LAMOTRIGİNE INDUCED PROBABLE DRESS SYNDROME: CASE REPORT

Year 2020, Volume: 51 Issue: 3, 168 - 170, 30.09.2020

Nihan Uygur Külcü , Özlem Erdede , Mahmut Doğru Gökçe Ezgi Eraslan Erdal Sarı , Feyza Yıldız

https://doi.org/10.16948/zktipb.613162

Abstract

Drug reaction with
eosinophilia and systemic symptoms (DRESS Syndrome) is a rare,
life-threatening, drug- induced hypersensitivity reaction that include skin
eruptions, hematologic abnormalities (eosinophilia, atypical lymphocytosis),
lymphadenopathy and internal organ involvement (liver, kidney, lung). We
present an adolescent girl with probable DRESS Syndrome who had rash and fever
after having been treated with lamotrigine as antiepileptic drug before
fourteen days.  

LAMOTRİGİNE BAĞLI OLASI DRESS SENDROMU: OLGU SUNUMU

Abstract

DRESS Sendromu (Drug
Rush with Eosinophilia and Systemic Symptoms) ilaç ilişkili döküntü,  hematolojik anormallikler (eozinofili, atipik
lenfositoz), lenfadenopati, iç organ tutulumları (karaciğer, böbrek, akciğer) ile
seyreden nadir, hayatı tehdit edebilen hipersensitivite reaksiyonudur. Antiepileptik
lamotrigin tedavisi başlandıktan on dört gün sonra döküntüsü ve ateşi gelişen
DRESS Sendromu olduğu düşünülen ergen bir kız hastayı sunduk.

Keywords

DRESS Sendromu, ilaç hipersensitivitesi, lamotrigine, çocuk

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