Diş Hekimliğinde Oromaksillofasiyal Bölgeden Alınabilen Mezenkimal Kök Hücreler

Yıl 2022, Cilt: 11 Sayı: 2, 184 - 192, 18.05.2022

Sefer Mahmutoğlu , Ayşegül Mendi , Derviş Yılmaz

https://doi.org/10.54617/adoklinikbilimler.996609

Öz

Oromaksillofasiyal bölge mezenkimal kök hücreler için değerli bir kaynak olup, bu bölgede çekilmiş diş soketleri, çekilmiş dişler, yapışık dişeti dokusu, mandibular ve maksillar kemik iliğinden kolaylıkla mezenkimal kök hücre elde edilebilen kemik, kan damarları diş ve sinirlerden oluşan bir kombine kaynaktır. Kemik iliği kaynaklı mezenkimal kök hücreler, oromaksillofasiyal doku kaynaklı mezenkimal kök hücreler ile benzer özellikte olup alveolar kemik ve sinirlerin rejenerasyonu ,pulpal hasarların önlenmesi ve hasar görmüş dentoalveolar dokuların rejenerasyonu icin biyolojik bir cevap oluşturmaktadır. Ayrıca dişeti kaynaklı mezenkimal kök hücreler immün düzenleyici özellikleri ile klinik uygulamalarda dikkat çekmektedir. Oromaksillofasiyal doku kaynaklı mezenkimal kök hücreler gelecekte maksillofasiyal defektlerin tedavisi açısından büyük ümitler vaad etmektedir. Bu derlemede maksilofasiyal doku kaynaklı mezenkimal kök hücrelerin biyolojik ve fonksiyonel özellikleri ile vaad ettiği gelecek potansiyeli tartışılmıştır.

Anahtar Kelimeler

mezenkimal kök hücre, oromaksillofasiyal defektler, diş kaynaklı mezenkimal kök hücreler, alveolar kemik rejenerasyonu, oromaksillofasiyal defekt onarımı

Kaynakça

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