Epidemiological features of the lip cancers and it’s relation with smoking

Yıl 2013, Cilt: 18 Sayı: 2, 64 - 67, 03.07.2013

Hakan Çankaya Mehmet Fatih Garça , Nazım Bozan Dağhan Işık Ahmet Faruk Kıroğlu

Öz

Abstract. To evaluate the epidemiological features of thepatients with lip cancer and the relationship between these features andsmoking. The relationship between epidemiological features, localization of thelesions, histopathological type and smoking was evaluated in 92 patients inthis study. The number of the patients with lip cancers was average 5.41 peryear and the 80% of the cases were male. The average age was 62.1. When theaverage age was compared with gender, the females were meaningfully older thanmales (p<0.05). It wasseen that the patients who smokes were younger than the patients who do not (p<0.05). It was seen that a large number of thepatients (57.6%) were the farmers who work in the open air and they weremeaningfully younger than other professional groups (p<0.05). A large number of the lesions weresquamous cell carcinoma (SCC) (88%). While 86% of the lesions in the patientswith SCC were localized on the lower lip, 70% of the lesions in the patientswith basal cell cancer were localized on the upper lip. There was nostatistical difference in terms of smoking and histopathological types(p>0.05). Lip cancers do not reflect the characteristics of the oral cavitytumors because of the differences in behavioral patterns and while the exposureto ultraviolet sun lights has an important role in the ethiology, it wasevaluated that smoking had a little contribution to the tumor development.  Key words: Lipcancer, epidemiology, ultraviolet, smoking

Anahtar Kelimeler

Lip cancer, epidemiology, ultraviolet, smoking

Kaynakça

• Parkin DM, Muir CS, Whelan SL, et al. Cancer incidence in five continents. Volume VII. IARC scientific publications no. 120. Lyon: International Agency for Research on Cancer, 1992.
• Abreu L, Kruger E, Tennant M. Lip cancer in Western Australia, 1982-2006: a 25-year retrospective epidemiological study. Aust Dent J 2009; 54: 130-135.
• Zide BM. Deformities of the lips and cheeks. In McCarthy JG (Ed) Plastic Surgery Vol.3. Philadelphia: WB Saunders Company. 1990; ch.38, p. 2009-27.
• Zitsch RP. Carcinoma of the lip. Otolaryngologic Clinics of North America 1993; 26: 265-277.
• Baker SR. Malignancy of the lip. In Paparella MM, Shumrick DA, Gluckman JL, Meyerhoff WL. (Eds) Otolaryngology Vol. 3, 3 rd ed. Philadelphia: WB Saunders Company. 1991; ch.16, p. 2021-39.
• Warnakulasuriya S. Global epidemiology of oral and oropharyngeal cancer. Oral Oncol 2008; 17: 3093
• Grossman D, Leffell DJ. The molecular basis of nonmelanoma skin cancer: new understanding. Arch Dermatol 1997; 133: 1263-1270.
• Erdibil HH, Yazıcı MF, Yücel Z, Bozkurt ER. Journal of Lip Cancers, ENT and Head-Neck Surgery 1995; 3: 231-235.
• Collins SL. Squamous cell carcinoma of the oral cavity, oropharynx, pharyngeal wall, and nasopharynx. In: Ballenger JJ, snow JB, editors. Otorhinolaryngology - Head and Neck Surgery, Translation editor: Çetin Kaleli, Nobel Tıp Publishing House 2000; p. 249-368.
• Perea-Milla López E, Miñarro-Del Moral RM, Martínez-García C, et al. Lifestyles, environmental and phenotypic factors associated with lip cancer: a case-control study in southern Spain. Br J Cancer 2003; 88: 1702-1707.
• Backer SR. Malignant neoplasms of the oral cavity. In: Cummings CW, Fredrickson IM, Harker LA, Krause Cl, Schuller DE, eds. Otolaryngology Head and Neck Surgery, 2nd ed. St. Louis: Mosby Year Book, 1992; p. 1248-1305.
• Chi AC. Epithelial pathology-lip vermilion carcinoma. In: Oral and Maxillofacial Pathology (Neville BW, Damm DD, Allen CM, Bouquot JE, eds), 3rd edn. Philadelphia: Saunders, 2009; p. 414– 4
• Czerninski R, Zini A, Sgan-Cohen HD. Lip cancer: incidence, trends, histology and survival: 1970-2006. Br J Dermatol 2010; 162: 1103-1109.
• International Agency for Research on Cancer. Solar and Ultraviolet Radiation. IARC Monographs on the Evaluation of the Carcinogenic Risks to Humans. 19 Available at: http://www.inchem.org/documents/iarc/vol55/solarand-uv-radiation.html (last accessed 22 February 2010).