Rios de Alvarez L, Jackson F, Greer AW, Grant G, Jackson E, Morrison AA, Huntley JF. (2012b). Direct anthelmintic and immunostimulatory effects of oral dosing semi-purified phytohaemagglutinin lectin in sheep infected with Teladorsagia circumcincta and Trichostrongylus colubriformis. Vet Parasitol, 187:267-274.
  • Quattrrocchi U. (2012). CRC World Dictionary of Medicinal and Poisonous Plants. Common Names, Scientific Names, Eponyms, Synonyms, and Etymology. CRC Press, Boca Raton.
  • Safari E , Amiri M, Bahador A , Amiri M, Esmaeili D. (2014). The study of antibacterial effects of alcoholic extracts of Arum maculatum, Allium hirtifolium and Teucrium polium against nosocomial resistance bacteria. Int J Curr Microbiol App Sci, 3:601-605.
  • Salles HO, Braga Ac, Nascimento MT, Sousa AM, Lima AR, Vieira L da S, Cavalcante AC, Egito AS, Andrade LB (2014). Lectin, hemolysin and protease inhibitors in seed fractions with ovicidal activity against Haemonchus contortus. Revista Bras Parasitol Vet, 23:136-143.
  • Silva RRS, Silva CR, Santos VF, Barbosa CRS, Muniz DF, Santos ALE, Santos MHC, Rocha BAM, Batista KLR, Costa-Júnior LM, Coutinho HDM, Teixeira CS. (2019). Parkia platycephala lectin enhances the antibiotic activity against multi-resistant bacterial strains and inhibits the development of Haemonchus contortus. Microb Pathog, 135:103629.
  • Soares AMDS, Wanderley LF, Costa Junior LM. (2019). The potential of plant and fungal proteins in the control of gastrointestinal nematodes from animals. Rev Bras Parasitol Vet, 28:339-345.
  • Sowter FA. (1949). Arum maculatum L. J Ecol, 37:207-219.
  • Şimşek Yurt N, Türe E, Çubukçu M. (2019). Nivik otu zehirlenmesi: Arum maculatum - Bir Olgu Sunumu. Ankara Med J, 4:796-799.
  • Türkiye Herboloji Derneği. (2020). Arum maculatum. Erişim: [http://www.turkiyeherboloji.org.tr/upload/File/YabanciOt/2-ARUMA.pdf], Erişim tarihi: 24.04.2020.
  • Uzun E, Sariyar G, Adsersen A, Karakoc B, Otuk G, Oktayoglu E, Pirildar S. (2004). Traditional medicine in Sakarya province (Turkey) and antimicrobial activities of selected species, J Ethnopharmacol, 95:287–296.
  • Üçer M. (2010). Sivas yöresinde yerel bitkilerden yapılan ilaçlar, Bitkilerle Tedavi Sempozyumu, 5-6 Haziran 2010 Zeytinburnu, İstanbul: Merkezefendi Geleneksel Tıp Derneği.
  • Van Damme EJM, Coossens K, Smeets K, Van Leuven F, Verhaert P, Peumans WJ. (1995). The major tuber storage protein of Araceae species 1s a lectin’ characterization and molecular cloning of the lectin from Arum maculatum L. Plant Physiol, 107:1147-1158.
There are 40 citations in total.

Details

Primary Language Turkish
Subjects Veterinary Sciences
Journal Section Review
Authors

Tugrul Atalay 0000-0002-4225-4071

Kader Yıldız 0000-0001-5802-6156

Publication Date December 30, 2020
Acceptance Date September 19, 2020
Published in Issue Year 2020 Volume: 11 Issue: 3

Cite

APA Atalay, T., & Yıldız, K. (2020). ARUM MACULATUM (YILAN YASTIĞI) BİTKİSİ VE ANTİPARAZİTER ÖZELLİKLERİ. Veteriner Farmakoloji Ve Toksikoloji Derneği Bülteni, 11(3), 126-133. https://doi.org/10.38137/vetfarmatoksbulten.753991