Gebelikte Hipofizer Hastalıklar ve Hemşirelik Bakımı

Yıl 2022, Cilt: 4 Sayı: 3, 272 - 277, 26.12.2022

Elif Balkan , Meltem Mecdi Kaydırak , Nevin Hotun Şahin

https://doi.org/10.46413/boneyusbad.1159056

Öz

Hipofiz bezi, ürettiği çeşitli hormonlar nedeniyle vücut üzerinde oldukça önemli etkilere sahiptir. Gebelik sürecinde hipofizin anatomik ve fizyolojik değişikliklere uğramasıyla hipofizer hastalıkların tanılanmasında çeşitli zorluklar yaşanmaktadır. Başlıca hipofizer hastalıklar prolaktinoma, akromegali, Cushing Sendromu, Sheehan’s sendromu ve Lenfositik hipofizittir. Bu hastalıklarda gebelik nadir görüldüğünden tanı genellikle gebelikten önce konmaktadır. Buna rağmen prekonsepsiyonel dönemden itibaren hipofizer hastalıklarda etkin bir bakım gerekmektedir. Çok çeşitli maternal-fetal komplikasyonlara neden olan bu hastalıklarda multidisipliner bir yaklaşım esastır. Bu multidisipliner ekipte önemli bir rol oynayan hemşireler, hipofiz hastalıklarının temel belirtilerini iyi bilmeli ve gebelere verdikleri bakımda hastalığa özgü bireyselleştirilmiş bir bakımdan yararlanmalıdır.

Anahtar Kelimeler

Hipofizer hastalık, Gebelik, Hemşirelik, Bakım

Destekleyen Kurum

Yoktur

Proje Numarası

Yoktur

Teşekkür

Yoktur

Pituitary Diseases and Nursing Care During Pregnancy

Öz

The pituitary gland has very important effects on the body due to the various hormones it produces. Various difficulties are experienced in the diagnosis of pituitary diseases as the pituitary undergoes anatomical and physiological changes during pregnancy. Major pituitary diseases are prolactinoma, acromegaly, Cushing's syndrome, Sheehan's syndrome and Lymphocytic hypophysitis. Since pregnancy is rare in these diseases, the diagnosis is usually made before pregnancy. Despite this, effective care is required in pituitary diseases from the preconceptional period. A multidisciplinary approach is essential in these diseases that cause a wide variety of maternal-fetal complications. Nurses, who play an important role in this multidisciplinary team, should know the basic symptoms of pituitary diseases well and should benefit from an individualized care specific to the disease in the care they give to pregnant women.

Anahtar Kelimeler

Pituitary disease, Pregnancy, Nursing, Care

Proje Numarası

Yoktur

Kaynakça

• Alatzoglou, K.S., Gregory, L.C., Dattani, M. (2020). Development of the Pituitary Gland. Comprehensive Physiology, 10(2), 389-413.
• Bensing, S., Hulting, A.L., Hoog, A., Ericson, K., Kampe, O. (2007). Lymphocytic hypophysitis: report of two biopsy-proven cases and one suspected case with pituitary autoantibodies. Journal of Endocrinological Investigation, 30(2), 153–162. doi:10.1007/BF03347415.
• Caron, P., Broussaud, S., Bertherat, J., Borson-Chazot, F., Brue, T., Cortet-Rudelli, C., … Chanson, P. (2010). Acromegaly and pregnancy: a retrospective multicenter study of 59 pregnancies in 46 women. The Journal of Clinical Endocrinology & Metabolism, 95(10), 4680-4687. doi:10.1210/jc.2009-2331.
• Cheng, V., Faiman, C., Kennedy, L., Khoury, F., Hatipoglu, B., Weil, R., … Hamrahian, A. (2012). Pregnancy and Acromegaly: a review. Pituitary, 15:59-63. doi: 10.1007/s11102-011-0330-3.
• Chrisoulidou, A., Boudina, M., Karavitaki, N., Bili, E., Wass, J. (2015). Pituitary disorders in pregnancy. Hormones, 14(1), 70-80. doi:10.1007/BF03401382.
• Cozzi, R., Attanasio, R., Barausse, M. (2006). Pregnancy in acromegaly: a one-center experience. European Journal of Endocrinology, 155(2), 279-284. doi:10.1530/eje.1.02215.
• Feldt-Rasmussen, U., Mathiesen, E.R. (2011). Endocrine disorders in pregnancy: physiological and hormonal aspects of pregnancy. Best Practice & Research Clinical Endocrinology & Metabolism, 25(6), 875-884. doi:10.1016/j.beem.2011.07.004.
• Grynberg, M., Salenave, S., Young, J., Chanson, P. (2010). Female gonadal function before and after treatment of acromegaly. The Journal of Clinical Endocrinology & Metabolism, 95(10), 4518-4525. doi:10.1210/jc.2009-2815
• Karaca, Z., Kelestimur, F. (2010). Pregnancy and other pituitary disorders (including GH deficiency). Best Practice & Research Clinical Endocrinology & Metabolism, 25(6), 897-910. doi:10.1016/j.beem.2011.07.006
• Karaca, Z., Tarıverdi, F., Unluhizarci, K., Kelestimur, F. (2010). Pregnancy and pituitary disorders. European Journal of Endocrinology, 162(3), 453-475. doi:10.1530/EJE-09-0923.
• Kelestimur, F. (2003). Sheehan’s syndrome. Pituitary, 6(4), 181-188. doi:10.1023/b:pitu.0000023425.20854.8e.
• Kelestimur, F., Jonsson, P., Molvalilar, S., Gomez, J.M., Auernhammer, C.J., Colak, R., … Goth, M.I. (2005). Sheehan’s syndrome: Baseline characteristics and effect of 2 years of growth hormone replacement therapy in 91 patients in KIMS-Pfizer International Metabolic Database. European Journal of Endocrinology, 152(4), 581-587. doi:10.1530/eje.1.01881.
• Laway, B.A., Mir, S.A. (2013). Pregnancy and pituitary disorders: Challenges in diagnosis and management. Indian Journal of Endocrinology and Metabolism, 17(6), 996-1004. doi: 10.4103/2230-8210.122608
• Melikoğlu, S.E., Özakgül, A.A., Kaya, H. (2018). Nursing Care of an Individual with Pituitary Tumor. The Journal of Neurological and Neurosurgical Nursing, 7(2), 86-92. doi: 10.15225/pnn.2018.7.2.6
• Melmed, S., Casanueva, F.F., Klibanski, A., Bronstein, M.D., Chanson, P., Lamberts, S.W., … Giustina, A. (2013). A consensus on the diagnosis and treatment of acromegaly complications. Pituitary, 16(3), 294-302. doi:10.1007/s11102-012-0420-x.
• Muhammad, A., Neggers, S.J., van der Lely, A.J. (2017). Pregnancy and acromegaly. Pituitary, 20(1), 179-184. doi:10.1007/s11102-016-0740-3
• O’Herlihy, C. (1980). Pregnancy in an acromegalic after bromocriptine therapy. Irish Journal of Medical Science, 149(7), 281-282. doi:10.1007/BF02939155
• Schury MP, Adigun R. StatPearls [Internet]. StatPearls Publishing; Treasure Island (FL): Sep 8, 2021. Sheehan Syndrome.
• Valassi, E. (2021). Pituitary disease and pregnancy. Endocrinología, Diabetes y Nutrición, 68(3), 184-195. doi:10.1016/j.endien.2020.07.0021