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Kas-İskelet Sistemi Rahatsızlıklarında Kullanılan Bitkisel Droglar

Yıl 2022, Cilt: 3 Sayı: 2, 31 - 50, 29.04.2022
https://doi.org/10.53445/batd.944819

Öz

Kas-iskelet sistemi rahatsızlıklarının önemli bir kısmı, teşhis ve tedavisi zor olan kronik hastalıklardan oluşmaktadır. İlaç tedavisinin yetersizliği, ağrı, fonksiyon kaybı, devamında işgücü kaybı ve yaşam kalitesinde düşme gibi sebeplerden dolayı hastalar tamamlayıcı tedavi yöntemlerine yönelmektedirler. Ülkemizde fizik tedavi, balneoterapi, akupunktur, proloterapi, mezoterapi, kayropraktik, kupa gibi birçok tamamlayıcı tedavi yöntemlerinin yanı sıra bitkilerle tedavi de sık kullanılan yöntemler arasında yer almaktadır. Bu çalışmada amaç; bitkilere ve bitkisel tedavilere ilginin ve bu alandaki gelişmelerin giderek artması nedeniyle, toplumda sık görülen kas-iskelet sistemi rahatsızlıklarında tedavi amaçlı kullanılan bitkiler hakkında daha kapsamlı bilgi sahibi olmaktır. Bu amaçla, en çok kullanılan bitkiler ve bu bitkilerin kas-iskelet sistemi hastalıklarının tedavisindeki yeri, çeşitli arama motorlarına farklı anahtar kelimeler girilerek yapılan taramaların yanı sıra, kütüphanelerde bulunan bilimsel kitap, dergi, monograf gibi kaynaklar da incelenerek, kas-iskelet sistemi rahatsızlıklarında kullanılan bitkiler tespit edilmiş, ilgili literatüre ulaşılarak bu çalışma için gerekli kaynaklar sağlanmıştır ve sunulmuştur. Bitkisel ürün seçiminde ürünün Sağlık Bakanlığı onaylı olması ve hekimin bilgisi dahilinde kullanılması hususuna mutlaka dikkat edilmelidir. Bitkisel ürünlerin kullanımının ve sağlık üzerine etkilerinin değerlendirilmesi için ileri düzeyde, daha uzun süreli, yüksek dozlarda, daha fazla katılımcı ile kontrollü, randomize ve çift körlü tasarlanmış klinik çalışmalar gerekmektedir.

Kaynakça

  • Adams, M., Berset, C., Kessler, M., Hamburger, M. (2009). Medicinal herbs for thetreatment of rheumatic disorders-a survey of European herbals from the 16th and 17th century. Journal of Ethnopharmacology, 121, 343–359.
  • Ağalar, H.G., Göğer, F., Demirci, B., Malyer, H., Kırımer N. (2020). Angelica slyvestris var. slyvestris L.: Essential oils and antioxidant activity evaluation. Eskişehir Technical Unıv. J. of Sci. and Tech. A- Appl. Sci. and Eng. 21(1), 39-48. DOI: 10.18038/estubtda.544889.
  • Akbay, P., Başaran, A.A., Undeger, U., Başaran, N. (2003). In vitro immunomodulatory activity of flavonoid glycosides from Urtica dioica L. Phytother Res.17(1), 34–37.
  • Aktaş Şenocak, E., Apaydın Yıldırım, B. (2017). Ratlarda parasetamol ile oluşturulan hepatotoksisite üzerine Taraxacum officinale etanol ekstraktının etkisi. Harran Univ. Vet. Fak. Derg, 6(1), 11-18.
  • Alp, H. (2020). Konya-Akyokuş yöresinde yetişen sarı kantaron (Hypericum perforatum) bitkisinin fitokimyasal analizi. Necmettin Erbakan Univ Sağlık Bilim Derg, 2 (2), 1-7.
  • Alp, H., Şen, M. (2020). Investigation of the Components of Lavender Plant Grown in Konya-Turkey Region. J Tradit Complem Med, 3 (2), 166-70.
  • Altay, B., Gönener, H.D., İslam, K., Göv, P. (2010). Fizik tedavi alan hastaların yaşam kalitesinin değerlendirilmesi. Gaziantep Tıp Derg,16(2), 29-35.
  • Alvarez-Nemegyei, J.,Bautista-Botello, A., Dávila-Velázquez, J. (2009). Association of complementary or alternative medicine use with quality of life, functional status or cumulated damage in chronic rheumatic diseases, Clin Rheumatol, 28, 547–551.
  • Avan, M. (2021). Türkiye’de ve dünyada görülen önemli tıbbi ve aromatik bitkiler, özellikleri ve hastalıkları üzerine araştırmalar. Uluslararası Doğu Anadolu Fen Mühend Tasar Derg,3(1), 129-156.
  • Axmann, S., Hummel, K., Nöbauer, K., Razzazi-Fazeli, E., Zitterl-Eglseer, K. (2019). Pharmacokinetics of harpagoside in horses after intragastric administration of a Devil’s claw (Harpagophytum procumbens) extract.J vet Pharmacol Therap.42:37–44.
  • Ayan, A.K., Çalışkan, Ö., Çırak, C.T. (2006). Isırgan otu (Urtica spp.)’nun ekonomik önemi ve tarımı. OMÜ Zir Fak Derg, 21(3), 357-363.
  • Azman, N.A.M., Skowyra, M., Muhammed, K., Gallego, M.G., Almajano, M.P. (2017). Evaluation of the antioxidant activity of Betula pendula leaves extract and its effects on model foods. J Pharm Biol, 55 (1), 912-919.
  • Bahmani M, Rafieian-Kopaei M, Jeloudari M, Eftekhari Z, Delfan B, Zargaran A, Forouzan S. (2014). A review of the health effects and uses of drugs of plant licorice (Glycyrrhiza glabra L.) in Iran. Asian Pac J Trop Dis, 4(2), 847-849.
  • Batiha, G.E.S., Beshbishy, A.M., El-Mleeh, A., Abdel-Daim, M.M., Devkota, H.P. (2020). Traditional uses, bioactive chemical constituents, and pharmacological and toxicological activities of Glycyrrhiza glabra L. (Fabaceae). Biomolecules,10, 352.
  • Baytop, T. (1999). Türkiye’de bitkiler ile tedavi. İstanbul:Nobel Tıp Kitabevleri. “2. Baskı”.
  • Bhat, Z.A., Kumar, D., Shah, M.Y. (2011). Angelica archangelica Linn. is an angel on earth for the treatment of diseases. Int J Nutr, 1(1), 36-50.
  • Bilenler, T., Gökbulut, İ. (2019). Hastane patojenlerinin ticari uçucu yağlara karşı hassasiyetlerinin belirlenmesi. GÜFBED/GUSTIJ. 9 (3), 716-723.
  • Boulekbache-Makhlouf, L., Slimanı, S., Madai, K. (2013). Total phenolic content, antioxidant and antibacterial activities of fruits of Eucalyptus globulus cultivated in Algeria. Ind Crops Prod, 41, 85–89.
  • Brussell, D.E. (2004). Medicinal plants of Mt. Pelion, Greece. Economic Botany, 58 (Supplement), 174–202.
  • Calapai, G., Minciullo, P.L., Miroddi, M., Chinou, I., Gangemi, S., Schmidt, R.J. (2016). Contact dermatitis as an adverse reaction to some topically used European herbal medicinal products–part 3:Mentha × piperita – Solanum dulcamara. Contact Dermatitis,74(3), 131–144.
  • Chen, J., Tang, C., Zhang, R., Ye, S., Zhao, Z., Huang, Y., Yang, D. (2020). Metabolomics analysis to evaluate the antibacterial activity of the essential oil from the leaves of Cinnamomum camphora (Linn.) Presl. J Ethnopharmacol, 253, 112652.
  • Craciunescu, O., Constantin, D., Gaspar, A., Toma, L., Utoiu, E., Moldovan, L. (2012). Evaluation of antioxidant and cytoprotective activities of Arnica montana L. and Artemisia absinthium L. ethanolic extracts. Chem Cent J, 6,97.
  • Cukanovic, J., Tesevic, V., Jadranin, M., Jubojevic, M., Mladenovic, E., Kostic, S. (2020). Horse chestnut (Aesculus hippocastanumL.) seed fatty acids, flavonoids and heavy metals plasticity to different urban environments. Bio Syst Eco, 89, 103980.
  • Çelik, S.A., Ayran, İ. (2020). Antioksidan kaynağı olarak bazı tıbbi ve aromatik bitkiler. Türk Bilimsel Derlemeler Derg, 13(2), 115-125.
  • Çırak, C., Kurt, D.(2014). Önemli tıbbi bitkiler olarak Hypericum türleri. Anadolu, 24 (1), 42 – 58.
  • Çolak, S., Çömlekçioğlu, N., Aygan, A. (2020). Urtica dioica L.özütlerinin antioksidan ve antimikrobiyal aktivitelerinin incelenmesi. Eurasian J Bio Chem Sci.3(1), 206-212.
  • De Athayde, AE., de Araujo, CES., Sandjo, LP., Biavatti, MW. (2021). Metabolomic analysis among ten traditional "Arnica" (Asteraceae) from Brazil. J Ethnopharmacol. 265, 113149.
  • De Macedo, L.M., Santos, É.M. dos, Militão, L., Tundisi, L.L., Ataide, J.A., Souto, E.B., Mazzola, P.G. (2020). Rosemary (Rosmarinus officinalis L., syn Salvia rosmarinus spenn.) and Its Topical Applications: A Review. Plants, 9(5), 651. doi:10.3390/plants9050651.
  • De Oliveira, J.R., Camargo, S.E.A., de Oliveira, L.D. (2019). Rosmarinus officinalis L. (rosemary) as therapeutic and prophylactic agent. J Bio Sci, 26,5.
  • Di Sottoa, A., Vecchiatoa, M., Abetea, L., Toniolob, C., Giustic, A.M., Manninad, L., Locatellie, M., Nicolettib, M., Di Giacomo, S. (2018).Capsicum Annuum L. var. Cornetto di Pontecorvo PDO: Polyphenolic Profile and in vitro Biological Activities. J Func Foods, 40, 679–691.
  • Dobrowolska, I., Andrade, G.M., Clapham, D., Egertsdotter, U. (2017). Histological analysis reveals the formation of shoots rather than embryos in regenerating cultures of Eucalyptus globulus. Plant Cell Tiss Organ Cult, 128, 319–326.
  • Düzgüner, V., Erbil, V. (2020). Ardahan yöresinde yetişen kılıç otu bitkisinin (Hypericum perforatum) antimikrobiyal ve antioksidan etkilerinin araştırılması. Türk Tarım ve Doğa Bilim Derg, 7(1), 27–31.
  • El Beyrouthy, M., Arnold, N., Delelis-Dusollier, A., Dupont, F. (2008). Plants used as remedies antirheumatic and antineuralgic in the traditional medicine of Lebanon. J Ethnopharmacol, 120, 315– 334.
  • El Omari, N., Ezzahrae Guaouguaou, F., El Menyiy, N., Benali, T., Aanniz, T., Chamkhi, I., Bouyahya, A. (2021). Phytochemical and biological activities of Pinus halepensis Mill., and their ethnomedicinal use. J Ethnopharmacol. 268:113661.
  • Ezberci, F., Ünal, E. (2018). Hemoroidal hastalığın tedavisinde Aesculus Hippocastanum (Aescin, at kestanesi) kullanımı. Turk J Colorectal Dis, 28, 54-57.
  • Galindo-Jaıme, L., González-Espinosa, M., Quintana-Ascencio, P., García-Barrios, L. (2002). Tree composition and structure in disturbed stands with varying dominance byPinus spp. in the highlands of Chiapas, México. Plant Ecology, 162, 259–272.
  • Güneş, DŞ. (2011). Romatizmal hastalıkların tedavisinde sıklıkla kullanılan bitkiler ve bitkisel ürünler. Erciyes Üniversitesi eczacılık fakültesi farmakognozi ABD bitirme tezi. Erişim adresi: https://pharmacy.erciyes.edu.tr/ckfinder/userfiles/files/bitirmeler/Serife_Gunes_Tez.pdf. 20.04.2021
  • Habtemariam, S. (2016). The therapeutic potential of rosemary (Rosmarinus officinalis) diterpenes for Alzheimer’s disease. Evidence-Based Complementary and Alternative Medicine.Erişim adresi: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749867/pdf/ECAM2016-2680409.pdf. Erişim tarihi: 20.04.2021.
  • Hernandez-Perez, T., Gomez-Garcia, M.d.R., Valverde, M.E., Paredes-Lop, O. (2020).Capsicum annuum (hot pepper): An ancient Latin-American crop with outstanding bioactive compounds and nutraceutical potential. A review. Compr Rev Food SciFood Saf , 19, 2972-2993.
  • http://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:260630-2. Erişim tarihi:21.04.2021.
  • Idris, S., Mishra, A., Khushtar, M. (2020). Phytochemical, ethanomedicinal and pharmacological applications of escin from Aesculus hippocastanum L. towards future medicine. J Basic Clin Physiol Pharmacol, 31(5), 20190115. https://doi.org/10.1515/jbcpp-2019-0115.
  • Iseppi, R., Mariani, M., Condo, C., Sabia, C., Messi, P. (2021). Essential oils: a natural weapon against antibiotic-resistant bacteria responsible for nosocomial infections. Antibiotics,10, 417.
  • Islam, N. UI., Jalil, H., Shahid, M., Rauf, A., Muhammad, N., Khan, A., Shah, M.R., Khan, M.A. (2019). Green synthesis and biological activities of gold nanoparticles functionalized with Salix alba.Arabian Journal of Chemistry, 12, 2914-2925.
  • Karousou, R., Deirmentzoglu, S,. (2011). The herbal market of Cyprus: Traditional links and cultural exchanges. J Ethnopharmacol, 133(1), 191–203.
  • Kharwar, R.N., Maurya, A.L., Verma, V.C., Kumar, A, Gond, S.K., Mishra, A. (2012). Diversity and antimicrobial activity of endophytic fungal community isolated from medicinal plant Cinnamomum camphora.Sect. B Biol. Sci, 82(4), 557–565.
  • Lambrecht, F. Y. (2010). Biological activities of stinging netle, Drug Plants Houston (391-409). Awaad, A.S., Govil,J.N., Singh, V.K., Houston:Studium Press LLC.
  • Liu, Y., Liu, J., Zhang, Y. (2019). Research progress on chemical constituents of Zingiber officinale Roscoe. BioMed Res Int. DOI: 10.1155/2019/5370823.
  • Liu Z., Zhang Y., Ou L., Kang L., Liu Y., Lv J., Wei G., Yang B., Yang S., Chen W., Dai X., Li X., Zhou S., Zhang Z., Ma Y., Zou X. (2017). Identification and characterization of novel micrornas for fruit development and quality in hot pepper (Capsicum annuum L.). Gene, 608, 66–72.
  • LiverTox: Clinical and Research Information on DrugInduced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012-. Boswellia serrata. [Updated 2020 Nov 4].Erişim tarihi:10.05.2021.
  • Long, L., Soeken, K., Ernstn, E. (2001). Herbal medicines for the treatment of osteoarthritis: a systematic review, Rheumatology,40 (7), 779–793.
  • Mahendran, G., Rahman, L.U. (2020). Ethnomedicinal, phytochemical and pharmacological updates on Peppermint (Mentha × piperita L.)-A review. Phytother Res. 34(9):2088-2139.
  • Mandal, P., Mısra, T.K., Singh, I.D., Das, J.K., Bhunia, M. (2009). Free-radical-scavenging activity in the inflorescence of European nettle/sisnu ( Urtica dioica L.). J Young Pharmacists, 1(2), 129—135.
  • Marzotto, M.,Arruda-Silva, F., Bellavite, P. (2020). Fibronectin gene up-regulation by Arnica montana in human macrophages: Validation by real-time polymerase chain reaction assay. Homeopathy.109(3), 140-145.
  • Mir, M.A., Sawhney, S.S., Jassal, M.M.S. (2013). Qualitative and quantitative analysis of phytochemicals of Taraxacum officinale. Wudpecker J Pharm Pharmocol, 2(1), 1–5.
  • Mitrović, P.M., Stamenković, O.S., Banković-Ilić, I., Djalović, I. G., Nježić, Z.B., Farooq, M., Veljković, V. B. (2020). White Mustard (Sinapis alba L.) Oil in Biodiesel Production: A Review. Frontiers in Plant Science, 11.
  • Monograph of Boswelliaserrata (2008). Alternative Medicine Review. 13(2), 165-167. Erişim Adresi: http://archive.foundationalmedicinereview.com/publications/13/2/165.pdf. 19.04.2021.
  • Oğuzöncül, A.F., Kurt, O. (2020). Halk sağlığı bakışıyla Türkiye’de kas iskelet hastalıkları .G. Saka. (Ed.). Halk Sağlığı Bakışıyla Türkiye’de Kronik Hastalıklar 1. Baskı. Ankara: Türkiye Klinikleri; 2020. p.52-4.
  • Oliveira, A.I., Pinho, C., Sarmento, B., Dias, A.C.P. (2016). Neuroprotective activity of Hypericum perforatum and its major components. Front. Plant Sci, 7, 1004.
  • Oszmıańskı, J., Kalısz, S., Aneta, W. (2014). The content of phenolic compounds in leaf tissues of white (Aesculus hippocastanum L.) and red horse chestnut (Aesculus carea H.) colonized by the horse chestnut leaf miner (Cameraria ohridella Deschka & Dimić). Molecules.19 (9), 14625-14636.
  • Pandey S., Verma B., Arya P. (2017). A review on constituents, pharmacological activities and medicinal uses of Glycyrrhıza glabra. Univ J Pharma Res, 2(2), 6-11.
  • Peng C., Zhao S.Q., Zhang J., Huang G.Y., Chen L.Y., Zhao F.Y. (2014). Chemical composition, antimicrobial property and microencapsulation of mustard (Sinapis alba) seed essential oil by complex coacervation. Food Chemistry, 165, 560–568.
  • Pereira, V., Dias, C., Vasconcelos, M.C., Rosaa, E., Saavedraa, M.J. (2014). Antibacterial activity and synergistic effects betweenEucalyptus globulusleaf residues (essential oils and extracts) and antibiotics against several ısolates of respiratory tract infections (Pseudomonas aeruginosa). Ind Crops Prod, 52, 1–7.
  • Piątczak, E., Dybowska, M., Płuciennik, E., Kośla, K., Kolniak-Ostek, J.,Kalinowska-Lis, U. (2020). Identification and accumulation of phenolic compounds in the leaves and bark of Salix alba (L.) and their biological potential. Biomolecules, 10(10), 1391.
  • Popova, V.T., Stoyanova M.A., Ivanova, T.A., Stoyanova, A.S., Dimitrova-Dyulgerova, I.Z. (2021). Phytochemical composition of leaves and stems of Solanum nigrum L. and Solanum dulcamara L. (Solanaceae) from Bulgaria. IOP Conf. Ser.: Mater. Sci. Eng. 1031.
  • Qian Mao, Q., Yu Xu, X., Yu Cao, S., You Gan, R., Corke, H., Beta, T., Bin Li, H. (2019). Bioactive compounds and bioactivities of ginger (Zingiber officinale Roscoe). Foods, 8, 185.
  • Raina, R., Verma, P.K., Peshin, R., Kour, H. (2019). Potential of Juniperus communis L. as a nutraceutical in human and veterinary medicine. Heliyon.8(5).
  • Ribeiro, G.dS., Carneiro, A.dA., Martins, D.H.N, Simeoni, L.A., Silveira, D., Magalhaes, P.O. Fonseca-Bazzo, Y.M. (2020). Determination of harpagoside in Harpagophytum procumbens DC tablet’s using analytical method by high performance liquid chromatography. Eclética Química J, 45(1), 47-55.
  • Sarı, A., Özsoy, N., Karahüseyin, S. (2020). Taraxacum farinosum Hausskn. & Bornm. bitkisinin antioksidan aktivite yönünden incelenmesi. Sağlık Bilimlerinde İleri Araştırmalar Derg,3(1), 13-19.
  • Sarıć-kundalıć, B., Dobes, C., Klatte-asselmeyer, V., Saukel j. (2010). Ethnobotanical study on medicinal use of wild and cultivated plants in middle, south and west Bosnia and Herzegovina. J Ethnopharmacol, 131(1), 33-55.
  • Shi X., Dai X., Liu G., Zhang J., Ning G., Bao M. (2010). Cyclic secondary somatic embryogenesis and efficient plant regeneration in Camphor tree (Cinnamomumcamphora L.). In vitro cell.Dev. Biol.-Plant, 46, 117–125.
  • Siddiqui, M.Z. (2011). Boswellia serrata, A potential anti-inflammatory agent: an overview. Indian J Pharm Sci.,73(3): 255–261. Sinisgalli, C., Faraone, I., Vassallo, A., Caddeo, C., Bisaccia, F., Armentano, MF., Milella, L., Ostuni, A. (2020). Phytochemical profile of Capsicum annuumL. cv Senise, incorporation into liposomes, and evaluation of cellular antioxidant activity. Antioxidants (Basel), 15, 9(5):428.
  • Şimsek I., Aytekin F., Yeşilada E., Yıldırımlı S. (2004). An ethnobotanical survey of the Beypazarı, Ayas and Güdül district towns of Ankara province (TURKEY). Economic Botany, 58(4), 705–720.
  • Setty, A., Sigal, L. (2005). Herbal medications commonly used in the practice of rheumatology: mechanisms of action, efficacy, and side effects. Semin Arthritis Rheum.34(6), 773-84.
  • Stanevaa, J., Denkovaa, P., Todorovaa, M., Evstatıeva, L. (2011). Quantitative analysis of sesquiterpene lactones in extract of Arnica montana L. by H-NMR spectroscopy. J Pharm Bio Analys, 54,94–99.
  • Sutha, S., Mohan, V.R., Kumaresan, S., Murugan, C., Athiperumalsamı, T. (2010). Ethnomedicinal plants used by the tribals of Kalakad-Mundanthurai tiger reserve (KMTR), Western Ghats, Tamil Nadu for the treatment of rheumatism. Indian J Trad Know,(9)3, 502-509.
  • Süzgeç Selçuk, S., Eyisan, S. (2012). Türkiye’deki eczanelerde bulunan bitkisel ilaçlar. Marmara Pharm J, 16, 164-180.
  • T.C. Sağlık Bakanlığı Türkiye İlaç ve Tıbbi Cihaz Kurumu (2021). Tıbbi bitki listesi. Erişim adresi:https://www.titck.gov.tr/dinamikmodul/112. 19.04.2021.
  • Uğulu, I. ve Başlar, S. (2010). The determination and fidelity level of medicinal plants used to make traditional Turkish salves. J Alt Comp Med, 16(3), 313–322.
  • Üstü, Y, Uğurlu, M. (2019). Lavantanın tıbbi kullanımı. Ankara Med J,1, 416‐8.
  • Weixlbaumer, V., Draxler, L., Zeitlinger, M., Prant, B. (2020). From St. John’s wort to tomato and from Rhodiola to cranberry, Wien Klin Wochenschr,132,253–259.
  • World Health Organization. (2007). WHO Monographs on Selected Medicinal Plants. Volume 3. Erişim adresi:https://www.who.int/medicines/publications/traditional/MedPlantsMonograph3.pdf. 19.04.2021.
  • World Health Organization. (2009). WHO Monographs on Selected Medicinal Plants. Volume 4. Erişim adresi: https://www.who.int/medicines/areas/traditional/SelectMonoVol4.pdf?ua=1.19.04.2021.
  • World Health Organization. (2010). WHO Monographs on Medicinal Plants Commonly Used in the Newly Independent States. Erişim adresi: https://www.who.int/medicines/areas/traditional/monograph_eng. pdf?ua=1. 20.04.2021.
  • World Health Organization. (‎2013)‎. WHO traditional medicine strategy: 2014-2023. Erişim adresi: https://apps.who.int/iris/handle/10665/92455. Erişim tarihi: 19 Nisan 2021. Xiao, S., Yu, H., Xie, Y., Guo, Y., Fan, J., Yao, W. (2021). The anti-inflammatory potential of Cinnamomum camphora (L.) J.Presl essential oilin vitro and in vivo. Journal of Ethnopharmacology, 267, 113516.
  • Yaman, T., Uyar, A., Kömüroğlu, A.U., Keleş, Ö.F.,Yener, Z. (2019). Chemopreventive efficacy of juniper berry oil (Juniperus communis L.) on azoxymethane-induced colon carcinogenesis in rat. Nutrition and Cancer, 1–14.
  • Yang, F., Chu, T., Zhang, Y., Liu, X., Sun, G., Chen, Z. (2020). Quality assessment of licorice (Glycyrrhiza glabra L.) from different sources by multiple fingerprint profiles combined with quantitative analysis, antioxidant activity and chemometric methods. Food Chem, 324, 126854.
  • Yang, R., Zhou, Q., Wen, C., Hu, J., Li, H., Zhao, M., Zhao, H. (2013). Mustard seed (Sinapis alba Linn) attenuates imiquimod-induced psoriasiform inflammation of BALB/c mice. J Dermatology, 40, 543–552.
  • Yeh, H.Y., Chuang C.H., Chen, H.C., Wan, C.J., Chen, T.L., Lin, L.Y. (2014). Bioactive components analysis of two various gingers (Zingiber officinaleRoscoe) and antioxidant effect of ginger extracts. LWT - Food Sci Tech, 55, 329-334.
  • Yu G., Xiang W., Zhang T., Zeng L., Yang K. ve Li J. (2020). Effectiveness of Boswellia and Boswellia extract for osteoarthritis patients: a systematic review and meta-analysis. BMC Comp Med Therap, 20, 225.
  • Yuan, H., Zhu, M., Guo, W., Jın, L., Chen, W., Brunk, UT., Zhao, M. (2011). Mustard seeds (Sinapis albaLinn) attenuate azoxymethane-induced colon carcinogenesis. Redox Rep.16(1), 38-44.
  • Zhang, R., Ji, Y., Zhang, X., Kennelly, E. J., Long, C. (2020). Ethnopharmacology of Hypericum species in China: A comprehensive review on ethnobotany, phytochemistry and pharmacology. J Ethnopharmacology, 254, 112686.

Herbal Drugs Used in Musculoskeletal Disorders

Yıl 2022, Cilt: 3 Sayı: 2, 31 - 50, 29.04.2022
https://doi.org/10.53445/batd.944819

Öz

The majority of musculoskeletal system disorders are chronic ailments that are not easy to define and cure. The patients tend to complementary treatment methods due to reasons such as inadequacy of medication, pain, decrements in functions, loss of labor force and decrease in quality of life. In our country, in addition to many complementary treatment methods such as acupuncture, prolotherapy, mesotherapy, chiropractic and cupping, physical therapy and balneotherapy, herbal theraphy is also among the frequently used methods which is increasing in popularity. The aim of this study; due to the increasing interest in plants and herbal treatments and the developments in this field, it is to have more comprehensive information about the plants used for treatment in musculoskeletal system disorders that are common in society. For this purpose, the most commonly used plants and the place of these plants in the treatment of musculoskeletal diseases were determined by the exemination of the sources such as scientific books, journals and monographs in the libraries besides the searches made by giving different keywords to various search engines. As well as the relevant literature has been reached, the necessary resources for this study have been provided and presented. In the selection of herbal products, care must be taken to ensure that the product is approved by the Ministry of Health and is used within the knowledge of the physician. In order to evaluate the use of herbal products and their effects on health, there is a need for advanced, longer-term, high-dose, controlled, randomized and double-blind clinical studies with more participants.

Kaynakça

  • Adams, M., Berset, C., Kessler, M., Hamburger, M. (2009). Medicinal herbs for thetreatment of rheumatic disorders-a survey of European herbals from the 16th and 17th century. Journal of Ethnopharmacology, 121, 343–359.
  • Ağalar, H.G., Göğer, F., Demirci, B., Malyer, H., Kırımer N. (2020). Angelica slyvestris var. slyvestris L.: Essential oils and antioxidant activity evaluation. Eskişehir Technical Unıv. J. of Sci. and Tech. A- Appl. Sci. and Eng. 21(1), 39-48. DOI: 10.18038/estubtda.544889.
  • Akbay, P., Başaran, A.A., Undeger, U., Başaran, N. (2003). In vitro immunomodulatory activity of flavonoid glycosides from Urtica dioica L. Phytother Res.17(1), 34–37.
  • Aktaş Şenocak, E., Apaydın Yıldırım, B. (2017). Ratlarda parasetamol ile oluşturulan hepatotoksisite üzerine Taraxacum officinale etanol ekstraktının etkisi. Harran Univ. Vet. Fak. Derg, 6(1), 11-18.
  • Alp, H. (2020). Konya-Akyokuş yöresinde yetişen sarı kantaron (Hypericum perforatum) bitkisinin fitokimyasal analizi. Necmettin Erbakan Univ Sağlık Bilim Derg, 2 (2), 1-7.
  • Alp, H., Şen, M. (2020). Investigation of the Components of Lavender Plant Grown in Konya-Turkey Region. J Tradit Complem Med, 3 (2), 166-70.
  • Altay, B., Gönener, H.D., İslam, K., Göv, P. (2010). Fizik tedavi alan hastaların yaşam kalitesinin değerlendirilmesi. Gaziantep Tıp Derg,16(2), 29-35.
  • Alvarez-Nemegyei, J.,Bautista-Botello, A., Dávila-Velázquez, J. (2009). Association of complementary or alternative medicine use with quality of life, functional status or cumulated damage in chronic rheumatic diseases, Clin Rheumatol, 28, 547–551.
  • Avan, M. (2021). Türkiye’de ve dünyada görülen önemli tıbbi ve aromatik bitkiler, özellikleri ve hastalıkları üzerine araştırmalar. Uluslararası Doğu Anadolu Fen Mühend Tasar Derg,3(1), 129-156.
  • Axmann, S., Hummel, K., Nöbauer, K., Razzazi-Fazeli, E., Zitterl-Eglseer, K. (2019). Pharmacokinetics of harpagoside in horses after intragastric administration of a Devil’s claw (Harpagophytum procumbens) extract.J vet Pharmacol Therap.42:37–44.
  • Ayan, A.K., Çalışkan, Ö., Çırak, C.T. (2006). Isırgan otu (Urtica spp.)’nun ekonomik önemi ve tarımı. OMÜ Zir Fak Derg, 21(3), 357-363.
  • Azman, N.A.M., Skowyra, M., Muhammed, K., Gallego, M.G., Almajano, M.P. (2017). Evaluation of the antioxidant activity of Betula pendula leaves extract and its effects on model foods. J Pharm Biol, 55 (1), 912-919.
  • Bahmani M, Rafieian-Kopaei M, Jeloudari M, Eftekhari Z, Delfan B, Zargaran A, Forouzan S. (2014). A review of the health effects and uses of drugs of plant licorice (Glycyrrhiza glabra L.) in Iran. Asian Pac J Trop Dis, 4(2), 847-849.
  • Batiha, G.E.S., Beshbishy, A.M., El-Mleeh, A., Abdel-Daim, M.M., Devkota, H.P. (2020). Traditional uses, bioactive chemical constituents, and pharmacological and toxicological activities of Glycyrrhiza glabra L. (Fabaceae). Biomolecules,10, 352.
  • Baytop, T. (1999). Türkiye’de bitkiler ile tedavi. İstanbul:Nobel Tıp Kitabevleri. “2. Baskı”.
  • Bhat, Z.A., Kumar, D., Shah, M.Y. (2011). Angelica archangelica Linn. is an angel on earth for the treatment of diseases. Int J Nutr, 1(1), 36-50.
  • Bilenler, T., Gökbulut, İ. (2019). Hastane patojenlerinin ticari uçucu yağlara karşı hassasiyetlerinin belirlenmesi. GÜFBED/GUSTIJ. 9 (3), 716-723.
  • Boulekbache-Makhlouf, L., Slimanı, S., Madai, K. (2013). Total phenolic content, antioxidant and antibacterial activities of fruits of Eucalyptus globulus cultivated in Algeria. Ind Crops Prod, 41, 85–89.
  • Brussell, D.E. (2004). Medicinal plants of Mt. Pelion, Greece. Economic Botany, 58 (Supplement), 174–202.
  • Calapai, G., Minciullo, P.L., Miroddi, M., Chinou, I., Gangemi, S., Schmidt, R.J. (2016). Contact dermatitis as an adverse reaction to some topically used European herbal medicinal products–part 3:Mentha × piperita – Solanum dulcamara. Contact Dermatitis,74(3), 131–144.
  • Chen, J., Tang, C., Zhang, R., Ye, S., Zhao, Z., Huang, Y., Yang, D. (2020). Metabolomics analysis to evaluate the antibacterial activity of the essential oil from the leaves of Cinnamomum camphora (Linn.) Presl. J Ethnopharmacol, 253, 112652.
  • Craciunescu, O., Constantin, D., Gaspar, A., Toma, L., Utoiu, E., Moldovan, L. (2012). Evaluation of antioxidant and cytoprotective activities of Arnica montana L. and Artemisia absinthium L. ethanolic extracts. Chem Cent J, 6,97.
  • Cukanovic, J., Tesevic, V., Jadranin, M., Jubojevic, M., Mladenovic, E., Kostic, S. (2020). Horse chestnut (Aesculus hippocastanumL.) seed fatty acids, flavonoids and heavy metals plasticity to different urban environments. Bio Syst Eco, 89, 103980.
  • Çelik, S.A., Ayran, İ. (2020). Antioksidan kaynağı olarak bazı tıbbi ve aromatik bitkiler. Türk Bilimsel Derlemeler Derg, 13(2), 115-125.
  • Çırak, C., Kurt, D.(2014). Önemli tıbbi bitkiler olarak Hypericum türleri. Anadolu, 24 (1), 42 – 58.
  • Çolak, S., Çömlekçioğlu, N., Aygan, A. (2020). Urtica dioica L.özütlerinin antioksidan ve antimikrobiyal aktivitelerinin incelenmesi. Eurasian J Bio Chem Sci.3(1), 206-212.
  • De Athayde, AE., de Araujo, CES., Sandjo, LP., Biavatti, MW. (2021). Metabolomic analysis among ten traditional "Arnica" (Asteraceae) from Brazil. J Ethnopharmacol. 265, 113149.
  • De Macedo, L.M., Santos, É.M. dos, Militão, L., Tundisi, L.L., Ataide, J.A., Souto, E.B., Mazzola, P.G. (2020). Rosemary (Rosmarinus officinalis L., syn Salvia rosmarinus spenn.) and Its Topical Applications: A Review. Plants, 9(5), 651. doi:10.3390/plants9050651.
  • De Oliveira, J.R., Camargo, S.E.A., de Oliveira, L.D. (2019). Rosmarinus officinalis L. (rosemary) as therapeutic and prophylactic agent. J Bio Sci, 26,5.
  • Di Sottoa, A., Vecchiatoa, M., Abetea, L., Toniolob, C., Giustic, A.M., Manninad, L., Locatellie, M., Nicolettib, M., Di Giacomo, S. (2018).Capsicum Annuum L. var. Cornetto di Pontecorvo PDO: Polyphenolic Profile and in vitro Biological Activities. J Func Foods, 40, 679–691.
  • Dobrowolska, I., Andrade, G.M., Clapham, D., Egertsdotter, U. (2017). Histological analysis reveals the formation of shoots rather than embryos in regenerating cultures of Eucalyptus globulus. Plant Cell Tiss Organ Cult, 128, 319–326.
  • Düzgüner, V., Erbil, V. (2020). Ardahan yöresinde yetişen kılıç otu bitkisinin (Hypericum perforatum) antimikrobiyal ve antioksidan etkilerinin araştırılması. Türk Tarım ve Doğa Bilim Derg, 7(1), 27–31.
  • El Beyrouthy, M., Arnold, N., Delelis-Dusollier, A., Dupont, F. (2008). Plants used as remedies antirheumatic and antineuralgic in the traditional medicine of Lebanon. J Ethnopharmacol, 120, 315– 334.
  • El Omari, N., Ezzahrae Guaouguaou, F., El Menyiy, N., Benali, T., Aanniz, T., Chamkhi, I., Bouyahya, A. (2021). Phytochemical and biological activities of Pinus halepensis Mill., and their ethnomedicinal use. J Ethnopharmacol. 268:113661.
  • Ezberci, F., Ünal, E. (2018). Hemoroidal hastalığın tedavisinde Aesculus Hippocastanum (Aescin, at kestanesi) kullanımı. Turk J Colorectal Dis, 28, 54-57.
  • Galindo-Jaıme, L., González-Espinosa, M., Quintana-Ascencio, P., García-Barrios, L. (2002). Tree composition and structure in disturbed stands with varying dominance byPinus spp. in the highlands of Chiapas, México. Plant Ecology, 162, 259–272.
  • Güneş, DŞ. (2011). Romatizmal hastalıkların tedavisinde sıklıkla kullanılan bitkiler ve bitkisel ürünler. Erciyes Üniversitesi eczacılık fakültesi farmakognozi ABD bitirme tezi. Erişim adresi: https://pharmacy.erciyes.edu.tr/ckfinder/userfiles/files/bitirmeler/Serife_Gunes_Tez.pdf. 20.04.2021
  • Habtemariam, S. (2016). The therapeutic potential of rosemary (Rosmarinus officinalis) diterpenes for Alzheimer’s disease. Evidence-Based Complementary and Alternative Medicine.Erişim adresi: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749867/pdf/ECAM2016-2680409.pdf. Erişim tarihi: 20.04.2021.
  • Hernandez-Perez, T., Gomez-Garcia, M.d.R., Valverde, M.E., Paredes-Lop, O. (2020).Capsicum annuum (hot pepper): An ancient Latin-American crop with outstanding bioactive compounds and nutraceutical potential. A review. Compr Rev Food SciFood Saf , 19, 2972-2993.
  • http://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:260630-2. Erişim tarihi:21.04.2021.
  • Idris, S., Mishra, A., Khushtar, M. (2020). Phytochemical, ethanomedicinal and pharmacological applications of escin from Aesculus hippocastanum L. towards future medicine. J Basic Clin Physiol Pharmacol, 31(5), 20190115. https://doi.org/10.1515/jbcpp-2019-0115.
  • Iseppi, R., Mariani, M., Condo, C., Sabia, C., Messi, P. (2021). Essential oils: a natural weapon against antibiotic-resistant bacteria responsible for nosocomial infections. Antibiotics,10, 417.
  • Islam, N. UI., Jalil, H., Shahid, M., Rauf, A., Muhammad, N., Khan, A., Shah, M.R., Khan, M.A. (2019). Green synthesis and biological activities of gold nanoparticles functionalized with Salix alba.Arabian Journal of Chemistry, 12, 2914-2925.
  • Karousou, R., Deirmentzoglu, S,. (2011). The herbal market of Cyprus: Traditional links and cultural exchanges. J Ethnopharmacol, 133(1), 191–203.
  • Kharwar, R.N., Maurya, A.L., Verma, V.C., Kumar, A, Gond, S.K., Mishra, A. (2012). Diversity and antimicrobial activity of endophytic fungal community isolated from medicinal plant Cinnamomum camphora.Sect. B Biol. Sci, 82(4), 557–565.
  • Lambrecht, F. Y. (2010). Biological activities of stinging netle, Drug Plants Houston (391-409). Awaad, A.S., Govil,J.N., Singh, V.K., Houston:Studium Press LLC.
  • Liu, Y., Liu, J., Zhang, Y. (2019). Research progress on chemical constituents of Zingiber officinale Roscoe. BioMed Res Int. DOI: 10.1155/2019/5370823.
  • Liu Z., Zhang Y., Ou L., Kang L., Liu Y., Lv J., Wei G., Yang B., Yang S., Chen W., Dai X., Li X., Zhou S., Zhang Z., Ma Y., Zou X. (2017). Identification and characterization of novel micrornas for fruit development and quality in hot pepper (Capsicum annuum L.). Gene, 608, 66–72.
  • LiverTox: Clinical and Research Information on DrugInduced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012-. Boswellia serrata. [Updated 2020 Nov 4].Erişim tarihi:10.05.2021.
  • Long, L., Soeken, K., Ernstn, E. (2001). Herbal medicines for the treatment of osteoarthritis: a systematic review, Rheumatology,40 (7), 779–793.
  • Mahendran, G., Rahman, L.U. (2020). Ethnomedicinal, phytochemical and pharmacological updates on Peppermint (Mentha × piperita L.)-A review. Phytother Res. 34(9):2088-2139.
  • Mandal, P., Mısra, T.K., Singh, I.D., Das, J.K., Bhunia, M. (2009). Free-radical-scavenging activity in the inflorescence of European nettle/sisnu ( Urtica dioica L.). J Young Pharmacists, 1(2), 129—135.
  • Marzotto, M.,Arruda-Silva, F., Bellavite, P. (2020). Fibronectin gene up-regulation by Arnica montana in human macrophages: Validation by real-time polymerase chain reaction assay. Homeopathy.109(3), 140-145.
  • Mir, M.A., Sawhney, S.S., Jassal, M.M.S. (2013). Qualitative and quantitative analysis of phytochemicals of Taraxacum officinale. Wudpecker J Pharm Pharmocol, 2(1), 1–5.
  • Mitrović, P.M., Stamenković, O.S., Banković-Ilić, I., Djalović, I. G., Nježić, Z.B., Farooq, M., Veljković, V. B. (2020). White Mustard (Sinapis alba L.) Oil in Biodiesel Production: A Review. Frontiers in Plant Science, 11.
  • Monograph of Boswelliaserrata (2008). Alternative Medicine Review. 13(2), 165-167. Erişim Adresi: http://archive.foundationalmedicinereview.com/publications/13/2/165.pdf. 19.04.2021.
  • Oğuzöncül, A.F., Kurt, O. (2020). Halk sağlığı bakışıyla Türkiye’de kas iskelet hastalıkları .G. Saka. (Ed.). Halk Sağlığı Bakışıyla Türkiye’de Kronik Hastalıklar 1. Baskı. Ankara: Türkiye Klinikleri; 2020. p.52-4.
  • Oliveira, A.I., Pinho, C., Sarmento, B., Dias, A.C.P. (2016). Neuroprotective activity of Hypericum perforatum and its major components. Front. Plant Sci, 7, 1004.
  • Oszmıańskı, J., Kalısz, S., Aneta, W. (2014). The content of phenolic compounds in leaf tissues of white (Aesculus hippocastanum L.) and red horse chestnut (Aesculus carea H.) colonized by the horse chestnut leaf miner (Cameraria ohridella Deschka & Dimić). Molecules.19 (9), 14625-14636.
  • Pandey S., Verma B., Arya P. (2017). A review on constituents, pharmacological activities and medicinal uses of Glycyrrhıza glabra. Univ J Pharma Res, 2(2), 6-11.
  • Peng C., Zhao S.Q., Zhang J., Huang G.Y., Chen L.Y., Zhao F.Y. (2014). Chemical composition, antimicrobial property and microencapsulation of mustard (Sinapis alba) seed essential oil by complex coacervation. Food Chemistry, 165, 560–568.
  • Pereira, V., Dias, C., Vasconcelos, M.C., Rosaa, E., Saavedraa, M.J. (2014). Antibacterial activity and synergistic effects betweenEucalyptus globulusleaf residues (essential oils and extracts) and antibiotics against several ısolates of respiratory tract infections (Pseudomonas aeruginosa). Ind Crops Prod, 52, 1–7.
  • Piątczak, E., Dybowska, M., Płuciennik, E., Kośla, K., Kolniak-Ostek, J.,Kalinowska-Lis, U. (2020). Identification and accumulation of phenolic compounds in the leaves and bark of Salix alba (L.) and their biological potential. Biomolecules, 10(10), 1391.
  • Popova, V.T., Stoyanova M.A., Ivanova, T.A., Stoyanova, A.S., Dimitrova-Dyulgerova, I.Z. (2021). Phytochemical composition of leaves and stems of Solanum nigrum L. and Solanum dulcamara L. (Solanaceae) from Bulgaria. IOP Conf. Ser.: Mater. Sci. Eng. 1031.
  • Qian Mao, Q., Yu Xu, X., Yu Cao, S., You Gan, R., Corke, H., Beta, T., Bin Li, H. (2019). Bioactive compounds and bioactivities of ginger (Zingiber officinale Roscoe). Foods, 8, 185.
  • Raina, R., Verma, P.K., Peshin, R., Kour, H. (2019). Potential of Juniperus communis L. as a nutraceutical in human and veterinary medicine. Heliyon.8(5).
  • Ribeiro, G.dS., Carneiro, A.dA., Martins, D.H.N, Simeoni, L.A., Silveira, D., Magalhaes, P.O. Fonseca-Bazzo, Y.M. (2020). Determination of harpagoside in Harpagophytum procumbens DC tablet’s using analytical method by high performance liquid chromatography. Eclética Química J, 45(1), 47-55.
  • Sarı, A., Özsoy, N., Karahüseyin, S. (2020). Taraxacum farinosum Hausskn. & Bornm. bitkisinin antioksidan aktivite yönünden incelenmesi. Sağlık Bilimlerinde İleri Araştırmalar Derg,3(1), 13-19.
  • Sarıć-kundalıć, B., Dobes, C., Klatte-asselmeyer, V., Saukel j. (2010). Ethnobotanical study on medicinal use of wild and cultivated plants in middle, south and west Bosnia and Herzegovina. J Ethnopharmacol, 131(1), 33-55.
  • Shi X., Dai X., Liu G., Zhang J., Ning G., Bao M. (2010). Cyclic secondary somatic embryogenesis and efficient plant regeneration in Camphor tree (Cinnamomumcamphora L.). In vitro cell.Dev. Biol.-Plant, 46, 117–125.
  • Siddiqui, M.Z. (2011). Boswellia serrata, A potential anti-inflammatory agent: an overview. Indian J Pharm Sci.,73(3): 255–261. Sinisgalli, C., Faraone, I., Vassallo, A., Caddeo, C., Bisaccia, F., Armentano, MF., Milella, L., Ostuni, A. (2020). Phytochemical profile of Capsicum annuumL. cv Senise, incorporation into liposomes, and evaluation of cellular antioxidant activity. Antioxidants (Basel), 15, 9(5):428.
  • Şimsek I., Aytekin F., Yeşilada E., Yıldırımlı S. (2004). An ethnobotanical survey of the Beypazarı, Ayas and Güdül district towns of Ankara province (TURKEY). Economic Botany, 58(4), 705–720.
  • Setty, A., Sigal, L. (2005). Herbal medications commonly used in the practice of rheumatology: mechanisms of action, efficacy, and side effects. Semin Arthritis Rheum.34(6), 773-84.
  • Stanevaa, J., Denkovaa, P., Todorovaa, M., Evstatıeva, L. (2011). Quantitative analysis of sesquiterpene lactones in extract of Arnica montana L. by H-NMR spectroscopy. J Pharm Bio Analys, 54,94–99.
  • Sutha, S., Mohan, V.R., Kumaresan, S., Murugan, C., Athiperumalsamı, T. (2010). Ethnomedicinal plants used by the tribals of Kalakad-Mundanthurai tiger reserve (KMTR), Western Ghats, Tamil Nadu for the treatment of rheumatism. Indian J Trad Know,(9)3, 502-509.
  • Süzgeç Selçuk, S., Eyisan, S. (2012). Türkiye’deki eczanelerde bulunan bitkisel ilaçlar. Marmara Pharm J, 16, 164-180.
  • T.C. Sağlık Bakanlığı Türkiye İlaç ve Tıbbi Cihaz Kurumu (2021). Tıbbi bitki listesi. Erişim adresi:https://www.titck.gov.tr/dinamikmodul/112. 19.04.2021.
  • Uğulu, I. ve Başlar, S. (2010). The determination and fidelity level of medicinal plants used to make traditional Turkish salves. J Alt Comp Med, 16(3), 313–322.
  • Üstü, Y, Uğurlu, M. (2019). Lavantanın tıbbi kullanımı. Ankara Med J,1, 416‐8.
  • Weixlbaumer, V., Draxler, L., Zeitlinger, M., Prant, B. (2020). From St. John’s wort to tomato and from Rhodiola to cranberry, Wien Klin Wochenschr,132,253–259.
  • World Health Organization. (2007). WHO Monographs on Selected Medicinal Plants. Volume 3. Erişim adresi:https://www.who.int/medicines/publications/traditional/MedPlantsMonograph3.pdf. 19.04.2021.
  • World Health Organization. (2009). WHO Monographs on Selected Medicinal Plants. Volume 4. Erişim adresi: https://www.who.int/medicines/areas/traditional/SelectMonoVol4.pdf?ua=1.19.04.2021.
  • World Health Organization. (2010). WHO Monographs on Medicinal Plants Commonly Used in the Newly Independent States. Erişim adresi: https://www.who.int/medicines/areas/traditional/monograph_eng. pdf?ua=1. 20.04.2021.
  • World Health Organization. (‎2013)‎. WHO traditional medicine strategy: 2014-2023. Erişim adresi: https://apps.who.int/iris/handle/10665/92455. Erişim tarihi: 19 Nisan 2021. Xiao, S., Yu, H., Xie, Y., Guo, Y., Fan, J., Yao, W. (2021). The anti-inflammatory potential of Cinnamomum camphora (L.) J.Presl essential oilin vitro and in vivo. Journal of Ethnopharmacology, 267, 113516.
  • Yaman, T., Uyar, A., Kömüroğlu, A.U., Keleş, Ö.F.,Yener, Z. (2019). Chemopreventive efficacy of juniper berry oil (Juniperus communis L.) on azoxymethane-induced colon carcinogenesis in rat. Nutrition and Cancer, 1–14.
  • Yang, F., Chu, T., Zhang, Y., Liu, X., Sun, G., Chen, Z. (2020). Quality assessment of licorice (Glycyrrhiza glabra L.) from different sources by multiple fingerprint profiles combined with quantitative analysis, antioxidant activity and chemometric methods. Food Chem, 324, 126854.
  • Yang, R., Zhou, Q., Wen, C., Hu, J., Li, H., Zhao, M., Zhao, H. (2013). Mustard seed (Sinapis alba Linn) attenuates imiquimod-induced psoriasiform inflammation of BALB/c mice. J Dermatology, 40, 543–552.
  • Yeh, H.Y., Chuang C.H., Chen, H.C., Wan, C.J., Chen, T.L., Lin, L.Y. (2014). Bioactive components analysis of two various gingers (Zingiber officinaleRoscoe) and antioxidant effect of ginger extracts. LWT - Food Sci Tech, 55, 329-334.
  • Yu G., Xiang W., Zhang T., Zeng L., Yang K. ve Li J. (2020). Effectiveness of Boswellia and Boswellia extract for osteoarthritis patients: a systematic review and meta-analysis. BMC Comp Med Therap, 20, 225.
  • Yuan, H., Zhu, M., Guo, W., Jın, L., Chen, W., Brunk, UT., Zhao, M. (2011). Mustard seeds (Sinapis albaLinn) attenuate azoxymethane-induced colon carcinogenesis. Redox Rep.16(1), 38-44.
  • Zhang, R., Ji, Y., Zhang, X., Kennelly, E. J., Long, C. (2020). Ethnopharmacology of Hypericum species in China: A comprehensive review on ethnobotany, phytochemistry and pharmacology. J Ethnopharmacology, 254, 112686.
Toplam 91 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Klinik Tıp Bilimleri
Bölüm Derleme Makaleleri
Yazarlar

Özlem Aynaoğlu Hakverdi 0000-0002-1503-4399

Alev Önder 0000-0002-9088-1045

Yayımlanma Tarihi 29 Nisan 2022
Yayımlandığı Sayı Yıl 2022 Cilt: 3 Sayı: 2

Kaynak Göster

APA Aynaoğlu Hakverdi, Ö., & Önder, A. (2022). Kas-İskelet Sistemi Rahatsızlıklarında Kullanılan Bitkisel Droglar. Bütünleyici Ve Anadolu Tıbbı Dergisi, 3(2), 31-50. https://doi.org/10.53445/batd.944819

Bütünleyici ve Anadolu Tıbbı Dergisi

Journal of Integrative and Anatolian Medicine