RETINAL NERVE FIBER LAYER ANALYSIS IN OBSTRUCTIVE SLEEP APNEA

Yıl 2018, Cilt: 32 Sayı: 1, 33 - 39, 18.05.2018

Rukiye Aydın , Funda Dikkaya Rengin Yıldırım

https://doi.org/10.5505/deutfd.2017.87487

Öz

Objective:
To investigate the retinal nerve fiber thickness
(RNFL) in patients with Obstructive sleep apnea syndrome (OSAS) and to
determine the correlation of ocular changes with the severity of disease.

Material
and Methods: 21 patients with Respiratory Disturbance Index (RDI)
between 5-29 were included in group 1 and 33 patients with RDI > 29 in
group 2. Patients received RNFL measurement with optical coherence tomography
(OCT). The difference between the groups and the correlation of RFNL with RDI,
mean and minimum O₂ saturation was evaluated.

Results: The
mean RNFL was 117.33±7.57 in group 1, 111.91 ±8.64 μm in group2. There was
statistically significant difference (p=0.023). RNFL in inferior quadrant was
147.95 ±12.97 for group 1, 137.27±17.94 μm for group 2. The difference was
statistically significant (p=0.032). Mean RNFL was correlated with RDI.

Conclusion: There is a significant decreare in RFNL occur in
patients with OSAS and changes show correlation with severity of disease.
Awareness of relationship helps ophthalmologists to question their patients in
terms of OSAS symptoms.

Anahtar Kelimeler

Obstructive Sleep Apnea Syndrome, Optical Coherence Tomography, Retinal Nerve Fiber Thickness

Obstrüktif uyku apne sendromunda retina sinir lifi analizi

Öz

Amaç: Obstrüktif uyku apne sendromu
(OUAS) hastalarını retina sinir lifi tabakası (RSLT) kalınlıkları yönünden
incelemek ve oküler değişikliklerin hastalığın şiddeti ile ilişkisini
belirlemek.

Gereç ve Yöntem: OUAS tanılı 54 hasta göz bulguları açısından
değerlendirildi. Respiratory Disturbance Index-Anormal Solunum Olayı İndeksi (RDI) 5-29
olan 21’i grup 1, RDI>29 olan 33’ü ise grup 2 kapsamında
sınıflandırıldı. Hastalara Optik Koherens
Tomografi (OKT) ile RSLT
ölçümleri yapıldı. Gruplar elde edilen veriler açısından karşılaştırılırken,
verilerin RDI, ortalama ve minimum O₂ satürasyonu ile olan
ilişkileri de incelendi.

Bulgular: Ortalama RSLT grup 1’de 117,33±7,57 μm, grup 2’de ise 111,91
±8,64 μm olarak ölçüldü.  RSLT’deki
incelme istatistiksel olarak anlamlı bulundu (p=0,023). İnferior RSLT grup 1’de
147,95 ±12,97 μm, grup 2’de 137,27±17,94 μm olarak bulundu. Grup 2’deki incelme
istatistiksel olarak anlamlı bulundu (p=0,032). Ortalama RSLT ile RDI arasında
negatif korelasyon saptandı .

Sonuç:
OUAS hastalarında RSLT kalınlığında azalma meydana gelmekte ve bu
değişimler OUAS’ın ağırlığı ile korelasyon göstermektedir. Bu iki durum
arasındaki ilişkinin bilinmesi hastaların öncelikle göz hekimi tarafından
görüldüklerinde olası OUAS semptomları yönünden sorgulanmalarına olanak
sağlayacaktır.

Anahtar Kelimeler

Obstrüktif Uyku Apne Sendromu, Optik Kohorens Tomografi, Retina Sinir Lifi Kalınlığı

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