Comparison of efficacy of intraarticular polyacrylamide hydrogel and methylprednisolone acetate in patients with knee osteoarthritis

Yıl 2018, Cilt: 43 Sayı: Ek 1, 124 - 128, 29.12.2018

Ahmet Issın , Nizamettin Koçkara , İsmet Yalkın Çamurcu

https://doi.org/10.17826/cumj.403372

Öz

Purpose: The aim of this study was to compare and evaluate the efficacy of intraarticular methylprednisolone acetate and an intra-articular polyacrylamide hydrogel in patients with different stages of knee osteoarthritis. 

Materials and Methods: Patients with symptomatic knee osteoarthritis and history of failed pharmacotherapy or physiotherapy interventions were included in this study. The first 64 consecutive patients got intra-articular polyacrylamide hydrogel, the latter 79 consecutive patients got intra-articular methylprednisolone acetate. Patients were evaluated by WOMAC score and self-assessment questions. 

Results: There was no statistically significance difference between groups when WOMAC scores and answers of self-assessment questions were compared. 

Conclusion: Intra-articular use of polyacrylamide hydrogel was not superior to methylprednisolone acetate, for patients with knee osteoarthritis. 

Anahtar Kelimeler

gonarthrosis, osteoarthritis, methylprednisolone acetate, injection, viscosupplementation

Diz osteoartriti olan hastalarda eklem içi poliakrilamid hidrojel ve metilprednizolon asetatın etkinliğinin karşılaştırılması

Öz

Amaç: Bu çalışmanın amacı, farklı evrelerde diz osteoartriti olan hastalarda eklem içi metilprednizolon asetat ve eklem içi poliakrilamid hidrojelin etkinliğini karşılaştırmak ve değerlendirmektir.

Gereç ve Yöntem: Semptomatik diz osteoartriti olan ilaç veya fizik tedaviden fayda görmemiş hastalar çalışmaya dahil edildi. İlk 64 hasta eklem içi poliakrilamid hidrojel tedavisi aldı, sonraki 79 hasta ise eklem içi metilprednizolon asetat tedavisi aldı. Hastalar WOMAC skoru ve özdeğerlendirme soruları ile değerlendirildi. 

Bulgular: WOMAC skorları ve özdeğerlendirme sorularının cevapları karşılaştırıldığında gruplar arasında istatistiksel olarak anlamlı bir fark yoktu.

Sonuç: Diz osteoartriti olan hastalarda, eklem içi poliakrilamid hidrojelin kullanımı metilprednizolon asetata göre üstün değildir.

Anahtar Kelimeler

gonarthrosis, osteoarthritis, methylprednosone acetate, methylprednisone acetate, injection, viscosupplementation

Kaynakça

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