ASSOCIATION BETWEEN VITAMIN D STATUS AND ASTHMA CONTROL IN ADULTS

Yıl 2023, Cilt: 4 Sayı: Ek Sayı, 195 - 200, 16.10.2023

Bilge Salık , Merve Ayık Türk , Özgür Batum , Berna Kömürcüoğlu

Öz

Introduction: Asthma is a chronic respiratory disease associated with airway inflammation. In some diseases such as vascular diseases and diabetes mellitus, the role of diet in the control of the disease is emphasized, but it is not defined as a similar causal factor in asthma. This study was planned to evaluate the relationship between vitamin D status and asthma-related respiratory results.
Methods: This single-center retrospective cohort study examined a total of 87 patients diagnosed with asthma. Vitamin D levels that were checked for any reason in the past 1 month were included in the present study. The asthma control status of the patients was determined by the Asthma Control Test (ACT). The statistical relationship between asthma control and vitamin D levels of the patients was examined.
Results: According to ACT results, 43 of the patients had controlled asthma and 44 had uncontrolled asthma. The median vitamin D level of all cases was found to be 12.80 (8.83-10.66). When vitamin D levels were compared between the controlled and uncontrolled asthma groups, they were statistically significant (p<0.001).
Conclusion: The present study showed that there is an association between low vitamin D levels and uncontrolled asthma and the researchers focused on the effect of diet on asthma-related respiratory outcomes and asthma control. Considering the cost- effectiveness, it is thought that monitoring vitamin D levels in asthma control and vitamin D replacement when necessary will contribute to the clinicians.

Anahtar Kelimeler

Asthma, Vitamin D, asthma control test

Proje Numarası

Yok

ERİŞKİNLERDE D VİTAMİNİ DÜZEYİ İLE ASTIM KONTROLÜ ARASINDAKİ İLİŞKİ

Öz

Giriş: Astım, hava yolu inflamasyonu ile ilişkili kronik solunum yolu hastalığıdır. Vasküler hastalıklar ve diabetes mellitus gibi bazı hastalıklarda, diyetin hastalığın kontrolündeki rolü vurgulanırken, astımda benzer bir nedensel faktör olarak tanımlanmamaktadır. Bu çalışmada, D vitamini düzeyi ile astım ilişkili solunum parametreleri arasındaki ilişkiyi değerlendirmek amaçlanmıştır.
Yöntemler: Bu çalışmada, astım tanısı konan toplam 87 hasta, tek merkezli retrospektif kohort olarak incelendi. Son 1 ay içinde herhangi bir nedenle D vitamini düzeyleri kontrol edilen hastalar çalışmaya dahil edildi. Hastaların astım kontrol durumu, Astım Kontrol Testi (AKT) ile belirlendi. Hastaların astım kontrolü ile D vitamini düzeyleri arasındaki istatistiksel ilişki incelendi.
Bulgular: AKT sonuçlarına göre, hastaların 43'ü kontrollü astım, 44'ü ise kontrolsüz astımdı. Tüm olguların medyan D vitamini düzeyi 12.80 (8.83-10.66) olduğu bulundu. D vitamini düzeyleri, kontrollü ve kontrolsüz astım gruplarında karşılaştırıldığında, aradaki fark istatistiksel olarak anlamlı bulundu (p<0.001).
Sonuç: Çalışmada diyetin astım ilişkili solunum parametreleri ve astım kontrolü üzerindeki etkisine odaklanılmıştır ve düşük D vitamini düzeyleri ile kontrolsüz astım arasında bir ilişki olduğunu gösterilmiştir. Maliyet-etkinlik göz önünde bulundurulduğunda astım kontrolünde, D vitamini düzeylerinin takibinin ve gerektiğinde D vitamini replasmanının yapılması, astım kontrolünün sağlanmasında, klinisyenlere katkı sağlayacağı düşünülmektedir.

Anahtar Kelimeler

Astım, D vitamini, astım kontrol testi

Destekleyen Kurum

Yok

Proje Numarası

Yok

Teşekkür

yok

Kaynakça

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