Yüksek Performanslı Sıvı Kromatografisi ile Origanum bilgeri'deki Biyoaktif Bileşiklerin Kantitatif Analizi

Yıl 2022, Cilt: 4 Sayı: 1, 15 - 20, 15.12.2022

Ramazan Erenler , Esma Nur Geçer , Mehmet Hakkı Alma , İbrahim Demirtas

https://doi.org/10.53445/batd.1210373

Cited By: 2

Öz

Origanum cinsi önemli biyoaktif bileşikler içeren aromatik ve tıbbi bir bitkidir. Origanum türleri yıllardır halk ilacı olarak kullanılmaktadır. Bu çalışmada, Origanum bilgeri P.H. Davis sırasıyla heksan ve metanol ile ekstrakte edildi, metanol ekstraktı, Yüksek Performanslı Sıvı Kromatografisi ile biyoaktif bileşiklerin kantitatif analizi için kullanıldı. Ana ürün olarak rosmarinik asit bulundu (26.61 mg/g ekstrakt). Diğer ana bileşikler kateşin hidrit (5,65 mg/g ekstrakt), trans-sinnamik asit (2,65 mg/g ekstrakt), resveratrol (1,33 mg/g ekstrakt) olarak tespit edildi. Sonuç olarak, Origanum bilgeri ilaç geliştirme ve gıda için değerli bir materyal olabilme potansiyeline sahiptir.

Anahtar Kelimeler

Origanum bilgeri, Doğal ürünler, Kantitatif analiz

Quantitative Analysis of Bioactive Compounds by High‑Performance Liquid Chromatography in Origanum bilgeri

Öz

Origanum genus is an aromatic and medicinal plant with significant bioactive compounds. Origanum species have been used as a folk medicine for years. In this study, the aerial part of Origanum bilgeri P.H. Davis was extracted with hexane and methanol successively, the methanol extract was used for quantitative analysis of bioactive compounds by High‑Performance Liquid Chromatography. Rosmarinic acid was found as a major product (26.61 mg/g extract). The other major compounds were detected as catechin hydride (5.65 mg/g extract), trans-cinnamic acid (2.65 mg/g extract), and resveratrol (1.33 mg/g extract). Consequently, Origanum bilgeri may be a valuable material for drug development and food.

Anahtar Kelimeler

Origanum bilgeri, Natural products, Quantitative analysis

Kaynakça

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