The frequency of vitamin D deficiency in Ordu and its relationship with chronic diseases

Yıl 2022, Cilt: 4 Sayı: 1, 8 - 12, 24.01.2022

Harun Düğeroğlu , Yasemin Kaya

https://doi.org/10.38053/acmj.1002370

Öz

Aim: The aim of this study was to evaluate the frequency of vitamin D deficiency in adult patients admitted to our hospital in Ordu and the relationship between this deficiency and chronic diseases.
Material and Method: In our study, the vitamin D levels of 1432 patients aged 18 yeras and over who applied to the Internal Medicine outpatient clinic between 01.01.2019-31.12.2019 were retrospectively evaluated. Age, gender, chronic diseases were evaluated and vitamin D levels of the patients were measured. Patients with serum vitamin D level of <20 ng/ml are in the vitamin D deficiency group; Patients between 21-30 ng/ml are in the vitamin D insufficiency group; Patients >30 ng/ml were included in the normal vitamin D group.
Results: The study consisted of 1092 females (76.4%) and 340 males (23.6%). We found vitamin D deficiency and insufficiency in approximately 88.3% of the patients. In addition, serum vitamin D levels of female patients included in the study were found to be significantly lower than male patients (p=0.007). There were statistically significant differences between the groups in the number of patients included in the study who had a chronic disease and in the evaluation of their vitamin D levels (insufficient, deficient, normal)(p=0.021, p=0.012, p=0.047, p=0.043, p=0.032, respectively).
Conclusion: With this study, a very high rate of vitamin D deficiency and insufficiency, such as 88.3%, was found in Ordu. In addition, there was a significant relationship between vitamin D deficiency and chronic diseases in our study.

Anahtar Kelimeler

Vitamin D deficiency, 25-hydroxy vitamin D, frequency, chronic diseases, mortality.

Proje Numarası

yok

Kaynakça

• IOM (Institute of Medicine). Dietary reference intakes for calcium and vitamin D. Washington, DC: The National Academies Press; 2011.
• Meer IM, Middelkoop BJC, Boeke AJP, et al. Prevalence of vitamin D deficiency among Turkish, Moroccan, Indian and sub-Sahara African populations in Europe and their countries of origin: an overview. Osteoporos Int 2011; 22: 1009-21.
• Lips P. Vitamin D status and nutrition in Europe and Asia. J Steroid Biochem Molecul Biol 2007; 103: 620-5.
• WHOQOL Group. The Development of the World Health Organisation quality of life assessment: International perspectives. Heidelberg: Springer Veriag 1994; 3: 41-57.
• Champe PC, Harvey RA, Ferrier DR. Biyokimya. Çeviri Editörü: Ulukaya E. Lippincott’s Illustrated Reviews Serisinden. 3. Baskı. Nobel Tıp Kitapevleri. 2007.
• Schoor MN, Lips P. Worldwide vitamin D status. Best Pract Res Clin Endocrinol Metab 2011; 25: 671-80.
• Hekimsoy Z, Dinç G, Kafesçiler S, et al. Vitamin D status among adults in the Aegean region of Turkey. BMC Public Health 2010; 10: 782-8.
• Cannell JJ, Vieth R, Umhau JC, et al. Epidemic influenza and vitamin D. Epidemiol Infect 2006; 134: 1129-40.
• Schottker B, Haug U, Schomburg L, et al. Strong associations of 25-hydroxyvitamin D concentrations with all-cause, cardiovascular, cancer, and respiratory disease mortality in a large cohort study. Am J Clin Nutr 2013; 97: 782-93.
• Holick MF. Vitamin D: A millenium perspective. J Cell Biochem 2003; 88: 296-07.
• Holick MF, Chen TC. Vitamin D deficiency: a worldwide problem with health consequences. Am J Clin Nutr 2008; 87: 1080-6.
• Yap KS, Northcott M, Hoi AB, Morand EF, Nikpour M. Association of low vitamin D with high disease activity in an Australian systemic lupus erythematosus cohort. Lupus Sci Med 2015; 2: 64.
• Lee IM, Shiroma EJ, Lobelo F, Puska P, Blair SN, Katzmarzyk PT. Effect of physical inactivity on major non-communicable diseases worldwide: an analysis of burden of disease and life expectancy. Lancet 2012; 380: 219-29.
• Christodoulou S, Goula T, Ververidis A, Drosos G. Vitamin D and bone disease. Biomed Res Int 2013; 1: 1-6.
• Kumar GT, Chugh R, Eggersdorfer M. Poor vitamin D status in healthy population in India: a review of current evidence. Int J Vitam Nutr Res 2015; 85: 1-7.
• Atalay SG, Atalay R, Alkan BM, et al. Vitamin D deficiency in adults with musculoskeletal pain. Turk J Osteoporos 2015; 21: 101-4.
• Erol AM, Çelik C, Hacıoğlu K, et al. The relationship between vitamin D level and lipid profile in patients admitted to the Physical Medicine and Rehabilitation outpatient clinic. Ege Med J 2015; 54: 173-6.
• Açıkgöz A, Günay T, Uçku R. Vitamin D requirements and supplementation during pregnancy. TAF Prevent Med Bull 2013; 12: 597-608.
• Uçar F, Taşlıpınar MY, Soydaş AÖ, Özcan N. 25-OH Vitamin D levels in patients admitted to Ankara Etlik Training and Research Hospital. Eur J Basic Med Sci 2012; 2: 12-5.
• Öğüş E, Sürer H, Kılınç AŞ, et al. Evaluation of Vitamin D levels by months, gender and age. Ankara Med J 2015; 15: 1-5.
• Roomi MA, Farooq A, Ullah E, Lone KP. Hypovitaminosis D and its association with lifestyle factors. Pak J Med Sci 2015; 31: 1236-40.
• Pearce SHS, Cheetham TD. Diagnosis and management of vitamin D deficiency. BMJ 2010; 340: 5664.
• Chowdhury R, Kunutsor S, Vitezova A, et al. Vitamin D and risk of cause specific death: systematic review and meta-analysis of observational cohort and randomised intervention studies. BMJ 2014; 348: 1903.