Evaluation of the Serological, Biochemical and Hemogram Parameters of Patients Prediagnosed with Hydatid Cyst

Yıl 2021, , 414 - 418, 30.09.2021

Cemil Demir , Songül Çetik Yıldız

https://doi.org/10.34087/cbusbed.836958

Öz

Objective: Hydatid cyst or echinococcosis is a zoonotic parasitic disease caused by the larval stages of Echinococcus granulosus, which is common in our country. It is necessary to use radiological and serological methods as diagnosing this disease based on clinical symptoms is very difficult. In this retrospective study, it was aimed to determine the condition in our region by retrospectively analyzing the hemogram, biochemistry, radiological and pathological findings and the epidemiological data of the patients prediagnosed with hydatid cyst.
Materials and Methods: A total of 412 patients, 279 female and 133 male, who applied to various clinics of the Mardin State Hospital with hydatid cyst prediagnosis. 52 patients were diagnosed with hydatid cyst based on ultrasonography, computerized tomography and radiological findings, and liver involvement was detected in all 64 patients, 12 of which were pathologically verified.
Results: 38 (59.3%) of 64 patients included in the study were female, 26 (40.6%) were male and their ages ranged from 0-77. The most common symptoms were severe abdominal pain, distention, chest pain, shortness of breath, cough, fever, nausea and vomiting. 83.4% of the patients applied to the general surgery, 5.5% applied to the pediatric surgery and 10.1% applied to other clinics.
Conclusion: The parameter with the highest increase was GGT, followed by ALT, AST and ALP. Elevated RDW (29%) was the most common finding in the hemogram parameters, followed by decreased MCV, hematocrit and hemoglobin.

Anahtar Kelimeler

Hydatid cyst, echinococcosis, Echinococcus granulosus, diagnosis, epidemiology

Kistik Ekinokokkoz Ön Tanısı ile Başvuran Hastaların Radyolojik, Hemogram ve Biyokimyasal Analizlerinin Değerlendirilmesi

Öz

Giriş ve Amaç: Hydatid cyst ya da echinococcosis, ülkemizde yaygın olarak görülen Echinococcus granulosus’un neden olduğu ve larval dönemin oluşturduğu zoonotik paraziter bir hastalıktır. Klinik semptomlarla bu hastalığın tanısını koymak oldukça zor olduğundan radyolojik ve serolojik yöntemlerin kullanılması gerekmektedir. Bu retrospektif çalışmada, kist hidatik ön tanısı konulan hastaların hemogram, biyokimya, radyolojik, patolojik bulguları ile epidemiyolojik verileri geriye dönük olarak incelenerek bölgemizdeki durumun belirlenip değerlendirilmesi amaçlanmıştır.
Gereç ve Yöntemler: Çalışmaya, Kamu Hastaneler Birliği Mardin Devlet Hastanesine kist hidatik ön tanısı ile çeşitli kliniklere başvuran 279’u kadın 133’ü erkek olmak üzere toplam 412 hasta dahil edilmiştir. 412 hastadan 52’ine ultrasonografi, bilgisayarlı tomografi ve radyolojik bulgular ile kist hidatik tanısı konulmuş olup 12’sinde patolojik olarak doğrulanmış toplam 64 hastanın hepsinde karaciğerde tutulumunun olduğu saptanmıştır.
Bulgular: Çalışmaya alınan 64 hastanın 38 (%59.3)’i kadın, 26 (%40.6)’sı erkek olup yaşları 0 ile 77 arasında değişmektedir. Hastalarda şiddetli karın ağrısı, karın şişliği, göğüs ağrısı, nefes darlığı, öksürük, ateş, bulantı, kusma en sık olarak saptanan semptomlardır. Hastaların sırasıyla; %83.4’ü genel cerrahi, %5.5’inin çocuk cerrahisi ve %10.1’inin ise diğer kliniklerine başvurduğu belirlenmiştir.
Sonuç: Biyokimyasal olarak tanı anında en sık yükselen test GGT olup, bunu ALT, AST, ALP artışı izlemiştir. Hemogram parametrelerinde RDW yüksekliği (%29) en sık rastlanılan bulgu olup, bunu hematokrit, hemoglobin ve MCV düşüklüğü sırayla takip etmiştir.

Anahtar Kelimeler

Kist hidatik, Ekinokokkozis, Echinococcus granulosus, tanı, epidemiyoloji

Kaynakça

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