Retrospective Analysis of Tetrathyridiosis Cases in Cats and Dogs in Hatay Province Between 2015 and 2022

Yıl 2024, Cilt: 17 Sayı: 1, 26 - 30, 30.06.2024

Aykut Zerek , İpek Erdem , Meral Aydenizöz , Mustafa Karagöz , Mehmet Yaman

Öz

Peritoneal tetrathyridiosis is a rare parasitic disease that occurs accidentally in various operations or necropsies due to its usually asymptomatic course in cats and dogs. However, tetrathyridium can cause chronic peritonitis with ascites and even fatal consequences in cats and dogs, sometimes. In this study, the prevalence of tetrathyridiosis cases was investigated in 897 cats and 12 057 dogs brought to Hatay Metropolitan Municipality Stray Animal Care and Rehabilitation Center for ovariohysterectomy and orchiectomy between 2015 and 2022. Small, white larval-like structures found in the peritoneum, mesenterium and omentum parts of the animals were placed in vials containing a 10% formalin solution. They were then transferred to the Laboratory of the Department of Parasitology of the Faculty of Veterinary Medicine of Hatay Mustafa Kemal University for examination. As a result of the parasitological examination, it was determined that these small structures were tetrathyridium, the second-stage larva of Mesocestoides spp. Tetrathyridium was found in 4 of 897 cats (4♀) (0.44%), 17 of 12 057 dogs (15♀, 2♂) (0.14%) and 21 of a total of 12 954 animals (19♀, 2♂) (0.16%) during the ovariohysterectomy and orchiectomy operations. This retrospective study investigating the presence of tetrathyridium in cats and dogs in Hatay province is the first study in Türkiye.

Anahtar Kelimeler

Cat, dog, peritoneal tetrathyridiosis

Hatay İlinde Kedi ve Köpeklerde 2015-2022 Yılları Arasında Tetrathyridiosis Olgularının Retrospektif Analizi

Öz

Peritoneal tetrathyridiosis kedi ve köpeklerde genellikle asemptomatik seyretmesi nedeniyle çeşitli operasyonlarda veya nekropsilerde tesadüfen rastlanan ve nadir görülen paraziter bir hastalıktır. Ancak tetrathyridiumlar kedi ve köpeklerde, bazen kronik asitesli peritonitise ve hatta ölümcül sonuçlara neden olabilirler. Bu çalışmada, 2015-2022 yılları arasında ovariohisterektomi ve orşiektomi amacıyla Hatay Büyükşehir Belediyesi Sahipsiz Hayvan Bakım ve Rehabilitasyon Merkezi'ne getirilen 897 kedi ve 12 057 köpekte tetrathyridiosis olgularının prevalansı araştırıldı. Hayvanların periton, mezenterium ve omentum kısımlarında rastlanan küçük, beyaz renkli larva benzeri yapılar %10’luk formalin çözeltisi içeren şişelere konuldu. Daha sonra incelenmek üzere Hatay Mustafa Kemal Üniversitesi Veteriner Fakültesi Parazitoloji Ana Bilim Dalı Laboratuvarı’na nakledildi. Yapılan parazitolojik muayene sonucunda bu yapıların Mesocestoides spp.’nin ikinci dönem larvası tetrathyridium oldukları tespit edildi. Ovariohisterektomi ve orşiektomi operasyonları esnasında 897 kedinin 4’ünde (4♀) (%0.44), 12 057 köpeğin 17’sinde (15♀, 2♂) (%0.14) toplamda da 12 954 hayvanın 21’inde (19♀, 2♂) (%0.16) tetrathyridiumlara rastlandı. Hatay ilinde kedi ve köpeklerde tetrathyridium varlığının araştırıldığı bu retrospektif çalışma, Türkiye’de ilk çalışma olma niteliğindedir.

Anahtar Kelimeler

Kedi, köpek, peritoneal tetrathyridiosis

Kaynakça

• 1Skirnisson K, Jouet D, Ferté H, Nielsen ÓK. (2016). Occurrence of Mesocestoides canislagopodis (Rudolphi, 1810) (Krabbe, 1865) in Mammals and Birds in Iceland and its Molecular Discrimination within the Mesocestoides Species Complex. Parasitol Res. 115: 2597–2607.
• James H. (1968). Studies on the Genus Mesocestoides (Cestoda: Cyclophyllidea). Iowa State University, Ames, IA.
• Loos-Frank B. (1991). One or Two Intermediate Hosts in the Life Cycle of Mesocestoides (Cyclophyllidea, Mesocestoididae)? Parasitol. Res. 77: 726–728.
• Padgett KA, Boyce WM. (2004). Life-History Studies on Two Molecular Strains of Mesocestoides (Cestoda:Mesocestoididae): Identification of Sylvatic Hosts and Infectivity of Immature Life Stages. J. Parasitol. 90: 108–113.
• Fuentes MV, Galan-Puchades MT, Malone JB. (2003). Short report - A New Case Report of Human Mesocestoides Infection in the United States. Am. J. Trop. Med. Hyg. 68: 566–567.
• Sz´ell Z, Tolnai Z, Sr´eter T. (2015). Environmental Determinants of the Spatial Distribution of Mesocestoides spp. and Sensitivity of Flotation Method for the Diagnosis of Mesocestoidosis. Vet. Parasitol. 212: 427–430.
• Papini R, Matteini A, Bandinelli P, Pampurini F, Mancianti F. (2010). Effectiveness of Praziquantel for Treatment of Peritoneal Larval Cestodiasis in Dogs: A Case Report. Vet Parasitol 170:158–161.
• McAllister CT, Conn DB, Freed PS, Burdick DA. (1991). A New Host and Locality Record for Mesocestoides sp. Tetrathyridia (Cestoidea:Cyclophyllidea), With A Summary of the Genus From Snakes of the World. J Parasitol 77:329–331.
• Literák I, Olson PD, Georgiev BB, Špakulová M. (2004). First Record of Metacestodes of Mesocestoides spp. in the Common Starling (Sturnus vulgaris) in Europe, with an 18S rDNA Characterization of the Isolate. Folia Parasitol. 51:45–49.
• Carta S, Corda A, Tamponi C, Dessì G, Nonnis F, Tilocca L, Cotza A, Knoll S, Varcasia A, Scala A. (2021). Clinical Forms of Peritoneal Larval Cestodiasis by Mesocestoides spp. in Dogs: Diagnosis, Treatment and Long Term Follow-Up. Parasitol Res. 120: 1727-1735.
• Crosbie PR, Nadler SA, Platzer EG, Kerner C, Mariaux J, Boyce WM. (2000). Molecular Systematics of Mesocestoides spp. (Cestoda:Mesocestoididae) from Domestic Dogs (Canis familiaris) and Coyotes (Canis latrans). J Parasitol 86:350–357.
• Georgiev BB, Kornyushin VV. (1994). Family Paruterinidae Fuhrmann, 1907 (senus lato). In: Keys to the Cestode Parasites of Vertebrates. Khalil LF, Jones A, Bray RA (eds). pp 559–584. CAB International, Wallingford.
• Hrckova G, Miterpakova M, O’Connor A, Snabel V, Olson PD. (2011). Molecular and Morphological Circumscription of Mesocestoides Tapeworms from Red Foxes (Vulpes vulpes) in Central Europe. Parasitology 138:638–647.
• Zaleśny G, Hildebrand J. (2012). Molecular Identification of Mesocestoides spp. from Intermediate Hosts (Rodents) in Central Europe (Poland). Parasitol Res. 110:1055–1061.
• Nickisch-RosenegkM, Richard L, Loos-Frank B. (1999). Contributions to the Phylogeny of the Cyclophyllidea (Cestoda) Inferred from Mitochondrial 12S rDNA. J Mol Evol 48:586–596.
• Padgett KA, Boyce WM. (2005). Ants as First Intermediate Hosts of Mesocestoides on San Miguel Island, USA. J Helminthol. 79:67–73.
• Literák I, Tenora F, Letkova V, Goldova M, Torres J, Olson PD. (2006). Mesocestoides litteratus (Batsch, 1786) (Cestoda:Cyclophyllidea:Mesocestoididae) from the Red Fox: Morphological and 18S rDNA Characterization of European Isolates. Helminthologia. 43:191–195.
• Di Filippo MM, Meoli R, Cavallero S, Eleni C, De Liberato C, Berrilli F. (2018). Molecular Identification of Mesocestoides sp. Metacestodes in a Captive Gold-Handed Tamarin (Saguinus midas). Infect Genet Evol. 65:399–405.
• Varcasia A, Sanna D, Casu M, ve ark. (2018). Species Delimitation Based on mtDNA Genes Suggests the Occurrence of New Species of Mesocestoides in the Mediterranean Region. Parasit Vectors. 11(1): 619.
• Berrilli E, Simbula G. (2020). First Molecular Identification of the Tapeworm Mesocestoides litteratus from an Italian wall lizard (Podarcis siculus). Infect Genet Evol. 81:104233.
• McGarry J, Collins M, Baross K. (2020). UK Report of Tapeworm. Vet. Rec. 186: 498–499.
• Conn DB. (1990). The Rarity of Asexual Reproduction Among Mesocestoides Tetrathyridia (Cestoda). J. Parasitol. 76: 453–455.
• Siles-Lucas M, Hemphill A. (2002). Cestode Parasites: Application of in Vivo and in Vitro Models for Studies on the Host-Parasite Relationship. Adv. Parasitol. 51: 133–230.
• Heneberg P, Georgiev BB, Sitko J, Liter´ak I. (2019). Massive Infection of a Song Thrush by Mesocestoides sp. (Cestoda) Tetrathyridia that Genetically Match Acephalic Metacestodes Causing Lethal Peritoneal Larval Cestodiasis in Domesticated Mammals. Parasit Vectors. 12: 230.
• Crosbie PR, Boyce WM, Platzer EG, Nadler SA, Kerner C. (1998). Diagnostic Procedures and Treatment of Eleven Dogs with Peritoneal Infections Caused by Mesocestoides spp. J Am Vet Med Assoc. 213: 1578–1583.
• Boyce W, Shender L, Schultz L, Vickers W, Johnson C, Ziccardi M, Beckett L, Padgett K, Crosbie P, Sykes J. (2011). Survival Analysis of Dogs Diagnosed with Canine Peritoneal Larval Cestodiasis (Mesocestoides spp.). Vet Parasitol. 180:256–261.
• Haziroglu R, Ozgencil E, Guvenc T, ve ark. (2005). Peritoneal Tetrathyridiosis in a Siamese Cat–A Case Report. Vet Arh. 75: 453-458.
• Avci H, Toplu N. (2012). Tetrathyridiosis and Tubulopapillary Carcinoma Occurring Simultaneously in the Mammary Gland of a Cat. Reprod domest anim. 47(3): e36-e38.
• Aldemir OS, Erdoğan G. (2014). A Rare Case of Peritoneal Larval Cestodiosis by Mesocestoides from Aydın Region in Turkey. Turkish JAF Sci Tech. 2(5): 249-250.
• Gulcubuk A, Erdogan O, Ozturk GY, ve ark. (2015). Case Report: Intratesticular Tetrathyridiosis in a Cat. Rev Méd Vét. 166(3/4): 72-75.
• Zerek A, Erdem İ, Karagöz M, Yaman M, Aydenizöz M. (2022). A Case of Mesenterial Tetrathyridiosis in a Cat. 11th International Medicine and Health Sciences Researches Congress (UTSAK), 24-25 December, Ankara-Türkiye.
• Toplu N, Yildiz K, Tunay R. (2004). Massive Cystic Tetrathyridiosis in a Dog. J Small Anim Pract. 45:410–412.
• Yildiz K, Tong S. (2011). Canine Peritoneal Larval Cestodosis in a Dog. Tierärztl Prax Ausg K: Kleintiere Heimtiere, 39(06): 448-450.
• Aypak S, Aysul N, Ural K, ve ark. (2012). A Case of Diffuse Peritoneal Larval Mesocestoides corti (syn. M. vogae) Cestodiasis in a Dog in Turkey. Kafkas Univ Vet Fak Derg. 18(5):885–888.
• Selver MM, Beyazit A. (2013). İzmir’de Bir Köpekte Mezenterial Larval Cestodiosis Olgusu. Turkiye Parazitol Derg. 37: 292-4.
• Altaş MG. (1991). Elazığ İli Kırsal Yöre Kedilerinde Ekto ve Endoparazitler ve Bunların Halk Sağlığı Yönünden Önemi. FÜ Sağ Bil Derg. 13: 233-42.
• Yaman M, Ayaz E, Gül A, Muz MN. (2006). Hatay İlinde Bakısı Yapılan Kedi ve Köpeklerde Helmint Enfeksiyonları. Turkiye Parazitol Derg. 30 (3): 200-204.
• Eleni C, Scaramozzino P, Busi M, Ingrosso S, D’amelio S, De Liberato C. (2007). Proliferative Peritoneal and Pleural Cestodiasis in a Cat Caused by Metacestodes of Mesocestoides sp. Anatomohistopathological Findings and Genetic Identification. Parasite 14:71–76.
• Rausch RL. (1994). Family Mesocestoididae Fuhrmann, 1907. In: Keys to the Cestode Parasites of Vertebrates. Khalil LF, Jones A, Bray RA (eds). pp: 309-314. CAB International, Wallingford, UK.
• Barutzki D, Schaper R. (2011). Results of Parasitological Examinations of Faecal Samples from Cats and Dogs in Germany between 2003 and 2010. Parasitol Res. 109: 45-60.
• Ziam H, Kelanemer R, Belala R, ve ark. (2022). Prevalence and Risk Factors Associated with Gastrointestinal Parasites of Pet Dogs in North-Central Algeria. Comp Immunol Microbiol Infect Dis. 86: 101817.
• Nagamori Y, Payton ME, Looper E, Apple H, Johnson EM. (2020). Retrospective Survey of Parasitism Identified in Feces of Client-Owned Cats in North America from 2007 Through 2018. Vet Parasitol. 277: 109008.
• Silva YHD, Campos DR, Lima GAC, et al. (2023). Prevalence of Gastrointestinal Parasites in Domestic Cats (Felis catus) Diagnosed by Different Coproparasitological Techniques in the Municipality of Seropédica, Rio de Janeiro. Rev Bras Parasitol Vet. 32(3): e006223.
• Riggio F, Mannella R, Ariti G, Perrucci S. (2013). Intestinal and Lung Parasites in Owned Dogs and Cats from Central Italy. Vet Parasitol. 193(1-3): 78-84.
• Kırman R, Akyüz M, Balkaya İ, Güven E, Avcıoğlu H. (2023). Gastrointestinal Helminths of Stray Dogs in Erzurum province: Prevalence and Risk to Public Health. Ankara Üniv Vet Fak Derg. 1-4.
• Wierzbowska IA, Kornaś S, Piontek AM, Rola K. (2020). The Prevalence of Endoparasites of Free Ranging Cats (Felis catus) from Urban Habitats in Southern Poland. Animals. 10(4): 748.
• Calvete C, Lucientes J, Castillo JA, et al. (1998). Gastrointestinal Helminth Parasites in Stray Cats from the Mid-Ebro Valley, Spain. Vet Parasitol. 75(2–3):235–240.
• Arbabi M, Hooshyar H. (2009). Gastrointestinal Parasites of Stray Cats in Kashan, Iran. Trop Biomed. 26(1):16–22.
• Borji H, Razmi G, Ahmadi A, Karami H, Yaghfoori S, Abedi V. (2011). A Survey on Endoparasites and Ectoparasites of Stray Cats from Mashhad (Iran) and Association with Risk Factors. J Parasit Dis. 35(2):202–206.
• Hajipour N, Imani Baran A, Yakhchali M, et al. (2016). A Survey Study on Gastrointestinal Parasites of Stray Cats in Azarshahr,(East Azerbaijan province, Iran). J Parasit Dis. 40: 1255-1260.
• Öter K, Bilgin Z, Tinar R, Tuzer E. (2011). Tapeworm Infections in Stray Dogs and Cats in İstanbul, Turkey. Kafkas Üniv Vet Fak Derg. 17 (4): 595-599.
• Chelladurai JRJ, Brewer MT. (2021). Global Prevalence of Mesocestoides Infections in Animals–A systematic Review and Meta-Analysis. Vet Parasitol. 298: 109537.
• Venco L, Kramer L, Pagliaro L, Genchi C. (2005). Ultrasonographic Features of Peritoneal Cestodiasis Caused by Mesocestoides sp. in a Dog and in a Cat. Vet Radiol Ultrasound. 46(5): 417-422.
• Lanteri G, Di Caro G, Capucchio MT, et al. (2017). Mesocestoidosis and Multivisceral Tetrathyridiosis in a European Cat. Vet Med. 62 (6): 356-362.
• Petrescu VF, Morganti G, Moretti G, et al. (2020). Severe Pleural Effusion in a Dog Affected by Larval Mesocestodiasis. Top Companion Anim Med. 40: 100450.
• Zeman DH, Cheney JM, Waldrup KA. (1988). Scrotal Cestodiasis in a Dog. Cornell Vet. 78:273–9.
• Caruso KJ, James MP, Fisher D, Paulson RL, Christopher MM. (2003). Cytologic Diagnosis of Peritoneal Cestodiasis in Dogs Caused by Mesocestoides sp. Vet Clin Pathol. 32(2): 50-60.
• Barsanti JA, Jones BD, Bailey WS, Knipling GD. (1979). Diagnosis and Treatment of Peritonitis Caused by a Larval Cestode Mesocestoides spp. in a Dog. Cornell Vet. 69:45–53.
• Williams JF, Lindsay M, Engelkirk P. (1985). Peritoneal Cestodiasis in a Dog. J Am Vet Med Assoc. 186:1103–5.
• Rodriguez F, Herraez P, de los Monteros AE, Ramirez GA, Jover A, Lorenzo H. (2003). Testicular Necrosis Caused by Mesocestoides Species in a Dog. Vet Rec. 153: 275-276.
• Kashiide T, Matsumoto J, Yamaya Y, ve ark. (2014). Case Report: First Confirmed Case of Canine Peritoneal Larval Cestodiasis Caused by Mesocestoides vogae (syn. M. corti) in Japan. Vet Parasitol. 201: 154-157.
• Wirtherle N, Wiemann A, Ottenjann M, Linzmann H, van der Grinten E, Kohn B, Gruber A.D., Clausen P.-H. (2007). First Case of Canine Peritoneal Larval Cestodosis Caused by Mesocestoides lineatus in Germany. Parasitol Int. 56:317–320.
• Dahlem D, Bangoura B, Ludewig E, et al. (2015). Tetrathyridiosis in a Domestic Shorthair Cat. J Feline Med Surg Open Rep. 1-6.