MEDICATION ADHERENCE IN SCHIZOPHRENIA AND ROLE OF PSYCHIATRIC NURSE
Yıl 2018,
Cilt: 7 Sayı: 1, 61 - 72, 29.06.2018
Esra Uslu
,
Kadriye Buldukoğlu
Kaynakça
- Refeans 1: Ascher-Svanum, H., Faries, DE., Zhu, B., Ernst, FR., Swartz, MS., Swanson, JW. 2006 Medication adherence and long-term functional outcomes in the treatment of schizophrenia in usual care. J Clin Psychiatry;67:453–460.
- Balıkcı, A., Erdem, M., Zincir, S., Bolu, A., Zincir, SB., Ercan, Uzun, O. 2013. Adherence with outpatient appointments and medication: a two-year prospective study of patients with schizophrenia, Klinik Psikofarmakol Bülten;23(1):57-64.
- Boardman, G., McCann, T., Kerr, D. 2014. A peer support programme for enhancing adherence to oral antipsychotic medication in consumers with schizophrenia, J Adv Nurs;70(10):2293–2302.
- Bright, CE. 2017. Measuring Medication Adherence in Patients With Schizophrenia: An Integrative Review. Arch Psychiatr Nurs;31(1):99-110
- Coodin, S., Staley, D., Cortens, B., Desrochers, R., McLandress, S. 2004. Patient factors associated with missed appointments in persons with schizophrenia. Can J Psychiatry;49:145–148.
- Çakır, F., İlnem, C., Yener, F. 2010. Kronik psikotik hastalarda taburculuk sonrası takip ve tedaviye uyum. Düşünen Adam Psikiyatri ve Nörolojik Bilimler Dergisi;23:50-59.
- Çetinkaya, DZ. 2003. Şizofreni tanılı bireylere ve ailelerine topluma yeniden katılım programı uygulaması ve izleme çalışması (Doktora Tezi-2003). İstanbul, İstanbul Üniversitesi.
- DiBonaventura, M., Gabriel, S., Dupclay, L., Gupta, S., Kim, E. A patient perspective of the impact of medication side effects on adherence: results of a crosssectional nationwide survey of patients with schizophrenia. BMC Psychiatry http://www.biomedcentral.com/1471-244X/12/20 (Ulaşım Tarihi:13 Temmuz 2017).
- Dikeç, G., Kutlu, Y. 2014. Bir grup şizofreni hastasında tedaviye uyum ve etkileyen etmenlerin belirlenmesi. Psikiyatri Hemşireliği Dergisi;5(3):143-148.
- Dolder, CR., Lacro, JP., Jeste, DV. 2003. Adherence to antipsychotic and nonpsychiatric medications in middle-aged and older patients with psychotic disorders. Psychosom Med;65:156–162.
- Emsley, R., Alptekin, K., Azorin, JM., Cañas, F., Dubois, V., Gorwood P., Haddad, PM., Naber, D., Olivares, JM., Georgios
Papageorgiou, JM., Roca, M., Thomas, P., Hargarter, L. 2015. Nurses’ perceptions of medication adherence in schizophrenia: results of the ADHES cross-sectional questionnaire survey. Ther Adv Psychopharmacol;5 8(6): 339-350.
- Eticha, T., Teklu, A., Ali, D., Solomon, G., Alemayehu, A. 2015. Factors associated with medication adherence among patients with schizophrenia in Mekelle, Northern Ethiopia;PLoS One, doi: 10.1371/journal.pone.0120560
- Gilmer, TP., Dolder,CR., Lacro, JP., Folsom, DP., Lindamer, L., Garcia, P., Jesta DP. 2004. Adherence to treatment with antipsychotic medication and health care costs among Medicaid beneficiaries with schizophrenia. Am J Psychiatry;161(4):692-699.
- Goff, DC., Hill, M., Freudenreich, O. 2010. Strategies for improving treatment adherence in schizophrenia and schizoaffective disorder. J Clin Psychiatry;71(2):20–26.
- Hegedus, A., Kozel, B. 2014. Does adherence therapy improve medication, adherence among patients with schizophrenia? A systematic review. Int J Ment Health Nurs;23:490–497
- Jaeger, S., Flammer, E., Steinert, T. 2014. Control beliefs, therapeutic relationship, and adherence in schizophrenia outpatients: a cross-sectional study. Am J Health Behav;38(6):914-923.
- Jeste, SD., Patterson, TL., Palmer, BW., Dolderb, CR., Goldmanb, S., Jeste, DV. 2003. Cognitive predictors of medication adherence among middle-aged and older outpatients with schizophrenia. Schizophr Res;63:49–58.
- Kelleci, M., Ata, EE. 2011. Psikiyatri kliniğinde yatan hastaların ilaç uyumları ve sosyal destekle ilişkisi. Psikiyatri Hemşireliği Dergisi;2(3):105-110.
- Kikkert, MJ., Schene, AH., Koeter, MW., Robson, D., Born, A., Helm, H., Nose, M., Goss C, Thornicroft, G., Gray RJ. 2006. Medication adherence in schizophrenia: exploring patients’, carers’ and professionals’ views. Schizophr Bull;32:786–794.
- Knapp, M., Mangalore, R., Simon, J. 2004.The Global Costs of Schizophrenia. Schizophr Bull;30(2): 279-93.
- Koç, A. 2006. Kronik psikoz hastalarında tedavi uyumunun ve tedavi uyumu ile ilişkili etkenlerin değerlendirilmesi (Uzmanlık Tezi-2006). Ankara, Gazi Üniversitesi.
- Lacro, JP., Dunn, LB., Dolder, CR., Leckband, SG., Jeste, DV. 2002. Prevalence of and risk factors for medication nonadherence in patients with schizophrenia: a comprehen-sive review of recent literature. J Clin Psychiatry;63:892–909.
- Lam, JW., Lui, SS., Wang, Y., Chan, RC., Cheung, EF. 2013. Prospective memory predicts medication management ability and correlates with non-adherence to medications in individuals with clinically stable schizophrenia. Schizophr Res;147(2-3):293-300
- Lecomte, T., Spidel, A., Leclerc, C., MacEwan, GW., Greaves, C., Bentall, RP. 2008. Predictors and profiles of treatment non-adherence and engagement in services problems in early psychosis. Schizophr Res;102:295–302
- Lindström, E., Bingefors, K. 2000. Patient compliance with drug therapy in schizophrenia economic and clinical ıssues. Pharmacoeconomics;18(2):105-124.
- Masand, PS., Narasimhan, M. 2006. Improving adherence to antipsychotic pharmacotherapy. Curr Clin Pharmacol;1:47–56.
- McIntosh, AM., Conlon, L., Lawrie, SM., Stanfield, AC. 2006. Compliance therapy for schizophrenia review. Cochrane Database Syst Rev;(3):1-16.
- Mitchell, AJ., Selmes, T. 2007. Why don’t patients attend their appointments? Maintaining engagement with psychiatric services. Adv Psychiatr Treat;13:423–434.
- Moyet, JCM. 2010. Handbook of Nursing Diagnosis. pp. 466-468 (Çeviri Ed. F. Erdemir). İstanbul; Nobel Matbaacılık 2010;
- Na, E., Yim, SJ., Lee, JN., Kim, JM., Hong, K., Hong, MH., Han H. 2015. Relationships among medication adherence, insight, and neurocognition in chronic schizophrenia. Psychiatry Clin Neurosci;69(5):298-304
- Nosé, M., Barbui, C., Tansella, M. 2003. How often do patients with psychosis fail to adhere to treatment programmes? A systematic review. Psychol Med;33:1149–1160
- Novick, D., Haro, JM., Suarez, D., Perez, V., Dittmann, RW., Haddad, PM. 2010. Predictors and clinical consequences of non-adherence with antipsychotic medication in the outpatient treatment of schizophrenia.Psychiatry Res;176:109–113
Olfson, M., Mechanic, D., Hansell, S., Boyer, CA., Walkup, J., Weiden, PJ. 2000. Predicting medication noncompliance after hospital discharge among patients with schizophrenia. Psychiatr Serv;51:216–222
Piette, JD., Heisler, M., Ganoczy, D., McCarthy, JF., Valenstein, M. 2007. Differential medication adherence among patients with schizophrenia and comorbid diabetes and hypertension. Psychiatr Serv;58:207–212.
Ruscher, SM., Wit, R., Mazmanian, D. 1997. Psychiatric patients’ attitudes about medication and factors affecting noncompliance. Psychiatr Serv;48:82–85.
Sun, SX., Liu, GG., Christensen, DB., Fu, AZ. 2007. Review and analysis of hospitalization costs associated with antipsychotic nonadherence in the treatment of schizophrenia in the United States. Curr Med Res Opin;23:2305–2312.
Tunis, SL., Faries, DE., Stensland, MD. 2007. An examination of factors affecting persistence with initial antipsychotic treatment in patients with schizophrenia.Curr Med Res Opin;23:97–104.
Uslu, E. 2017. Telefonla problem çözme müdahalesinin şizofreni tanılı bireylerin ilaç tedavisine uyumuna etkisi (Doktora Tezi-2017). Antalya, Akdeniz Üniversitesi.
Ünal, S., Çakıl, G., Elya, Z. 2006. Taburculuk sonrası tedaviye gelmeyen psikotik hastaların özellikleri. Anadolu Psikiyatri Derg;7:69-75.
Velligan, DI., Satajovic, M., Valenstein, M., Riley, W., Safren, S., Lewis-Fernandez, R., Weiden, P., Ogedegbe, G., Jamison, J. 2010. Methodological challenges in psychiatric treatment adherence research. Clin Schizophr Relat Psychoses;4(1):74-91.
Velligan, DI., Diamond, PM., Mintz, J., Maples, N., Li, X., Zeber, J., Ereshefsky, L., Lam, YW., Castillo, D., Miller, AL. 2008. The use of individually tailored environmental supports to improve medication adherence and outcomes in schizophrenia. Schizophr Bull;34:483–493.
Velligan, DI., Dicocco, M., Castillo, D., Maples, NL., Lam, YW., Ereshefsky, L., Miller AL. 2003. Obstacles in assessing adherence to oral antipsychotic medications. Schizophr Res;15(1):330.
Velligan, DI., Lam, YWF., Glahn, DC., Barrett, JA., Maples, NJ., Ereshefsky, L., Miller AL. 2006. Defining and assessing adherence to oral antipsychotics: a review of the literature.Schizophr Bull;32(4):724-742.
Velligan, DI., Sajatovic, M., Hatch, A., Kramata, P., Docherty, JP. 2017. Why do psychiatric patients stop antipsychotic medication? A systematic review of reasons for nonadherence to medication in patients with serious mental illness. Patient Prefer Adherence;3(11):449-468
Velligan, DI., Wang, M., Diamond, P., Glahn, DC., Castillo, D., Bendle, S. Lam YWF, Ereshefsky L, Miller AL. 2007. Relationships among subjective and objective measures of adherence to oral antipsychotic medications. Psychiatr Serv;58:1187–1192.
Velligan, DI., Weiden, PJ., Sajatovic, M., Scott, J., Carpenter, D., Ross, R., Docherty, JP. 2009. The expert consensus guideline series: adherence problems in patients with serious and persistent mental illness.J Clin Psychiatry;70(4):1–46.
Velligan, DI., Weiden, PJ., Sajatovic, M., Scott, J., Carpenter, D., Ross, R., Docherty, JP. 2010. Assessment of adherence problems in patients with serious and persistent mental illness: recommendations from the expert consensus guidelines.J Psychiatr Pract;16:34-45.
Weiden, P., Rapkin, B., Zygmunt, A., Mott, T., Goldman, D., Frances, A. 1995. Postdischarge medication compliance of inpatients converted from an oral to a depot neuroleptic regimen. Psychiatr Serv;46:1049–1054
Weiden, PJ., Kozma, C., Grogg, A., Locklear, J. 2004. Partial compliance and risk of rehospitalization among California Medicaid patients with schizophrenia. Psychiatr Serv;55(8):886-89.
World Health Organization-WHO. Schizophrenia. (Ulaşım Tarihi: 13 Temmuz 2017).http://www.who.int/mediacentre/factsheets/fs397/en/
Yang, J., Ko, YH., Paik, JW., Lee, MS., Han, C., Joe, SH., Jung, IK., Jung, HG., Kim, SH. 2012. Symptom severity and attitudes toward medication: Impacts on adherence in outpatients with schizophrenia. Schizophr Res;134:226–23
Zhoua, Y., Rosenheckb, R., Mohamedb, S., Ninga, Y., Hea, H. 2017. Factors associated with complete discontinuation of medication among patients with schizophrenia in the year after hospital discharge.Psychiatry Res;250:129–13
ŞİZOFRENİDE İLAÇ TEDAVİSİNE UYUM VE PSİKİYATRİ HEMŞİRESİNİN ROLÜ
Yıl 2018,
Cilt: 7 Sayı: 1, 61 - 72, 29.06.2018
Esra Uslu
,
Kadriye Buldukoğlu
Öz
Özet
Şizofreni, dünyada 21 milyondan fazla kişiyi etkileyen ve hastalık yüküne sebep olan bir hastalıktır. Psikofarmakalojik girişimlerin kanıtlanan yararlarına karşın bu hastaların yaklaşık yarısının ilaç tedavisine uyum sağlamadığı bilinmektedir. Oysa şizofreni hastalarının ilaç tedavisine uyum problemleri; hastaneye yeniden yatış oranlarında ve sağlık giderlerinde artışa, hastalık semptomlarında alevlenmeye, nükse, işlevsellikte bozulmaya ve intihara kadar varan birçok olumsuz sonuca neden olmaktadır. Bu sonuçlar göz önünde bulundurulduğunda şizofreni hastalarının ilaç tedavisine uyumunu artırmanın bir zorunluluk olduğu ortaya çıkmaktadır. Bu problemin yönetiminde öncelikli olarak şizofreni hastalarında ilaç tedavisine uyumu güçleştiren faktörler belirlenmelidir. İlaç tedavisine uyumun sağlanmasının psikiyatri hemşirelerinin öncelikli hedefleri arasında yer aldığı dikkate alındığında, hemşireler bu problemin çözümünde anahtar rol oynamaktadırlar. Bu derleme şizofreni hastalarında ilaç tedavisine uyumunu güçleştiren faktörleri ve ilaç tedavisine uyum problemlerinin yönetiminde psikiyatri hemşiresinin rolünü literatür bilgisi doğrultusunda incelemek amacı ile yazılmıştır.
İngilizce Özet
Giriş
Materyal ve Yöntem
Bulgular
Tartışma
Sonuç
Referanslar
Kaynakça
- Refeans 1: Ascher-Svanum, H., Faries, DE., Zhu, B., Ernst, FR., Swartz, MS., Swanson, JW. 2006 Medication adherence and long-term functional outcomes in the treatment of schizophrenia in usual care. J Clin Psychiatry;67:453–460.
- Balıkcı, A., Erdem, M., Zincir, S., Bolu, A., Zincir, SB., Ercan, Uzun, O. 2013. Adherence with outpatient appointments and medication: a two-year prospective study of patients with schizophrenia, Klinik Psikofarmakol Bülten;23(1):57-64.
- Boardman, G., McCann, T., Kerr, D. 2014. A peer support programme for enhancing adherence to oral antipsychotic medication in consumers with schizophrenia, J Adv Nurs;70(10):2293–2302.
- Bright, CE. 2017. Measuring Medication Adherence in Patients With Schizophrenia: An Integrative Review. Arch Psychiatr Nurs;31(1):99-110
- Coodin, S., Staley, D., Cortens, B., Desrochers, R., McLandress, S. 2004. Patient factors associated with missed appointments in persons with schizophrenia. Can J Psychiatry;49:145–148.
- Çakır, F., İlnem, C., Yener, F. 2010. Kronik psikotik hastalarda taburculuk sonrası takip ve tedaviye uyum. Düşünen Adam Psikiyatri ve Nörolojik Bilimler Dergisi;23:50-59.
- Çetinkaya, DZ. 2003. Şizofreni tanılı bireylere ve ailelerine topluma yeniden katılım programı uygulaması ve izleme çalışması (Doktora Tezi-2003). İstanbul, İstanbul Üniversitesi.
- DiBonaventura, M., Gabriel, S., Dupclay, L., Gupta, S., Kim, E. A patient perspective of the impact of medication side effects on adherence: results of a crosssectional nationwide survey of patients with schizophrenia. BMC Psychiatry http://www.biomedcentral.com/1471-244X/12/20 (Ulaşım Tarihi:13 Temmuz 2017).
- Dikeç, G., Kutlu, Y. 2014. Bir grup şizofreni hastasında tedaviye uyum ve etkileyen etmenlerin belirlenmesi. Psikiyatri Hemşireliği Dergisi;5(3):143-148.
- Dolder, CR., Lacro, JP., Jeste, DV. 2003. Adherence to antipsychotic and nonpsychiatric medications in middle-aged and older patients with psychotic disorders. Psychosom Med;65:156–162.
- Emsley, R., Alptekin, K., Azorin, JM., Cañas, F., Dubois, V., Gorwood P., Haddad, PM., Naber, D., Olivares, JM., Georgios
Papageorgiou, JM., Roca, M., Thomas, P., Hargarter, L. 2015. Nurses’ perceptions of medication adherence in schizophrenia: results of the ADHES cross-sectional questionnaire survey. Ther Adv Psychopharmacol;5 8(6): 339-350.
- Eticha, T., Teklu, A., Ali, D., Solomon, G., Alemayehu, A. 2015. Factors associated with medication adherence among patients with schizophrenia in Mekelle, Northern Ethiopia;PLoS One, doi: 10.1371/journal.pone.0120560
- Gilmer, TP., Dolder,CR., Lacro, JP., Folsom, DP., Lindamer, L., Garcia, P., Jesta DP. 2004. Adherence to treatment with antipsychotic medication and health care costs among Medicaid beneficiaries with schizophrenia. Am J Psychiatry;161(4):692-699.
- Goff, DC., Hill, M., Freudenreich, O. 2010. Strategies for improving treatment adherence in schizophrenia and schizoaffective disorder. J Clin Psychiatry;71(2):20–26.
- Hegedus, A., Kozel, B. 2014. Does adherence therapy improve medication, adherence among patients with schizophrenia? A systematic review. Int J Ment Health Nurs;23:490–497
- Jaeger, S., Flammer, E., Steinert, T. 2014. Control beliefs, therapeutic relationship, and adherence in schizophrenia outpatients: a cross-sectional study. Am J Health Behav;38(6):914-923.
- Jeste, SD., Patterson, TL., Palmer, BW., Dolderb, CR., Goldmanb, S., Jeste, DV. 2003. Cognitive predictors of medication adherence among middle-aged and older outpatients with schizophrenia. Schizophr Res;63:49–58.
- Kelleci, M., Ata, EE. 2011. Psikiyatri kliniğinde yatan hastaların ilaç uyumları ve sosyal destekle ilişkisi. Psikiyatri Hemşireliği Dergisi;2(3):105-110.
- Kikkert, MJ., Schene, AH., Koeter, MW., Robson, D., Born, A., Helm, H., Nose, M., Goss C, Thornicroft, G., Gray RJ. 2006. Medication adherence in schizophrenia: exploring patients’, carers’ and professionals’ views. Schizophr Bull;32:786–794.
- Knapp, M., Mangalore, R., Simon, J. 2004.The Global Costs of Schizophrenia. Schizophr Bull;30(2): 279-93.
- Koç, A. 2006. Kronik psikoz hastalarında tedavi uyumunun ve tedavi uyumu ile ilişkili etkenlerin değerlendirilmesi (Uzmanlık Tezi-2006). Ankara, Gazi Üniversitesi.
- Lacro, JP., Dunn, LB., Dolder, CR., Leckband, SG., Jeste, DV. 2002. Prevalence of and risk factors for medication nonadherence in patients with schizophrenia: a comprehen-sive review of recent literature. J Clin Psychiatry;63:892–909.
- Lam, JW., Lui, SS., Wang, Y., Chan, RC., Cheung, EF. 2013. Prospective memory predicts medication management ability and correlates with non-adherence to medications in individuals with clinically stable schizophrenia. Schizophr Res;147(2-3):293-300
- Lecomte, T., Spidel, A., Leclerc, C., MacEwan, GW., Greaves, C., Bentall, RP. 2008. Predictors and profiles of treatment non-adherence and engagement in services problems in early psychosis. Schizophr Res;102:295–302
- Lindström, E., Bingefors, K. 2000. Patient compliance with drug therapy in schizophrenia economic and clinical ıssues. Pharmacoeconomics;18(2):105-124.
- Masand, PS., Narasimhan, M. 2006. Improving adherence to antipsychotic pharmacotherapy. Curr Clin Pharmacol;1:47–56.
- McIntosh, AM., Conlon, L., Lawrie, SM., Stanfield, AC. 2006. Compliance therapy for schizophrenia review. Cochrane Database Syst Rev;(3):1-16.
- Mitchell, AJ., Selmes, T. 2007. Why don’t patients attend their appointments? Maintaining engagement with psychiatric services. Adv Psychiatr Treat;13:423–434.
- Moyet, JCM. 2010. Handbook of Nursing Diagnosis. pp. 466-468 (Çeviri Ed. F. Erdemir). İstanbul; Nobel Matbaacılık 2010;
- Na, E., Yim, SJ., Lee, JN., Kim, JM., Hong, K., Hong, MH., Han H. 2015. Relationships among medication adherence, insight, and neurocognition in chronic schizophrenia. Psychiatry Clin Neurosci;69(5):298-304
- Nosé, M., Barbui, C., Tansella, M. 2003. How often do patients with psychosis fail to adhere to treatment programmes? A systematic review. Psychol Med;33:1149–1160
- Novick, D., Haro, JM., Suarez, D., Perez, V., Dittmann, RW., Haddad, PM. 2010. Predictors and clinical consequences of non-adherence with antipsychotic medication in the outpatient treatment of schizophrenia.Psychiatry Res;176:109–113
Olfson, M., Mechanic, D., Hansell, S., Boyer, CA., Walkup, J., Weiden, PJ. 2000. Predicting medication noncompliance after hospital discharge among patients with schizophrenia. Psychiatr Serv;51:216–222
Piette, JD., Heisler, M., Ganoczy, D., McCarthy, JF., Valenstein, M. 2007. Differential medication adherence among patients with schizophrenia and comorbid diabetes and hypertension. Psychiatr Serv;58:207–212.
Ruscher, SM., Wit, R., Mazmanian, D. 1997. Psychiatric patients’ attitudes about medication and factors affecting noncompliance. Psychiatr Serv;48:82–85.
Sun, SX., Liu, GG., Christensen, DB., Fu, AZ. 2007. Review and analysis of hospitalization costs associated with antipsychotic nonadherence in the treatment of schizophrenia in the United States. Curr Med Res Opin;23:2305–2312.
Tunis, SL., Faries, DE., Stensland, MD. 2007. An examination of factors affecting persistence with initial antipsychotic treatment in patients with schizophrenia.Curr Med Res Opin;23:97–104.
Uslu, E. 2017. Telefonla problem çözme müdahalesinin şizofreni tanılı bireylerin ilaç tedavisine uyumuna etkisi (Doktora Tezi-2017). Antalya, Akdeniz Üniversitesi.
Ünal, S., Çakıl, G., Elya, Z. 2006. Taburculuk sonrası tedaviye gelmeyen psikotik hastaların özellikleri. Anadolu Psikiyatri Derg;7:69-75.
Velligan, DI., Satajovic, M., Valenstein, M., Riley, W., Safren, S., Lewis-Fernandez, R., Weiden, P., Ogedegbe, G., Jamison, J. 2010. Methodological challenges in psychiatric treatment adherence research. Clin Schizophr Relat Psychoses;4(1):74-91.
Velligan, DI., Diamond, PM., Mintz, J., Maples, N., Li, X., Zeber, J., Ereshefsky, L., Lam, YW., Castillo, D., Miller, AL. 2008. The use of individually tailored environmental supports to improve medication adherence and outcomes in schizophrenia. Schizophr Bull;34:483–493.
Velligan, DI., Dicocco, M., Castillo, D., Maples, NL., Lam, YW., Ereshefsky, L., Miller AL. 2003. Obstacles in assessing adherence to oral antipsychotic medications. Schizophr Res;15(1):330.
Velligan, DI., Lam, YWF., Glahn, DC., Barrett, JA., Maples, NJ., Ereshefsky, L., Miller AL. 2006. Defining and assessing adherence to oral antipsychotics: a review of the literature.Schizophr Bull;32(4):724-742.
Velligan, DI., Sajatovic, M., Hatch, A., Kramata, P., Docherty, JP. 2017. Why do psychiatric patients stop antipsychotic medication? A systematic review of reasons for nonadherence to medication in patients with serious mental illness. Patient Prefer Adherence;3(11):449-468
Velligan, DI., Wang, M., Diamond, P., Glahn, DC., Castillo, D., Bendle, S. Lam YWF, Ereshefsky L, Miller AL. 2007. Relationships among subjective and objective measures of adherence to oral antipsychotic medications. Psychiatr Serv;58:1187–1192.
Velligan, DI., Weiden, PJ., Sajatovic, M., Scott, J., Carpenter, D., Ross, R., Docherty, JP. 2009. The expert consensus guideline series: adherence problems in patients with serious and persistent mental illness.J Clin Psychiatry;70(4):1–46.
Velligan, DI., Weiden, PJ., Sajatovic, M., Scott, J., Carpenter, D., Ross, R., Docherty, JP. 2010. Assessment of adherence problems in patients with serious and persistent mental illness: recommendations from the expert consensus guidelines.J Psychiatr Pract;16:34-45.
Weiden, P., Rapkin, B., Zygmunt, A., Mott, T., Goldman, D., Frances, A. 1995. Postdischarge medication compliance of inpatients converted from an oral to a depot neuroleptic regimen. Psychiatr Serv;46:1049–1054
Weiden, PJ., Kozma, C., Grogg, A., Locklear, J. 2004. Partial compliance and risk of rehospitalization among California Medicaid patients with schizophrenia. Psychiatr Serv;55(8):886-89.
World Health Organization-WHO. Schizophrenia. (Ulaşım Tarihi: 13 Temmuz 2017).http://www.who.int/mediacentre/factsheets/fs397/en/
Yang, J., Ko, YH., Paik, JW., Lee, MS., Han, C., Joe, SH., Jung, IK., Jung, HG., Kim, SH. 2012. Symptom severity and attitudes toward medication: Impacts on adherence in outpatients with schizophrenia. Schizophr Res;134:226–23
Zhoua, Y., Rosenheckb, R., Mohamedb, S., Ninga, Y., Hea, H. 2017. Factors associated with complete discontinuation of medication among patients with schizophrenia in the year after hospital discharge.Psychiatry Res;250:129–13