Bir Kedide Omuz Bölgesindeki Osteosarkom Olgusunun Histopatolojik Değerlendirilmesi

Yıl 2015, Cilt: 12 Sayı: 1, 57 - 61, 01.04.2015

Ayhan Atasever Gültekin Atalan Duygu Yaman Murat Kibar

Öz

Bu çalışmanın materyalini, 8 yaşlı, dişi, melez bir kedinin sol skapulası üzerindeki, yaklaşık 5x3x2 cm boyutlarında

operasyon ile alınan bir kitle oluşturdu. Klinik muayenede, yeme ve içme durumunun normal olduğu ancak yürüme

esnasında omuz bölgesindeki kitleye bağlı gelişen topallıktan kaynaklanan bir yürüyüş bozukluğu görüldü.Operasyon

ile alınan kitlenin elastik kıvamda, kesit yüzünün gri-beyazımtırak renkte olduğu ve nekrotik alanların varlığı dikkati

çekti. Mikroskobik olarak, fibrosarkomatöz alanlar, solid tarzda yerleşim gösteren kıkırdak hücrelerine benzer, anaplastik

karakterde pleomorfik hücrelerden oluşan alanlar ve birbirleri ile kaynaşmış anaplastik karakterde osteoblastlardan

oluşan kemik trabekül yapıları gözlendi. Anamnez, klinik bulgular ve histopatolojik incelemeler sonucu olguya aşı ilişkili

osteosarkom tanısı konuldu.

Anahtar Kelimeler

Aşı, kedi, osteosarkom

Histopathological Evaluation of Osteosarcoma of the Shoulder Region in a Cat

Öz

The material of this study consisted of a piece of mass which operatively removed from an eight year old,

female, half-breed cat. In the physical examination, the situation of drinking and eating were found normally. However

there was a walking disorder associated with shoulder lameness. The cross-section of this mass was in grey-white

colour, elastic consistency and there were some necrotic areas. Microscopically, mononuclear cell infiltration areas

which were situated around the fibrocytes, fibroblasts and collagen bundles or infiltrating in dermis were observed.

Bone trabecular were formed by anaplastic osteoblasts that fused with each other and also solid areas which

composed by chondrocytes like anaplastic pleomorphic cells were noticed. The history, clinical and histopathological

investigations revealed that the characteristic of mass was feline vaccine-associated osteosarcoma.

Anahtar Kelimeler

Cat, osteosarcoma, vaccine

Kaynakça

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