THE DIAGNOSTIC VALUE OF IMMATURE GRANULOCYTE PERCENTAGE IN ACUTE APPENDICITIS PATIENTS.

Yıl 2022, Cilt: 3 Sayı: 2, 354 - 364, 22.08.2022

Giray Altunok Ersin Altınsoy

Öz

Studies have suggested that immature granulocyte percentage (IG%) levels may be an early marker of inflammation. In this study, it was tried to investigate whether there is a diagnostic value of IG% in appendicitis patients.
This study was conducted retrospectively between the dates of 01.01.2018 and 01.05.2019 at Mersin University Faculty of Medicine, Department of Emergency Medicine. Patients over 18 years of age who were admitted to the emergency department and operated with the diagnosis of acute appendicitis were included in the study. The patients were classified into three groups as normal (control group), simple and complicated appendicitis.
A total of 353 patients with a pre-diagnosis of appendicitis, 194 (55%) male, were included in the study. The mean age of the patients was calculated as 35.1 ± 14.0. The leukocyte parameter was found to be significant in distinguishing the disease; It was determined that the values of the patient group were higher than the values of the control group. (p values, respectively; 0.022 and 0.038). For CRP parameter; those with inflamed appendix were found to be lower than those with perforated appendicitis (p <0.001). When the neutrophil percentage parameter is examined; it was determined that patients with perforated appendicitis were higher than those with inflamed appendicitis (p <0.001). The immature granulocyte percentage (IG%) was found to have low power to distinguish disease and complications. For immature granulocyte percentage (IG%); AUC (Area under curve) was 0.505 and cut value was 0.2 while p value was 0.9128 in differentiating the disease. In distinguishing complications; AUC was 0.649 and cut value was 0.4 while p value was 0.0510.
In our study, it was found that immature granulocyte percentage was statistically insignificant in distinguishing disease and complication. It was determined that the leukocyte value was significant in distinguishing the disease, and the CRP and percentage of neutrophils were statistically significant in distinguishing complications.

Anahtar Kelimeler

Appendicitis,, Complicated appendicitis,, C-reactive protein,, White blood cell,, immature granulocyte percentage,, Neutrophil percentage,

Kaynakça

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