Stevens Johnson Syndrome Like Skin Lesions in a Patient With Systemic Lupus Erythematosus After Hydroxychloroquine Treatment, a Case

Yıl 2020, Cilt: 1 Sayı: 2, 60 - 65, 29.09.2020

Orhan Zengin , Mustafa Erkut Önder , Abdi İbrahim Sönmez , İbrahim Halil Türkbeyler

Öz

Abstract
Stevens Johnson Syndrome (SJS) is a clinical syndrome with a high morbidity and mortality, characterized by exfoliation of the skin, generally due to medications, and less frequently due to infections. Most frequently sulphonamides, penicillin, and anti-convulsants were among blamed medications. Systemic lupus erythematosus (SLE) is a systemic auto-immune disorder and skin involvement is frequently seen. Hydroxychloroquine (HCQ) is an important agent which is used in the treatment of SLE and which increases survival. Its side effects include skin reactions. We present here a case of SJS like skin lesions in an 38-years-old female patient with SLE after receiving HCQ.
Özet
Stevens Johnson Sendromu (SJS), genellikle ilaçlara bağlı olarak ve daha az sıklıkla enfeksiyonlara bağlı olarak cildin dökülmesi ile karakterize, yüksek morbidite ve mortaliteye sahip klinik bir sendromdur. En sık suçlanan ilaçlar sülfonamidler, penisilin ve anti-konvülzanlardır. Sistemik lupus eritematozus (SLE), sistemik bir otoimmün bozukluktur ve cilt tutulumu sıklıkla görülür. Hidroksiklorokin (HCQ), SLE tedavisinde kullanılan ve sağkalımı artıran önemli bir ajandır. Yan etkileri cilt reaksiyonlarını içerir. Burada, HCQ aldıktan sonra SLE'li 38 yaşında bir kadın hastada SJS benzeri deri lezyonları olgusunu sunuyoruz.

Anahtar Kelimeler

Stevens Johnson Sydrome, hydroxychloroquine, lupus

Kaynakça

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