Araştırma Makalesi
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Yıl 2019, Cilt: 1 Sayı: 1, 7 - 11, 30.12.2019

Hüsniye Yücel , Ayşen Sumru Kavurt , Beyza Özcan , Dilek Ulubas , Ahmet Yağmur Baş , Nihal Demirel

Öz

Kaynakça

  • 1. Seger N, Soll R. Animal derived surfactant extract for treatment of respiratory distress syndrome. Cochrane Database Syst Rev. 2009 Apr 15;(2):CD007836
  • 2. Soll RF, McQueen MC. Respiratory Distress Syndrome.In:Sinclair JC, Bracken MB editor(s).Effective Care of the Newborn Infant.Oxford:Oxford University Pres,1992.
  • 3. Engle WA. American Academy of Pediatrics Committee on Fetus and Newborn. Surfactantreplacement therapy for respiratory distress in the preterm and term neonate. Pediatrics. 2008;121(2):419–432.
  • 4. Finer NN. Surfactant use for neonatal lung injury: beyond respiratory distress syndrome. Paediatr Respir Rev. 2004; 5(suppl A):S289–S297.
  • 5. Bissinger R, Carlson C, Hulsey T, Eicher D. Secondary surfactant deficiency in neonates. J Perinatol 2004, 24:663–666.
  • 6. Donn SM, Dalton J. Surfactant replacement therapy in the neonate: beyond respiratory distress syndrome. Respir Care. 2009;54(9):1203–1208.
  • 7. Lotze A, Knight GR, Martin GR, et al. Improved pulmonary outcome after exogenous surfactant therapy for respiratory failure in term infants requiring extracorporeal membrane oxygenation. J Pediatr. 1993;122(2):261–268.
  • 8. Barnett ED, Klein JO. Bacterial Infections of the Respiratory Tract.In:Infectious Diseases of the Fetus and the Newborn, 7th ed, Remington JS, et al (Eds).Elservier Saunders ,Philadelphia 2010.p.276.
  • 9. Rawlings JS, Smith FR. Transient tachypnea of the newborn an analysis of neonatal and obstetric risk factors. Am J Dis Child 1984; 138:869– 871.
  • 10. Dargaville PA, Copnell B; Australian and New Zealand Neonatal Network. The epidemiology of meconium aspiration syndrome: incidence,risk factors, therapies and outcome. Pediatrics 2006;117:1712.
  • 11. Jalal M. Respiratory Disorders in Preterm and Term Infants. In: Martin RJ, Fanaroff AA, Walsh MC, eds. Fanaroff and Martin’s Neonatal –Perinatal Medicine Diseases of the Fetus and Infant. 9 th ed. St.Louis: Elsevier;2011.p.1141-70
  • 12. El Shahed AI, Dargaville P, Ohlsson A, Soll RF. Surfactant for meconium aspiration syndrome in full term/near term infants. Cochrane Database Syst Rev. 2007 Jul 18;(3):CD002054.
  • 13. Auten RL, Notter RH, Kendig, JW, Davis JM, Shapiro DL. Surfactant treatment of full-term newborns with respiratory failure. Pediatrics 1991; 87:101-107.
  • 14. Oh MH, Bae CW: Inhibitory effect of meconium on pulmonary surfactant function tested in vitro using the stable microbubble test. Eur J Pediatr 2000, 159:770–774.
  • 15. Herting E, Gefeller O, Land M, van Sonderen L, Harms K, Robertson B. Surfactant treatment of neonates with respiratory failure and group B streptococcal infection. Members of the Collaborative European Multicenter Study Group. Pediatrics 2000;106(5):957–964.
  • 16. Avery ME, Gatewood OB, Brumley G. Transient tachypnea of newborn. Possible delayed resorption of fluid at birth. Am J Dis Child 1966; 111: 380–385.
  • 17. Miller LK, Calenoff L, Boehm JJ, et al. Respiratory distress in the newborn. JAMA 1980; 243: 1176–1179.
  • 18. Machado LU, Fiori HH, Baldisserotto M, Ramos Garcia PC, Vieira AC, Fiori RM: Surfactant deficiency in transient tachypnea of the newborn. J Pediatr 2011, 159:750–754.
  • 19. Gomella TL. Transient tachypnea of the Newborn. In. Neonatology 7 th ed.Langep.919.
  • 20. Soll RF, Dargaville P. Surfactant for meconium aspiration syndrome in full term infants. Cochrane Database Syst Rev. 2000;(2):CD002054.
  • 21. Benachi A, Chailley-Heu B, Barlier-Mur AM, Dumez Y, Bourbon J: Expression of surfactant proteins and thyroid transcription factor 1 in an ovine model of congenital diaphragmatic hernia. J Pediatr Surg 2002, 37:1393–1398.
  • 22. Thébaud B, Barlier-Mur AM, Chailley-Heu B, Henrion-Caude A, Tibboel D, Dinh-Xuan AT, Bourbon JR: Restoring effects of vitamin A on surfactant synthesis in nitrofen-induced congenital diaphragmatic hernia in rats. Am J Respir Crit Care Med 2001, 164:1083–1089.
  • 23. Moya FR, Thomas VL, Romaguera J, Mysore MR, Maberry M, Bernard A, Freund M: Fetal lung maturation in congenital diaphragmatic hernia. Am J Obstet Gynecol 1995, 173:1401–1405.
  • 24. Mysore MR, Margraf LR, Jaramillo MA, Breed DR, Chau VL, Arévalo M, Moya FR: Surfactant protein A is decreased in a rat model of congenital diaphragmatic hernia. Am J Respir Crit Care Med 1998, 157:654–657.
  • 25. Lally KP, Lally PA, Langham MR, Hirschl R, Moya FR, Tibboel D, Van Meurs K, Congenital Diaphragmatic Hernia Study Group: Surfactant does not improve survival rate in preterm infants with congenital diaphragmatic hernia. J Pediatr Surg 2004, 39:829–833.

Surfactant Treatment for Neonatal Respiratory Disorders in Late Preterm and Term Infants

Yıl 2019, Cilt: 1 Sayı: 1, 7 - 11, 30.12.2019

Hüsniye Yücel , Ayşen Sumru Kavurt , Beyza Özcan , Dilek Ulubas , Ahmet Yağmur Baş , Nihal Demirel

Öz

Amaç: Surfaktan tedavisinin, solunum yetmezliği olan geç preterm ve term bebeklerde gaz değişimini iyileştirmede etkili olduğu gösterilmiştir.Ancak bu bebeklerde surfaktan uygulaması ile ilgili öneriler net değildir. Bu çalışmada, solunum yetmezliği nedeni ile surfaktan tedavisi uygulanan geç preterm ve term bebeklerin değerlendirilmesi amaçlanmıştır.
Gereç ve Yöntem: 2011-2013 yılları arasında, gestasyon yaşı 34 hafta ve üzerinde olan RDS dışı akciğer hastalığı nedeni ilesurfaktan uygulanan hastalar retrospektif olarak incelendi.
Bulgular: Çalışma süresince gestasyon yaşı 34 haftanın üzerinde olan 3212 hasta yenidoğan yoğun bakım ünitesine yatırıldı. Bu hastaların 28’ine (16 erkek/12 kız) solunum yetmezliği nedeni ile surfaktan uygulandı. Hastaların ortalama doğum ağırlığı 2907±145 gr, ortalama doğum haftası 36,14±0,52 hafta idi. Surfaktan uygulanan hastaların 16’sında (%57,2) neonatal pnömoni, 6’sında(%21,4) yenidoğanın geçici takipnesi, 4’ünde (%14,2) MAS, 2’sinde (%7,1) pulmoner hipoplazi saptandı. Surfaktan uygulanma zamanı ortalama 1,85±0,44 gün saptandı.
Sonuç: Sekonder surfaktan eksikliği geç preterm ve term bebeklerde ciddi solunum yetmezliğine neden olabilir. Bu bebeklerde solunum destek tedavisinde surfaktan kullanılabilir. Ancak geç preterm ve term bebeklerde sekonder surfaktan eksikliğinde surfaktan kullanımı ile ilgili ek çalışmalar gerekmektedir.

Anahtar Kelimeler

Surfactant

Kaynakça

  • 1. Seger N, Soll R. Animal derived surfactant extract for treatment of respiratory distress syndrome. Cochrane Database Syst Rev. 2009 Apr 15;(2):CD007836
  • 2. Soll RF, McQueen MC. Respiratory Distress Syndrome.In:Sinclair JC, Bracken MB editor(s).Effective Care of the Newborn Infant.Oxford:Oxford University Pres,1992.
  • 3. Engle WA. American Academy of Pediatrics Committee on Fetus and Newborn. Surfactantreplacement therapy for respiratory distress in the preterm and term neonate. Pediatrics. 2008;121(2):419–432.
  • 4. Finer NN. Surfactant use for neonatal lung injury: beyond respiratory distress syndrome. Paediatr Respir Rev. 2004; 5(suppl A):S289–S297.
  • 5. Bissinger R, Carlson C, Hulsey T, Eicher D. Secondary surfactant deficiency in neonates. J Perinatol 2004, 24:663–666.
  • 6. Donn SM, Dalton J. Surfactant replacement therapy in the neonate: beyond respiratory distress syndrome. Respir Care. 2009;54(9):1203–1208.
  • 7. Lotze A, Knight GR, Martin GR, et al. Improved pulmonary outcome after exogenous surfactant therapy for respiratory failure in term infants requiring extracorporeal membrane oxygenation. J Pediatr. 1993;122(2):261–268.
  • 8. Barnett ED, Klein JO. Bacterial Infections of the Respiratory Tract.In:Infectious Diseases of the Fetus and the Newborn, 7th ed, Remington JS, et al (Eds).Elservier Saunders ,Philadelphia 2010.p.276.
  • 9. Rawlings JS, Smith FR. Transient tachypnea of the newborn an analysis of neonatal and obstetric risk factors. Am J Dis Child 1984; 138:869– 871.
  • 10. Dargaville PA, Copnell B; Australian and New Zealand Neonatal Network. The epidemiology of meconium aspiration syndrome: incidence,risk factors, therapies and outcome. Pediatrics 2006;117:1712.
  • 11. Jalal M. Respiratory Disorders in Preterm and Term Infants. In: Martin RJ, Fanaroff AA, Walsh MC, eds. Fanaroff and Martin’s Neonatal –Perinatal Medicine Diseases of the Fetus and Infant. 9 th ed. St.Louis: Elsevier;2011.p.1141-70
  • 12. El Shahed AI, Dargaville P, Ohlsson A, Soll RF. Surfactant for meconium aspiration syndrome in full term/near term infants. Cochrane Database Syst Rev. 2007 Jul 18;(3):CD002054.
  • 13. Auten RL, Notter RH, Kendig, JW, Davis JM, Shapiro DL. Surfactant treatment of full-term newborns with respiratory failure. Pediatrics 1991; 87:101-107.
  • 14. Oh MH, Bae CW: Inhibitory effect of meconium on pulmonary surfactant function tested in vitro using the stable microbubble test. Eur J Pediatr 2000, 159:770–774.
  • 15. Herting E, Gefeller O, Land M, van Sonderen L, Harms K, Robertson B. Surfactant treatment of neonates with respiratory failure and group B streptococcal infection. Members of the Collaborative European Multicenter Study Group. Pediatrics 2000;106(5):957–964.
  • 16. Avery ME, Gatewood OB, Brumley G. Transient tachypnea of newborn. Possible delayed resorption of fluid at birth. Am J Dis Child 1966; 111: 380–385.
  • 17. Miller LK, Calenoff L, Boehm JJ, et al. Respiratory distress in the newborn. JAMA 1980; 243: 1176–1179.
  • 18. Machado LU, Fiori HH, Baldisserotto M, Ramos Garcia PC, Vieira AC, Fiori RM: Surfactant deficiency in transient tachypnea of the newborn. J Pediatr 2011, 159:750–754.
  • 19. Gomella TL. Transient tachypnea of the Newborn. In. Neonatology 7 th ed.Langep.919.
  • 20. Soll RF, Dargaville P. Surfactant for meconium aspiration syndrome in full term infants. Cochrane Database Syst Rev. 2000;(2):CD002054.
  • 21. Benachi A, Chailley-Heu B, Barlier-Mur AM, Dumez Y, Bourbon J: Expression of surfactant proteins and thyroid transcription factor 1 in an ovine model of congenital diaphragmatic hernia. J Pediatr Surg 2002, 37:1393–1398.
  • 22. Thébaud B, Barlier-Mur AM, Chailley-Heu B, Henrion-Caude A, Tibboel D, Dinh-Xuan AT, Bourbon JR: Restoring effects of vitamin A on surfactant synthesis in nitrofen-induced congenital diaphragmatic hernia in rats. Am J Respir Crit Care Med 2001, 164:1083–1089.
  • 23. Moya FR, Thomas VL, Romaguera J, Mysore MR, Maberry M, Bernard A, Freund M: Fetal lung maturation in congenital diaphragmatic hernia. Am J Obstet Gynecol 1995, 173:1401–1405.
  • 24. Mysore MR, Margraf LR, Jaramillo MA, Breed DR, Chau VL, Arévalo M, Moya FR: Surfactant protein A is decreased in a rat model of congenital diaphragmatic hernia. Am J Respir Crit Care Med 1998, 157:654–657.
  • 25. Lally KP, Lally PA, Langham MR, Hirschl R, Moya FR, Tibboel D, Van Meurs K, Congenital Diaphragmatic Hernia Study Group: Surfactant does not improve survival rate in preterm infants with congenital diaphragmatic hernia. J Pediatr Surg 2004, 39:829–833.
Toplam 25 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Çocuk Sağlığı ve Hastalıkları
Bölüm Araştırma Makalesi
Yazarlar

Hüsniye Yücel 0000-0002-7477-0302

Ayşen Sumru Kavurt 0000-0003-0329-1846

Beyza Özcan 0000-0002-2834-5823

Dilek Ulubas 0000-0001-9937-4624

Ahmet Yağmur Baş 0000-0002-1329-2167

Nihal Demirel 0000-0003-2044-2212

Yayımlanma Tarihi 30 Aralık 2019
Kabul Tarihi 30 Aralık 2019
Yayımlandığı Sayı Yıl 2019 Cilt: 1 Sayı: 1

Kaynak Göster

APA Yücel, H., Kavurt, A. S., Özcan, B., Ulubas, D., vd. (2019). Surfactant Treatment for Neonatal Respiratory Disorders in Late Preterm and Term Infants. Türk Kadın Sağlığı Ve Neonatoloji Dergisi, 1(1), 7-11.
AMA Yücel H, Kavurt AS, Özcan B, Ulubas D, Baş AY, Demirel N. Surfactant Treatment for Neonatal Respiratory Disorders in Late Preterm and Term Infants. Türk Kadın Sağlığı ve Neonatoloji Dergisi. Aralık 2019;1(1):7-11.
Chicago Yücel, Hüsniye, Ayşen Sumru Kavurt, Beyza Özcan, Dilek Ulubas, Ahmet Yağmur Baş, ve Nihal Demirel. “Surfactant Treatment for Neonatal Respiratory Disorders in Late Preterm and Term Infants”. Türk Kadın Sağlığı Ve Neonatoloji Dergisi 1, sy. 1 (Aralık 2019): 7-11.
EndNote Yücel H, Kavurt AS, Özcan B, Ulubas D, Baş AY, Demirel N (01 Aralık 2019) Surfactant Treatment for Neonatal Respiratory Disorders in Late Preterm and Term Infants. Türk Kadın Sağlığı ve Neonatoloji Dergisi 1 1 7–11.
IEEE H. Yücel, A. S. Kavurt, B. Özcan, D. Ulubas, A. Y. Baş, ve N. Demirel, “Surfactant Treatment for Neonatal Respiratory Disorders in Late Preterm and Term Infants”, Türk Kadın Sağlığı ve Neonatoloji Dergisi, c. 1, sy. 1, ss. 7–11, 2019.
ISNAD Yücel, Hüsniye vd. “Surfactant Treatment for Neonatal Respiratory Disorders in Late Preterm and Term Infants”. Türk Kadın Sağlığı ve Neonatoloji Dergisi 1/1 (Aralık 2019), 7-11.
JAMA Yücel H, Kavurt AS, Özcan B, Ulubas D, Baş AY, Demirel N. Surfactant Treatment for Neonatal Respiratory Disorders in Late Preterm and Term Infants. Türk Kadın Sağlığı ve Neonatoloji Dergisi. 2019;1:7–11.
MLA Yücel, Hüsniye vd. “Surfactant Treatment for Neonatal Respiratory Disorders in Late Preterm and Term Infants”. Türk Kadın Sağlığı Ve Neonatoloji Dergisi, c. 1, sy. 1, 2019, ss. 7-11.
Vancouver Yücel H, Kavurt AS, Özcan B, Ulubas D, Baş AY, Demirel N. Surfactant Treatment for Neonatal Respiratory Disorders in Late Preterm and Term Infants. Türk Kadın Sağlığı ve Neonatoloji Dergisi. 2019;1(1):7-11.
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