Öz
Giriş ve Amaç: Linitis
plastika, diffüz infiltratif mide kanseri olup kötü prognoza sahiptir.
Endoskopik olarak spesifik bir bulgusu olmadığı için tanınması güçtür.
Endoskopik olarak şüphe edilse bile biyopsi ile tanı koymak da zor olabilir.
Biz burada kliniğimizde linitis plastika tanısı konulan olgularımızı endoskopik
özellikleri ile beraber paylaştık. Gereç
ve Yöntem: Bu çalışma retrospektif olarak Keçiören Eğitim ve Araştırma
Hastanesi, Gastroenteroloji Kliniğinde 2009-2019 tarihleri arasında
yürütülmüştür. Endoskopilerinde linitis plastika ön tanısı olan olgular bu
tarihler arasında toplanmıştır. Bulgular:
Toplam 28 hastadan linitis plastika ön tanısı ile biyopsi alınmış, bu
olguların 5 tanesinde linitis plastika tanısı konulmuştur. Linitis plastika olan
olguların hepsinde endoskopik olarak mide ekspansiyonunda kısıtlılık, gastrik
foldlarda belirginleşme, mukozal erozyon ve ülserler vardı. Sonuç: Linitis plastik için belirtilmiş
tipik bir endoskopik bulgu olmayıp mide ekspansiyonunda kısıtlılık ve gastrik
foldlarda belirginleşme olan olgularda klinik şüphenin yüksek olması gerekir.
İlk biyopsilerde linitis plastika tanısının konulmaması da sürpriz olmamalıdır.
Anahtar Kelimeler
Kaynakça
- 1- de Martel C, Forman D, Plummer M. Gastric cancer: epidemiology and risk factors. Gastroenterol Clin North Am 2013;42:219-40.
- 2- Waldum HL, Fossmark R. Types of gastric carcinomas. Int J Mol Sci 2018;19. pii: E4109
- 3- Hu B, El Hajj N, Sittler S, et al. Gastric cancer: Classification, histology and application of molecular pathology. J Gastrointest Oncol 2012;3:251-61.
- 4- Kajihara Y. Linitis plastica: 'leather bottle' stomach. QJM 2019;112:233-4.
- 5- London BW. The Disease of the Stomach. 1859:310.
- 6- Sah BK, Zhu ZG, Chen MM, et al. Gastric cancer surgery and its hazards: post operative infection is the most important complication. Hepatogastroenterology 2008;55:2259-63.
- 7- Shan GD, Xu GQ, Li YM. Endoscopic ultrasonographic features of gastric linitis plastica in fifty-five Chinese patients. J Zhejiang Univ Sci B 2013;14:844-8.
- 8- Liu CH, Yang AH, Ou SM, et al. The first reported case of cytomegalovirus gastritis in a patient with end-stage renal disease. Am J Med Sci 2018;355:607-9.
- 9- Ding Q, Lu P, Ding S, et al. Ménétrier disease manifested by polyposis and involved in both the small bowel and entire colon: A case report. Medicine (Baltimore) 2016;95:e4685.
- 10- Maeda E, Oryu M, Tani J, et al. Characteristic waffle-like appearance of gastric linitis plastica: A case report. Oncol Lett 2015;9:262-4.
- 11- Consul N, DiSantis DJ, Dyer RB. ‘The leather bottle’ stomach. Abdom Radiol (NY) 2018;43:2210-1.
- 12- Park MS, Ha HK, Choi BS, et al. Scirrhous gastric carcinoma: endoscopy versus upper gastrointestinal radiography. Radiology 2004;231:421-6.
Öz
Background and Aims: Linitis plastica
is known as diffuse infiltrative gastric carcinoma and has the worst prognosis.
Because it does not have a specific endoscopic appearance, diagnosing this
condition is difficult. Even if it is suspected in endoscopy, its pathology is
also challenging to comprehend. Here we presented our patients with linitis
plastica and their endoscopic appearances. Materials
and Methods: This is a retrospective study conducted in Kecioren Training and
Research Hospital between 2009 and 2019. Individuals with an initial endoscopic
diagnosis of linitis plastica were enrolled. Results:
Overall,
28 patients were suspected for linitis plastica; but only 5 had pathologic
diagnosis. These 5 patients had similar endoscopic characteristics, such as
gastric expansion limitation, hypertrophic gastric folds, erosions, and mucosal
ulcers. Conclusion: There is no specific
endoscopic appearance of linitis plastica; however, clinical suspicion must be
high in individuals who have gastric expansion limitation and hypertrophic
gastric folds. It must not be surprising if the first endoscopic biopsy result
is negative for adenocarcinoma in these patients.
Anahtar Kelimeler
Kaynakça
- 1- de Martel C, Forman D, Plummer M. Gastric cancer: epidemiology and risk factors. Gastroenterol Clin North Am 2013;42:219-40.
- 2- Waldum HL, Fossmark R. Types of gastric carcinomas. Int J Mol Sci 2018;19. pii: E4109
- 3- Hu B, El Hajj N, Sittler S, et al. Gastric cancer: Classification, histology and application of molecular pathology. J Gastrointest Oncol 2012;3:251-61.
- 4- Kajihara Y. Linitis plastica: 'leather bottle' stomach. QJM 2019;112:233-4.
- 5- London BW. The Disease of the Stomach. 1859:310.
- 6- Sah BK, Zhu ZG, Chen MM, et al. Gastric cancer surgery and its hazards: post operative infection is the most important complication. Hepatogastroenterology 2008;55:2259-63.
- 7- Shan GD, Xu GQ, Li YM. Endoscopic ultrasonographic features of gastric linitis plastica in fifty-five Chinese patients. J Zhejiang Univ Sci B 2013;14:844-8.
- 8- Liu CH, Yang AH, Ou SM, et al. The first reported case of cytomegalovirus gastritis in a patient with end-stage renal disease. Am J Med Sci 2018;355:607-9.
- 9- Ding Q, Lu P, Ding S, et al. Ménétrier disease manifested by polyposis and involved in both the small bowel and entire colon: A case report. Medicine (Baltimore) 2016;95:e4685.
- 10- Maeda E, Oryu M, Tani J, et al. Characteristic waffle-like appearance of gastric linitis plastica: A case report. Oncol Lett 2015;9:262-4.
- 11- Consul N, DiSantis DJ, Dyer RB. ‘The leather bottle’ stomach. Abdom Radiol (NY) 2018;43:2210-1.
- 12- Park MS, Ha HK, Choi BS, et al. Scirrhous gastric carcinoma: endoscopy versus upper gastrointestinal radiography. Radiology 2004;231:421-6.
Ayrıntılar
| Birincil Dil | Türkçe |
|---|---|
| Konular | Sağlık Kurumları Yönetimi |
| Bölüm | Makaleler |
| Yazarlar | |
| Yayımlanma Tarihi | 18 Eylül 2019 |
| Yayımlandığı Sayı | Yıl 2019 Cilt: 27 Sayı: 2 |
