Investigation of Patients Undergoing Left Main Coronary Stent Implantation in Our Center for Major Adverse Cardiac Events

Yıl 2022, , 473 - 479, 30.12.2022

Sercan Çayırlı , Ufuk Eryılmaz , Sevil Gülaştı

https://doi.org/10.34087/cbusbed.1141744

Öz

Objective: Despite many studies in the literature, there is no definite decision in the treatment of the patients who diagnosed critical stenosis in the left main coronary artery. We aimed to retrospectively scan the patients who underwent left main coronary artery stent implantation in our center in the last five years, compare them with the patients who underwent coronary artery bypass graft, and share the results of our own center.
Materials and Methods: Patients with suspected coronary artery disease who underwent invasive coronary angiography as a result of various tests and underwent stent implantation due to left main coronary artery critical stenosis (31 patients) and coronary artery bypass graft, due to left main coronary stenosis or three-vessel disease (34 patients) were included in the study. Patients were compared in terms of death, stroke, myocardial infarction, and revascularization.
Results: While the mean age was 68.77±11.46 years in the percutaneous coronary intervention group and 72.82±8.81 years in the coronary artery bypass graft group (p 0.110). Demographic data of the two groups were similar and no significant difference was found between the groups. A statistically significant difference was found between the two groups in terms of use calcium channel blockers (p 0.049) and clopidogrel (p 0.001). No statistically significant difference was observed between the groups in terms of stroke (P 0.981), need for revascularization (0.614), death (P 0.21), and myocardial infarction (0.071).
Conclusion: There is no difference in the application of percutaneous coronary intervention and coronary artery bypass graft in patients with left main coronary artery lesions in terms of stroke, revascularization, death and myocardial infarction. Further studies with larger cohorts are needed for validation.

Anahtar Kelimeler

CABG, PCI, mortality

Merkezimizde Sol Ana Koroner Stent İmplantasyonu Uygulanan Hastaların Major Advers Kardiyak Olaylar Açısından İncelenmesi

Öz

Giriş ve Amaç: Literatürde yer alan birçok çalışmaya rağmen sol ana koroner arterde kritik darlık saptanan hastaların tedavisinde kesin olarak varılan bir karar bulunmamaktadır. Merkezimizde son beş yıl içerisinde sol ana koroner arter stent implantasyonu yapılan hastaları retrospektif olarak tarayarak koroner arter bypass greft uygulanan hastalar ile kıyaslayıp kendi merkezimizin sonuçlarını paylaşmayı hedefledik.
Gereç ve Yöntemler: Koroner arter hastalığı şüphesiyle çeşitli testler sonucunda invaziv koroner anjiyografi uygulanıp sol ana koroner arter kritik darlığı nedeniyle stent implantasyonu (31 hasta) ve ana koroner darlığı ya da üç damar hastalığı nedeniyle bypass kararı verilen (34 hasta) hastalar çalışmaya dahil edildi. Ölüm, inme, miyokart enfarktüsü, tekrarlayan revaskülarizasyon açısından hastalar kıyaslandı.
Bulgular: Perkutan koroner girişim grubunda ortalama yaş 68,77±11,46, koroner arter bypass greft grubunda ise 72,82±8,81 olarak izlenmişken p değeri 0,110 olarak saptanmıştır. İki grubun demografik verileri benzer olup gruplar arasında anlamlı fark saptanmamıştır. İki grup arasında kalsiyum kanal blokörü (p 0.049) ve klopidogrel (p 0.001) kullanımı açısından istatistiki anlamlı fark saptanmıştır. Gruplar arasında inme (P 0,981), tekrarlayan revaskülarizasyon ihtiyacı (0,614), ölüm (P 0,21) ve miyokart enfarktüsü (0,071) açısından istatistiki açıdan anlamlı bir fark gözlenmemiştir.
Sonuç: Sol ana koroner arter lezyonu olan hastalarda perkutan koroner girişim ve koroner arter bypass greft uygulanmasında inme, tekrarlan revaskülarizasyon, ölüm ve miyokart enfarktüsü açısından fark yoktur.

Anahtar Kelimeler

CABG, PCI, mortalite

Kaynakça

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