Current classification of Peribunyaviridae family: genetic diversity and contributing factors

Year 2022, Volume: 1 Issue: 2, 42 - 58, 31.12.2022

İlker Şahinkesen , Fırat Doğan , Seval Bılge Dagalp

Abstract

The first detection of Bunyamweravirus in 1943 and many other antigenically related viruses identified in the following years led to the formal establishment of the Bunyaviridae family in 1975. This family became the Bunyavirales order in 2017 following proposals submitted to International Committee on Taxonomy of Viruses when the establishment of the Peribunyaviridae family was also approved for the Orthobunyavirus and Herbertvirus genera. The Peribunyaviridae family includes the Orthobunyavirus, Herbertvirus, Pacuvirus, and Shangavirus genera. Many types of viruses within this family can infect humans, mammals, plants, and insects. However, many of these viruses are transmitted by arthropod vectors without requiring mammals for their viability, which propose that Peribunyaviruses might have initially evolved as viruses that only infect insects. The leading factors contributing to genetic diversity in the Peribunyaviridae family are mutations and genetic reassortment. Mutations are generally detected in the M segment, which encodes the surface glycoproteins that enable viruses to avoid the immune response.

Keywords

Classification, genetic reassortment, mutation, Peribunyaviridae

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