BESİNLER VE BAZI BESİN ÖĞELERİNİN AKCİĞER KANSERİYLE İLİŞKİSİ
Yıl 2018,
Cilt: 5 Sayı: 1-2, 8 - 16, 28.12.2018
Mehmet Çavdar
,
Meliha Çavdar
Öz
Besinler ve bazı besin öğeleri ile akciğer kanseri arasındaki
ilişki, içme suyundaki arseniğin karsinojen olarak net bir
biçimde belirtilmesinin dışında henüz açıklığa kavuşturulamamıştır. Mevcut literatürdeki çalışmalar ve konu hakkında
otorite kabul edilen kurumlar; sebze ve meyvelerle birlikte
karotenoidler, izoflavonlar, retinol ve C vitamini içeren
besinlerin akciğer kanseri oluşumunun önlenmesinde faydalı
olabileceğini belirtmiştir. Öte yandan kırmızı ya da işlenmiş
et tüketimi ile alkol alımının ise akciğer kanserine sebep
olabileceğine dair bazı çalışmalar da bulunmaktadır.
Kaynakça
- Alexandrov K, Cascorbi I, Rojas M, et al.
CYP1A1 and GSTM1 genotypes affect
benzo[a]pyrene DNA adducts in smokers’ lung: comparison with aromatic
/hydrophobic adduct formation. Carcinogenesis. 2002; 23:1967-1969.
- Baastrup R, Sorensen M, Balstrom T, et al.
Arsenic in drinking-water and risk for
cancer in Denmark. Environ Health
Perspect. 2008; 116:231-237.
- Chen CL, Chiou HY, Hsu LI, et al. Ingested
arsenic, characteristics of well water
consumption and risk of different histological types of lung cancer in northeastern Taiwan. Environ Res. 2010;
110:455-462.
- Chung CJ, Huang YL, Huang YK, et al. Urinary arsenic profiles and the risks of
cancer mortality: a population-based 20-
year follow-up study in arseniasisendemic areas in Taiwan. Environ Res.
2013; 122:25-30
- Fountoulakis A, Martin IG, White KL, et al.
Plasma and esophageal mucosal levels
of vitamin C; role in the pathogenesis
and neoplastic progression of Barret’s
esophageus. Dig Dis Sci. 2004; 49:914-
919
- Goldman R, Shields PG. Food Mutagens. J
Nutr. 2003; 133:965-973
International Agency for Research on Cancer.
- IARC monographs on the evaluation of
carcinogenic risk to humans. Erişim:
30/11/2018
https://monographs.iarc.fr/wpcontent/uploads/2018/06/mono100C-
6.pdf.
- International Agency for Research on Cancer.
IARC monographs on the evaluation of
carcinogenic risk to humans: Alcohol
consumption and ethyl carbamate. Eri-
şim: 30/11/2018
https://monographs.iarc.fr/wpcontent/uploads/2018/06/mono96.pdf.
- Key TJ, Schatzkin A, Willet WC, et al. Diet,
nutrition and the prevention of cancer.
Public Health Nutr. 2004; 7:187–200
- Khan MM, Goto R, Kobayashi K, et al. Dietary habits and cancer mortality among
middle aged and older Japanese livingin
Hokkaido, Japan by cancer site and sex.
Asian Pac J Cancer Prev. 2004; 5:58–65
- Levine N, Meyskens FL. Topical vitamin-Aacid therapy for cutaneous metastatic
melanoma. Lancet. 1980; 2:224-226
- Sawada N, Iwasaki M, Inoue M, et al. Dietary
arsenic intake and subsequent risk of
cancer: the Japan Public Health Centerbased (JHPC) Prospective Study. Cancer
Causes Control. 2013; 24:1403-1415
- Takata Y, Xiang YB, Yang G, et al. Intakes of
fruits, vegetables, and related vitamins
and lung cancer risk: results from the
- Shanghai Men’s Health Study (2002-
2009). Nutr Cancer. 2013; 65:51-61
- World Cancer Research Fund. Global cancer
statisitcs for the most common cancers.
Erişim Tarihi: 30/11/2018
https://www.wcrf.org/dietandcancer/can
cer-trends/worldwide-cancer-data.
- World Cancer Research Fund. Diet, nutrition,
physical activity and lung cancer. Eri-
şim: 30/11/2018
https://www.wcrf.org/sites/default/files/
Lung-cancer-report.pdf.
- World Cancer Research Fund International
Systematic Literature Review. The Associations between Food, Nutrition and
Physical Activity and the Risk of Lung
Cancer. Erişim: 30/11/2018
https://www.wcrf.org/sites/default/files/
Lung-cancer-slr.pdf.
- World Cancer Research Fund. Food, Nutrition,
Physical Activity, and the Prevention of
Cancer: a Global Perspective. Erişim:
30/11/2018
http://www.aicr.org/assets/docs/pdf/repo
rts/Second_Expert_Report.pdf.
- Xue XJ, Gao Q, Qiao JH, et al. Red and processed meat consumption and the risk of
lung cancer: a dose-response metaanalysis of 33 published studies. Int J
Clin Exp Med. 2014; 7:1542-1553
- Yang WS, Wong MY, Vogtmann E, et al.
Meat consumption and risk of lung cancer: evidence from observational studies.
Ann Oncol. 2012; 23:3163-3170
ASSOCIATION OF FOODS AND SOME NUTRIENTS WITH LUNG CANCER
Yıl 2018,
Cilt: 5 Sayı: 1-2, 8 - 16, 28.12.2018
Mehmet Çavdar
,
Meliha Çavdar
Öz
The relationship between foods, some nutrients and lung
cancer has not been elucidated yet, except that the arsenic in
drinking water is clearly as carcinogen. Studies in the current literature and institutions considered to be authoritative
about cancer suggested that vegetables and fruits with carotenoids, isoflavones, retinol and vitamin C containing foods
may be useful in the prevention of lung cancer. On the other
hand, some studies indicated that consumption of red or
processed meat and alcohol intake may cause lung cancer.
Kaynakça
- Alexandrov K, Cascorbi I, Rojas M, et al.
CYP1A1 and GSTM1 genotypes affect
benzo[a]pyrene DNA adducts in smokers’ lung: comparison with aromatic
/hydrophobic adduct formation. Carcinogenesis. 2002; 23:1967-1969.
- Baastrup R, Sorensen M, Balstrom T, et al.
Arsenic in drinking-water and risk for
cancer in Denmark. Environ Health
Perspect. 2008; 116:231-237.
- Chen CL, Chiou HY, Hsu LI, et al. Ingested
arsenic, characteristics of well water
consumption and risk of different histological types of lung cancer in northeastern Taiwan. Environ Res. 2010;
110:455-462.
- Chung CJ, Huang YL, Huang YK, et al. Urinary arsenic profiles and the risks of
cancer mortality: a population-based 20-
year follow-up study in arseniasisendemic areas in Taiwan. Environ Res.
2013; 122:25-30
- Fountoulakis A, Martin IG, White KL, et al.
Plasma and esophageal mucosal levels
of vitamin C; role in the pathogenesis
and neoplastic progression of Barret’s
esophageus. Dig Dis Sci. 2004; 49:914-
919
- Goldman R, Shields PG. Food Mutagens. J
Nutr. 2003; 133:965-973
International Agency for Research on Cancer.
- IARC monographs on the evaluation of
carcinogenic risk to humans. Erişim:
30/11/2018
https://monographs.iarc.fr/wpcontent/uploads/2018/06/mono100C-
6.pdf.
- International Agency for Research on Cancer.
IARC monographs on the evaluation of
carcinogenic risk to humans: Alcohol
consumption and ethyl carbamate. Eri-
şim: 30/11/2018
https://monographs.iarc.fr/wpcontent/uploads/2018/06/mono96.pdf.
- Key TJ, Schatzkin A, Willet WC, et al. Diet,
nutrition and the prevention of cancer.
Public Health Nutr. 2004; 7:187–200
- Khan MM, Goto R, Kobayashi K, et al. Dietary habits and cancer mortality among
middle aged and older Japanese livingin
Hokkaido, Japan by cancer site and sex.
Asian Pac J Cancer Prev. 2004; 5:58–65
- Levine N, Meyskens FL. Topical vitamin-Aacid therapy for cutaneous metastatic
melanoma. Lancet. 1980; 2:224-226
- Sawada N, Iwasaki M, Inoue M, et al. Dietary
arsenic intake and subsequent risk of
cancer: the Japan Public Health Centerbased (JHPC) Prospective Study. Cancer
Causes Control. 2013; 24:1403-1415
- Takata Y, Xiang YB, Yang G, et al. Intakes of
fruits, vegetables, and related vitamins
and lung cancer risk: results from the
- Shanghai Men’s Health Study (2002-
2009). Nutr Cancer. 2013; 65:51-61
- World Cancer Research Fund. Global cancer
statisitcs for the most common cancers.
Erişim Tarihi: 30/11/2018
https://www.wcrf.org/dietandcancer/can
cer-trends/worldwide-cancer-data.
- World Cancer Research Fund. Diet, nutrition,
physical activity and lung cancer. Eri-
şim: 30/11/2018
https://www.wcrf.org/sites/default/files/
Lung-cancer-report.pdf.
- World Cancer Research Fund International
Systematic Literature Review. The Associations between Food, Nutrition and
Physical Activity and the Risk of Lung
Cancer. Erişim: 30/11/2018
https://www.wcrf.org/sites/default/files/
Lung-cancer-slr.pdf.
- World Cancer Research Fund. Food, Nutrition,
Physical Activity, and the Prevention of
Cancer: a Global Perspective. Erişim:
30/11/2018
http://www.aicr.org/assets/docs/pdf/repo
rts/Second_Expert_Report.pdf.
- Xue XJ, Gao Q, Qiao JH, et al. Red and processed meat consumption and the risk of
lung cancer: a dose-response metaanalysis of 33 published studies. Int J
Clin Exp Med. 2014; 7:1542-1553
- Yang WS, Wong MY, Vogtmann E, et al.
Meat consumption and risk of lung cancer: evidence from observational studies.
Ann Oncol. 2012; 23:3163-3170