Does the Presence of Metabolic Syndrome Alter Serum Uric Acid Concentrations, Pain, and Well-Being in Patient with Chronic Musculoskeletal Pain?

Year 2022, Volume: 12 Issue: 4, 793 - 798, 30.12.2022

Şeyda Toprak Çelenay , Derya Özer Kaya , Senem Şaş

https://doi.org/10.33808/clinexphealthsci.832112

Abstract

Objective: To compare serum uric acid concentrations, pain and well-being in patients having chronic musculoskeletal pain with and without MetS, and investigate cut-off values.
Methods: Patients having chronic musculoskeletal pain with (MetS group, n=48) and without MetS (control group, n=52) were included. The serum uric acid concentration, pain intensity, body composition, physical activity level, quality of life, and psychological status were evaluated by a uric acid blood test, Visual Analogue Scale, Bio-impedance Analyzer, International Physical Activity Questionnaire-7 (IPAQ-7), Nottingham Health Profile, and Hospital Anxiety and Depression Scale, respectively.
Results: Uric acid level, fat mass, waist/hip ratio were found higher in the MetS group in comparison to the control group (P<0.05). It was seen that patients in the MetS group had lower physical activity levels than those in the control group (P<0.05). The cut-off points of the uric acid level, fat mass, waist/hip ratio, and physical activity level for detecting MetS were found as 5.25 mg/dl, 37.50 kg, 0.91, and 247.25 METsminutes/week, respectively.
Conclusion: Patients with MetS had a greater uric acid level, fat mass, waist/hip ratio, and a lower physical activity level than those without MetS. The increase of uric acid level, fat mass, and waist/hip ratio, and the decrease of physical activity may be critical for patients having musculoskeletal pain with MetS. These results should be considered for the management of these patients.

Keywords

Metabolic syndrome, pain, uric acid, body composition, quality of life

Supporting Institution

yok

Project Number

yok

Thanks

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