Araştırma Makalesi
BibTex RIS Kaynak Göster
Yıl 2021, Cilt: 3 Sayı: 1, 15 - 19, 22.01.2021
https://doi.org/10.38053/acmj.801894

Öz

Kaynakça

  • Özlü T, Bülbül Y, Ozsu S. Community-acquired pneumonia based on the Turkish national data. Tuberk Toraks 2007; 55: 191-212.
  • Bates JH, Campbell GD, Barron AL, et al. Microbial etiology of acute pneumonia in hospitalized patients. Chest 1992; 101: 1005-12.
  • Fang GD, Fine M, Orloff J, et al. New and emerging etiologies for communityacquired pneumonia with implications for therapy; a prospective multicenter study of 359 cases. Medicine 1990; 69: 307-16.
  • Assicot M, Gendrel D, Carsin H, Raymond J, Guilbaud J, Bohuon C. High serum procalcitonin concentrations in patients with sepsis and infection. Lancet 1993; 341: 515-8.
  • Carrol ED, Thomson AP, Hart CA. Procalcitonin as a marker of sepsis. Int J Antimicrob Agents 2002; 20: 1-9.
  • Shehabi Y, Seppelt I. Pro/Con debate: Is procalcitonin useful for guiding antibiotic decision making in critically ill patients? Critical Care 2008; 12: 211.
  • Thompson D, Pepys MB, Wood SP. The physiological stucture of human C- reactive protein and its complex with phosphocholine. Structure 1999; 7: 169-77.
  • Jilma B, Blann A, Pernerstorfer T, et al. Regulation of adhesion molecules during human endotoxemia. No acute effects of aspirin. Am J Respir Crit Care Med 1999; 159: 857-63.
  • Zahorec R. Ratio of neutrophil to lymphocyte counts-Rapid and simple parameter of systemic inflammation and stress in critically ill. Bratisl Lek Listy 2001; 102: 5-14.
  • Şimşek S, Yurtseven N, Gerçekoğlu H, et al. Ventilator associated pneumonias in a cardiothoracic surgery centre postoperative intensive care unit. J Hosp Infect 2001; 47: 321-4.
  • Aybar M, Topeli A. Dahili yoğun bakım ünitesinde ventilatörle ilişkili pnömoni epidemiyolojisi. Yoğun Bakım Derg 2001; 1: 41- 6.
  • Çevik MA, Yılmaz GR, Erdinç FŞ, et al. Nöroloji Yoğun Bakım Ünitesinde mortalite ile ilişkili faktörler ve nozokomiyal enfeksiyonla mortalitenin ilişkisi. Yoğun Bakım Derg 2001; 1: 47-55.
  • Cazzola M, Centanni S, Blasi F. Have guidelines for the management of community-acquired pneumonia influenced outcomes? Respir Med 2003; 97: 205-11.
  • Sever F, Kömüs N, Esen N, Gündüz AT, Öktem MA, Çımrın AH. Türkiye’de toplum kökenli pnömoni etyoloji ve epidemiyolojisi. Turk Toraks Derg 2013; 14: 5-10.
  • Bircan A, Kaya Ö, Gökırmak M, Öztürk Ö, Sahin Ü, Akkaya A. Toplum kökenli pnömonilerin ağırlığının değerlendirilmesinde C-reaktif protein, lökosit sayısı ve eritrosit sedimentasyon hızının yeri. Tuberk Toraks 2006; 54: 22-9.
  • Fukuyama H, Ishida, Tachibana H, et al. Validation of scoring systems for predicting severe community-acquired pneumonia. Intern Med 2011; 50: 1917-22.
  • Yandiola PPE, Capelastegui A, Quintana J, et al. prospective comparison of severity scores for predicting clinically relevant outcomes for patients hospitalized with community-acquired pneumonia. Chest 2009; 135: 1572-9.
  • Murphy TF, Parameswaran GI. Moraxella catarrhalis, a human respiratory tract pathogen. Clin Infect Dis 2009; 49: 124-31.
  • Bircan A, Sutcu R, Gokırmak M. Total antioxidant capacity and C-reactive protein levels in patients with community-acquired pneumonia. Turk J Med Sci 2008; 38: 537-44.
  • Doruk S, Bulaç S, Sevinç C, Bodur HA, Yilmaz A, Erkorkmaz U. Severity scores and factors related with mortality in cases with community-acquired pneumonia patients in intensive care unit. Tuberk Toraks 2009; 57: 393-400.
  • Aujesky D, Auble TE, Yealy DM, et al. Prospective comparison of three validated prediction rules for prognosis in community-acquired pneumonia. Am J Med 2005; 118: 384-92.
  • Man SY, Lee N, Ip M, et al. Prospective comparison of three predictive rules for assessing severity of community acquired pneumonia in Hong Kong. Thorax 2007; 62: 348-53.
  • Shah BA, Ahmed W, Dhobi GN, Shah NN, Khursheed SQ, Haq I. Validity of pneumonia severity index and CURB-65 severity scoring systems in community acquired pneumonia in an Indian setting. Indian J Chest Dis Allied Sci 2010; 52: 9-17.
  • Monneret G, Labaune JM, Isaac C, Bienvenu F, Putet G, Bienvenu J. Procalcitonin and C-reactive protein levels in neonatal infections. Acta Paediatr 1997; 86: 209-12.

The effect of C-reactive protein, procalcytonine, nuetrophil/lymphosite levels on mortality and duration of hospital stay in pneumonia

Yıl 2021, Cilt: 3 Sayı: 1, 15 - 19, 22.01.2021
https://doi.org/10.38053/acmj.801894

Öz

Aim: The aim of this study is to investigate the effects of procalcitonin (PCT), C-reactive protein (CRP) and neutrophil lymphocyte ratio (NLR) levels on the mortality and duration of hospital stay in patients diagnosed with pneumonia.
Material and Method: The study included 111 cases of pneumonia followed in our chest diseases service and intensive care unit between 2017 and 2018. Collected data included demographic information, NLR, PCT, CURB-65 scores. The data were evaluated by parametric tests (Paired sample T test, Independent sample T test). Correlation between the data was done by Chi-square test. P value <0.05 was considered statistically significant.
Results: A statistically significant positive correlation was detected between PCT and NLR (p <0.001; r = 0.343), PCT and CRP (p <0.001; r = 0.502), NLR and CRP (p <0.001; r = 0.427). There was a statistically significant correlation between mortality and CRP (p <0.001; 0.427), PCT (p <0.001; r = 0.343) and NLR (p = 0.013; r = 0.235). There was a statistically significant correlation between duration of hospital stay and PCT (p = 0.036; r = 0.199) and NLR (p = 0.030; r = 0.206) but not with CRP (p = 0.298; r = 0.102).
Conclusion: Besides PCT and CRP, NLR can also be used for prognosis estimation in pneumonia patients.

Kaynakça

  • Özlü T, Bülbül Y, Ozsu S. Community-acquired pneumonia based on the Turkish national data. Tuberk Toraks 2007; 55: 191-212.
  • Bates JH, Campbell GD, Barron AL, et al. Microbial etiology of acute pneumonia in hospitalized patients. Chest 1992; 101: 1005-12.
  • Fang GD, Fine M, Orloff J, et al. New and emerging etiologies for communityacquired pneumonia with implications for therapy; a prospective multicenter study of 359 cases. Medicine 1990; 69: 307-16.
  • Assicot M, Gendrel D, Carsin H, Raymond J, Guilbaud J, Bohuon C. High serum procalcitonin concentrations in patients with sepsis and infection. Lancet 1993; 341: 515-8.
  • Carrol ED, Thomson AP, Hart CA. Procalcitonin as a marker of sepsis. Int J Antimicrob Agents 2002; 20: 1-9.
  • Shehabi Y, Seppelt I. Pro/Con debate: Is procalcitonin useful for guiding antibiotic decision making in critically ill patients? Critical Care 2008; 12: 211.
  • Thompson D, Pepys MB, Wood SP. The physiological stucture of human C- reactive protein and its complex with phosphocholine. Structure 1999; 7: 169-77.
  • Jilma B, Blann A, Pernerstorfer T, et al. Regulation of adhesion molecules during human endotoxemia. No acute effects of aspirin. Am J Respir Crit Care Med 1999; 159: 857-63.
  • Zahorec R. Ratio of neutrophil to lymphocyte counts-Rapid and simple parameter of systemic inflammation and stress in critically ill. Bratisl Lek Listy 2001; 102: 5-14.
  • Şimşek S, Yurtseven N, Gerçekoğlu H, et al. Ventilator associated pneumonias in a cardiothoracic surgery centre postoperative intensive care unit. J Hosp Infect 2001; 47: 321-4.
  • Aybar M, Topeli A. Dahili yoğun bakım ünitesinde ventilatörle ilişkili pnömoni epidemiyolojisi. Yoğun Bakım Derg 2001; 1: 41- 6.
  • Çevik MA, Yılmaz GR, Erdinç FŞ, et al. Nöroloji Yoğun Bakım Ünitesinde mortalite ile ilişkili faktörler ve nozokomiyal enfeksiyonla mortalitenin ilişkisi. Yoğun Bakım Derg 2001; 1: 47-55.
  • Cazzola M, Centanni S, Blasi F. Have guidelines for the management of community-acquired pneumonia influenced outcomes? Respir Med 2003; 97: 205-11.
  • Sever F, Kömüs N, Esen N, Gündüz AT, Öktem MA, Çımrın AH. Türkiye’de toplum kökenli pnömoni etyoloji ve epidemiyolojisi. Turk Toraks Derg 2013; 14: 5-10.
  • Bircan A, Kaya Ö, Gökırmak M, Öztürk Ö, Sahin Ü, Akkaya A. Toplum kökenli pnömonilerin ağırlığının değerlendirilmesinde C-reaktif protein, lökosit sayısı ve eritrosit sedimentasyon hızının yeri. Tuberk Toraks 2006; 54: 22-9.
  • Fukuyama H, Ishida, Tachibana H, et al. Validation of scoring systems for predicting severe community-acquired pneumonia. Intern Med 2011; 50: 1917-22.
  • Yandiola PPE, Capelastegui A, Quintana J, et al. prospective comparison of severity scores for predicting clinically relevant outcomes for patients hospitalized with community-acquired pneumonia. Chest 2009; 135: 1572-9.
  • Murphy TF, Parameswaran GI. Moraxella catarrhalis, a human respiratory tract pathogen. Clin Infect Dis 2009; 49: 124-31.
  • Bircan A, Sutcu R, Gokırmak M. Total antioxidant capacity and C-reactive protein levels in patients with community-acquired pneumonia. Turk J Med Sci 2008; 38: 537-44.
  • Doruk S, Bulaç S, Sevinç C, Bodur HA, Yilmaz A, Erkorkmaz U. Severity scores and factors related with mortality in cases with community-acquired pneumonia patients in intensive care unit. Tuberk Toraks 2009; 57: 393-400.
  • Aujesky D, Auble TE, Yealy DM, et al. Prospective comparison of three validated prediction rules for prognosis in community-acquired pneumonia. Am J Med 2005; 118: 384-92.
  • Man SY, Lee N, Ip M, et al. Prospective comparison of three predictive rules for assessing severity of community acquired pneumonia in Hong Kong. Thorax 2007; 62: 348-53.
  • Shah BA, Ahmed W, Dhobi GN, Shah NN, Khursheed SQ, Haq I. Validity of pneumonia severity index and CURB-65 severity scoring systems in community acquired pneumonia in an Indian setting. Indian J Chest Dis Allied Sci 2010; 52: 9-17.
  • Monneret G, Labaune JM, Isaac C, Bienvenu F, Putet G, Bienvenu J. Procalcitonin and C-reactive protein levels in neonatal infections. Acta Paediatr 1997; 86: 209-12.
Toplam 24 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Sağlık Kurumları Yönetimi
Bölüm Research Articles
Yazarlar

Ahmet Beyaz Bu kişi benim 0000-0002-6927-5059

Nurhan Atilla 0000-0003-4127-4924

Hüseyin Arpağ 0000-0002-0942-6011

Fulsen Bozkuş 0000-0002-6498-4390

Hasan Kahraman 0000-0002-6196-1521

Fatih Uğuz Bu kişi benim 0000-0002-5125-0363

Yayımlanma Tarihi 22 Ocak 2021
Yayımlandığı Sayı Yıl 2021 Cilt: 3 Sayı: 1

Kaynak Göster

AMA Beyaz A, Atilla N, Arpağ H, Bozkuş F, Kahraman H, Uğuz F. The effect of C-reactive protein, procalcytonine, nuetrophil/lymphosite levels on mortality and duration of hospital stay in pneumonia. Anatolian Curr Med J / ACMJ / acmj. Ocak 2021;3(1):15-19. doi:10.38053/acmj.801894

Üniversitelerarası Kurul (ÜAK) Eşdeğerliği: Ulakbim TR Dizin'de olan dergilerde yayımlanan makale [10 PUAN] ve 1a, b, c hariç uluslararası indekslerde (1d) olan dergilerde yayımlanan makale [5 PUAN]

-  Dahil olduğumuz İndeksler (Dizinler) ve Platformlar sayfanın en altındadır.

Not: Dergimiz WOS indeksli değildir ve bu nedenle Q olarak sınıflandırılmamaktadır.

Yüksek Öğretim Kurumu (YÖK) kriterlerine göre yağmacı/şüpheli dergiler hakkındaki kararları ile yazar aydınlatma metni ve dergi ücretlendirme politikasını tarayıcınızdan indirebilirsiniz. https://dergipark.org.tr/tr/journal/3449/page/10809/update 

Dergi Dizin ve Platformları

TR Dizin ULAKBİM, Google Scholar, Crossref, Worldcat (OCLC), DRJI, EuroPub, OpenAIRE, Turkiye Citation Index, Turk Medline, ROAD, ICI World of Journal's, Index Copernicus, ASOS Index, General Impact Factor, Scilit.