Klinik Araştırma
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Pankreatikoduodenektomi Deneyimlerimiz: Tek Merkez 5 Yıllık Sonuçların Analizi

Yıl 2021, Cilt: 4 Sayı: 1, 53 - 57, 08.06.2021

Öz

Özet
Amaç: Çalışmamızın amacı son 5 yıl içinde kliniğimizde yapılan pankreatikoduodenektomi(PD) vakalarının verilerini çıkararak bunlar arasındaki korelasyonu, preoperatif ve postoperatif surveye etki eden parametreleri değerlendirmekti.
Materyal Metot: Bu çalışmada Necmettin Erbakan Üniversitesi Meram Tıp Fakültesi Genel Cerrahi Kliniği’nde 2014 ve 2019 yılları içerisinde çeşitli nedenlerle yapılmış olan pankreatikoduodenektomi vakalarını içermektedir. Çalışmada hastaların yaşı, cinsiyeti, preoperatif albumin, Ca 19.9 ve total bilirubin değerleri, ameliyatta elde edilen patolojik preparatta histolojik grade, lenfovasküler invazyon ve tümör boyutu değerlendirildi.
Bulgular: Ca 19.9, lenfovasküler invazyon, tümör boyutu ve histolojik grade sağ kalımı olumsuz etkileyen prognostik faktörler olarak değerlendirildi.
Sonuç: preoperatif ölçülen Ca 19.9 prognostik açıdan önemlidir. Pankreatikoduodenektomi yapılacak olan hastaların seçiminde CA 19.9 kullanılabilir ve sağ kalımları hakkında bilgi edinilebilir.

Kaynakça

  • 1.Noor MT, Vaiphei K, Nagi B, Singh K, Kochnar R. Role of needle knife assisted ampullar ybiopsy in the diagnosis of periampullary carcinoma. World J GastrointestEndosc. 2011;3:220–224.
  • 2. Kim CG, Jo S, Kim JS. Impact of surgical volume on nation wide hospital mortality after pancreaticoduodenectomy. World J Gastroenterol. 2012;18:4175-4181.
  • 3. Beger HG, Rau B, Gansauge F, Poch B, Link KH. Treatment of pancreatic cancer: Challenge of the facts. World J Surg. 2003;27:1075-1084.
  • 4. Jarufe NP, Coldham C, Mayer AD, Mirza DF, Buckels JA, Bramhall SR. Favourable prognostic factors in a large UK experience of adenocarcinoma of the head of the pancreas and periampullary region. DigSurg. 2004;21:202–209.
  • 5. Cameron JL, He J. Two thousand consecutive pancreaticoduodenectomies. J AmCollSurg. 2015;220:530-6
  • 6. Cameron JL, Riall TS, Coleman J, Belcher KA. One thousand consecutive pancreaticoduodenectomies. AnnSurg. 2006;244:10-5
  • 7. Şeren TD, Topgül K, Koca B, Erzurumlu K. Factors affecting survival in patients who underwent pancreaticoduodenectomy for periampullary cancers.
  • 8. El Nakeeb A, El Shoraby M, El Dosoky M, Nabeh A, El Sorogy M. Prognostic factors affecting survival after pancreaticoduodenectomy for pancreatic adenocarcinoma (single center experience).
  • 9. Hatzaras I, George N, Muscarella P, Melvin S,Ellison C, Bloomston M. Predictors of Survival in Periampullary Cancers Following Pancreaticoduodenectomy. AnnSurgOncol. 2010 Apr; 17(4): 991–997.
  • 10. Di Martino M, Ielpo B, de Nova JLM, Muñoz EA, Santamaria C et al. Lymph Node Ratio, Perineural Invasion and R1 Resection as Independent Prognostic Factors in Pancreatic Adenocarcinoma: A Retrospective Cohort Study. SurgTechnolInt. 2020 Mar 18;36. pii: sti36/1239.
  • 11.Morimoto M, Honjo S, Sakamoto T, Yagyu T, Uchinaka et al. PrognosticImpact of Pre- and Post-operative P-CRP Levels in PancreaticCancerPatients. YonagoActaMed. 2020 Feb; 63(1): 70–78.
  • 12. Jia F, Liu M, Li X, Zhang F, Yue S. et al. Relationship between S100A4 protein expression and pre-operative serum CA19.9 levels in pancreatic carcinoma and its prognostic significance. World J SurgOncol. 2019; 17: 163.

Our Pancreaticoduodenectomy experiences: Analysis of Single Center Results for Five Years

Yıl 2021, Cilt: 4 Sayı: 1, 53 - 57, 08.06.2021

Öz

Kaynakça

  • 1.Noor MT, Vaiphei K, Nagi B, Singh K, Kochnar R. Role of needle knife assisted ampullar ybiopsy in the diagnosis of periampullary carcinoma. World J GastrointestEndosc. 2011;3:220–224.
  • 2. Kim CG, Jo S, Kim JS. Impact of surgical volume on nation wide hospital mortality after pancreaticoduodenectomy. World J Gastroenterol. 2012;18:4175-4181.
  • 3. Beger HG, Rau B, Gansauge F, Poch B, Link KH. Treatment of pancreatic cancer: Challenge of the facts. World J Surg. 2003;27:1075-1084.
  • 4. Jarufe NP, Coldham C, Mayer AD, Mirza DF, Buckels JA, Bramhall SR. Favourable prognostic factors in a large UK experience of adenocarcinoma of the head of the pancreas and periampullary region. DigSurg. 2004;21:202–209.
  • 5. Cameron JL, He J. Two thousand consecutive pancreaticoduodenectomies. J AmCollSurg. 2015;220:530-6
  • 6. Cameron JL, Riall TS, Coleman J, Belcher KA. One thousand consecutive pancreaticoduodenectomies. AnnSurg. 2006;244:10-5
  • 7. Şeren TD, Topgül K, Koca B, Erzurumlu K. Factors affecting survival in patients who underwent pancreaticoduodenectomy for periampullary cancers.
  • 8. El Nakeeb A, El Shoraby M, El Dosoky M, Nabeh A, El Sorogy M. Prognostic factors affecting survival after pancreaticoduodenectomy for pancreatic adenocarcinoma (single center experience).
  • 9. Hatzaras I, George N, Muscarella P, Melvin S,Ellison C, Bloomston M. Predictors of Survival in Periampullary Cancers Following Pancreaticoduodenectomy. AnnSurgOncol. 2010 Apr; 17(4): 991–997.
  • 10. Di Martino M, Ielpo B, de Nova JLM, Muñoz EA, Santamaria C et al. Lymph Node Ratio, Perineural Invasion and R1 Resection as Independent Prognostic Factors in Pancreatic Adenocarcinoma: A Retrospective Cohort Study. SurgTechnolInt. 2020 Mar 18;36. pii: sti36/1239.
  • 11.Morimoto M, Honjo S, Sakamoto T, Yagyu T, Uchinaka et al. PrognosticImpact of Pre- and Post-operative P-CRP Levels in PancreaticCancerPatients. YonagoActaMed. 2020 Feb; 63(1): 70–78.
  • 12. Jia F, Liu M, Li X, Zhang F, Yue S. et al. Relationship between S100A4 protein expression and pre-operative serum CA19.9 levels in pancreatic carcinoma and its prognostic significance. World J SurgOncol. 2019; 17: 163.
Toplam 12 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Klinik Tıp Bilimleri
Bölüm Makaleler
Yazarlar

Mehmet Aykut Yıldırım 0000-0001-9580-6004

Ömer Kişi Bu kişi benim

Yayımlanma Tarihi 8 Haziran 2021
Yayımlandığı Sayı Yıl 2021 Cilt: 4 Sayı: 1

Kaynak Göster

APA Yıldırım, M. A., & Kişi, Ö. (2021). Our Pancreaticoduodenectomy experiences: Analysis of Single Center Results for Five Years. Dünya Sağlık Ve Tabiat Bilimleri Dergisi, 4(1), 53-57.