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KÖPEK ATOPİK DERMATİTİSİNDE TEŞHİS VE ALERJEN TAYİNİNDEKİ GÜNCEL YAKLAŞIMLAR

Yıl 2018, Cilt: 27 Sayı: 2, 176 - 181, 01.07.2018

Öz

Köpek atopik dermatitis (KAD), genetik yatkınlığı olan
inflamatuar ve kaşıntılı bir deri hastalığıdır. Hastalığın
klinik bulgularındaki farklılaşma, genetik faktörlere
bağlı klinik bulgular, lezyonların derecesi ve sekonder
enfeksiyonların varlığı diğer deri hastalıklarına benzerlik gösterebileceği için atopik dermatitis (AD) tanısını
karmaşık hale getirebilir. Köpek AD tanısını koyabilmek
için benzer klinik kriterleri ve bulguları taşıyan olası
tüm nedenler ekarte edilmelidir. Tüm bunlardan sonra
KAD tanısı konulan hastalarda alerji testleri ile potansiyel alerjenlerin kimliğinin belirlenerek buna özgü alerjen spresifik immunoterapi uygulamasına başlanılmalıdır.

Kaynakça

  • 1. Halliwell R. Revised nomenclature for veterinary allergy. Vet Immunol Immunopathol 2006; 114:207 -208.
  • 2. DeBoer DJ, Hillier A. The ACVD task force on canine atopic dermatitis (XV): fundamental concepts in clinical diagnosis. Vet Immunol Immunopathol 2001; 81:271-276.
  • 3. Nuttall T. The genomics revolution: will canine atopic dermatitis be predictable and preventable? Vet Dermatol 2013; 24:13-14.
  • 4. Aytuğ N, Kanat Ö, Kömürcü B. Köpeklerin atopik dermatitisi. Turkiye Klinikleri J Vet Sci Intern MedSpecial Topics 2017; 3:202-208.
  • 5. Olivry T, DeBoer DJ, Favrot C, et al. Treatment of canine atopic dermatitis: 2015 updated guidelines from the International Committee on Allergic Diseases of Animals (ICADA). BMC Veterinary Research 2015; 11: 210.
  • 6. Favrot C, Steffan J, Seewald W, et al. A prospective study on the clinical features of chronic canine atopic dermatitis and its diagnosis. Vet Dermatol 2010; 21:23-31.
  • 7. Willemse TA. Atopic dermatitis: a review and reconsideration of diagnostic criteria. JSAP 1986; 27: 771 -778.
  • 8. Pre´laud P, Guague`re E, Alhaidari Z, et al. Reevaluation of diagnostic criteria of canine atopic dermatitis. Rev Med Vet 1998; 149:1057-1064.
  • 9. Hensel P, Santoro D, Favrot C, et al. Canine atopic dermatitis: detailed guidelines for diagnosis and allergen identification. BMC Veterinary Research 2015; 11: 1-13.
  • 10. Bruet V, Bourdeau PJ, Roussel A, Imparato L, Desfontis JC. Characterization of pruritus in canine atopic dermatitis, flea bite hypersensitivity and flea infestation and its role in diagnosis. Vet Dermatol 2012; 23:487-493.
  • 11. Miller WH, Griffin CE. Campbell KL. In: Small Animal Dermatology. 7th ed. St.Louis: WB Elsevier. 2013; p 363-431.
  • 12. Olivry T, Deboer DJ, Prelaud P, Bensignor E. International Task Force on Canine Atopic Dermatitis. Food for thought: pondering the relationship between canine atopic dermatitis and cutaneous adverse food reactions. Vet Dermatol 2007; 18:390-391.
  • 13. Picco F, Zini E, Nett C, Naegeli C, Bigler B, Rufenacht S, et al. A prospective study on canine atopic dermatitis and food-induced allergic dermatitis in Switzerland. Vet Dermatol 2008; 19:150-155.
  • 14. Zur G, Ihrke PJ, White SD, et al. Canine atopic dermatitis: a retrospective study of 266 cases examined at the University of California, Davis, 1992- 1998. Part I. Clinical features and allergy testing results. Vet Dermatol 2002; 13:89-102.
  • 15. Griffin CE, DeBoer DJ. The ACVD task force on canine atopic dermatitis (XIV):clinical manifestations of canine atopic dermatitis. Vet Immunol Immunopathol 2001; 81:255-269.
  • 16. Olivry T, Saridomichelakis M. International Committee on Atopic Diseases of A. Evidence-based guidelines for anti-allergic drug withdrawal times before allergen-specific intradermal and IgE serological tests in dogs. Vet Dermatol 2013; 24:225-249.
  • 17. Hensel P, Austel M, Wooley RE, et al. In vitro and in vivo evaluation of a potentiated miconazole aural solution in chronic Malassezia otitis externa in dogs. Vet Dermatol 2009; 20:429-434.
  • 18. Marsella R, Sousa CA, Gonzales AJ, et al. Current understanding of the pathophysiologic mechanisms of canine atopic dermatitis. J Am Vet Med Assoc 2012; 241:194-207.
  • 19. Hillier A, DeBoer DJ. The ACVD task force on canine atopic dermatitis (XVII): intradermal testing. Vet Immunol Immunopathol 2001; 81:289-304.
  • 20. Hensel P, Austel M, Medleau L, et al. Determination of threshold concentrations of allergens and evaluation of two different histamine concentrations in canine intradermal testing. Vet Dermatol 2004; 15:304-308.
  • 21. Bauer CL, Hensel P, Austel M, et al. Determination of irritant threshold concentrations to weeds, trees and grasses through serial dilutions in intradermal testing on healthy clinically non allergic dogs. Vet Dermatol 2010; 21:192-197.
  • 22. Suto A, Suto Y, Onohaga N, et al. Food allergens inducing a lymphocyte-mediated immunological reaction in canine atopi-like dermatitis. J Vet Med Sci 2015; 77:251-254.
  • 23. Ownby DR. Clinical significance of immunoglobulin E. In : Middleton EJ, Reed CE, Ellis EF (eds), Allergy: Principles and Practice. 5th ed. Mosby, St. Louis, 1998; pp 770-782.
  • 24. Foster AP, Littlewood JD, Webb P, et al. Comparison of intradermal and serum testing for allergenspecific IgE using a Fc epsilon RI alpha-based assay in atopic dogs in the UK. Vet Immunol Immunopathol 2003; 93:51-60.
  • 25. Park S, Ohya F, Yamashita K, et al. Comparison of response to immunotherapy by intradermal skin test and antigen-specific IgE in canine atopy. J Vet Med Sci 2000; 62:983-988.
  • 26. Hillier A, Griffin CE. The ACVD task force on canine atopic dermatitis (X): is there a relationship between canine atopic dermatitis and cutaneous adverse food reactions? Vet Immunol Immunopathol 2001; 81:227-231.
  • 27. Cunha VE, Faccini JL. Use of histamine phosphate for the interpretation of intradermal skin tests in dogs. Vet Rec 2009; 165:723-724.
  • 28. Temizel EM, Aytug N. Intradermal Testing Results and Clinical Features in Dogs with Atopic Dermatitis in Turkey. J Biol Environ Sci 2011; 5:87-89.
  • 29. Temizel EM, Cihan H, Akhtardanesh B, et al. Effect of prednisolone and cetirizine on D. farinae and histamine-induced wheal and flare response in healthy dogs. Tierärztliche Praxis K: Kleintiere/Heimtiere 2011; 39:25-30.
  • 30. Saevik BK, Ulstein TL, Larsen HJ. Evaluation of a commercially available enzyme-linked immunosorbent assay for the detection of allergen-specific IgE antibodies in dogs. Res Vet Sci 2003; 74:37-45.
  • 31. Plant JD, Neradelik MB, Polissar NL, et al. Agreement between allergen-specific IgE assays and ensuing immunotherapy recommendations from four commercial laboratories in the USA. Vet Dermatol 2014; 25:15-16.
  • 32. Marsella R, Kunkle GA, Vaughn DM, et al. Doubleblind pilot study on the effects of ketoconazole on intradermal skin test and leukotriene C4 concentration in the skin of atopic dogs. Vet Dermatol 1997; 8:3-10.
  • 33. Goldman C, Rosser Jr E, Petersen A, et al. Investigation on the effects of cyclosporine (Atopica) on intradermal test reactivity and allergen specific immunoglobulin (IgE) serology in atopic dogs. Vet Dermatol 2010; 21:393-399.
  • 34. Martin DD, Martin AL. Pain management and anesthesia in veterinary dermatology. Vet Clin North Am Small Anim Pract 2006; 36:1-14.
  • 35. Kennis RA, Robertson SA, Rosser Jr EJ, et al. Effects of propofol anesthesia on intradermally injected histamine phosphate in clinically normal dogs. Am J Vet Res 1998; 59:7-9.
  • 36. Graham LF, Torres SM, Jessen CR, et al. Effects of propofol-induced sedation on intradermal test reactions in dogs with atopic dermatitis. Vet Dermatol 2003; 14:167-176.

New Trends in the Diagnosis and Allergen Determination of Canine Atopic Dermatitis

Yıl 2018, Cilt: 27 Sayı: 2, 176 - 181, 01.07.2018

Öz

Canine atopic dermatitis (AD) is a common, genetically
predisposed, inflammatory and pruritic skin disease.
The variation in clinical presentations, due to genetic
factors, the extent of the lesions, the stage of the disease, secondary infections, as well as resemblance to
other non-atopic related skin diseases, can complicate
the diagnosis of canine AD. In conclusion, the diagnosis
of canine AD is based on meeting clinical criteria and
ruling out other possible causes with similar clinical
signs. Once the clinical diagnosis of canine AD is made,
allergy testing can be performed to identify potential
causative allergens for allergen-specific immunotherapy

Kaynakça

  • 1. Halliwell R. Revised nomenclature for veterinary allergy. Vet Immunol Immunopathol 2006; 114:207 -208.
  • 2. DeBoer DJ, Hillier A. The ACVD task force on canine atopic dermatitis (XV): fundamental concepts in clinical diagnosis. Vet Immunol Immunopathol 2001; 81:271-276.
  • 3. Nuttall T. The genomics revolution: will canine atopic dermatitis be predictable and preventable? Vet Dermatol 2013; 24:13-14.
  • 4. Aytuğ N, Kanat Ö, Kömürcü B. Köpeklerin atopik dermatitisi. Turkiye Klinikleri J Vet Sci Intern MedSpecial Topics 2017; 3:202-208.
  • 5. Olivry T, DeBoer DJ, Favrot C, et al. Treatment of canine atopic dermatitis: 2015 updated guidelines from the International Committee on Allergic Diseases of Animals (ICADA). BMC Veterinary Research 2015; 11: 210.
  • 6. Favrot C, Steffan J, Seewald W, et al. A prospective study on the clinical features of chronic canine atopic dermatitis and its diagnosis. Vet Dermatol 2010; 21:23-31.
  • 7. Willemse TA. Atopic dermatitis: a review and reconsideration of diagnostic criteria. JSAP 1986; 27: 771 -778.
  • 8. Pre´laud P, Guague`re E, Alhaidari Z, et al. Reevaluation of diagnostic criteria of canine atopic dermatitis. Rev Med Vet 1998; 149:1057-1064.
  • 9. Hensel P, Santoro D, Favrot C, et al. Canine atopic dermatitis: detailed guidelines for diagnosis and allergen identification. BMC Veterinary Research 2015; 11: 1-13.
  • 10. Bruet V, Bourdeau PJ, Roussel A, Imparato L, Desfontis JC. Characterization of pruritus in canine atopic dermatitis, flea bite hypersensitivity and flea infestation and its role in diagnosis. Vet Dermatol 2012; 23:487-493.
  • 11. Miller WH, Griffin CE. Campbell KL. In: Small Animal Dermatology. 7th ed. St.Louis: WB Elsevier. 2013; p 363-431.
  • 12. Olivry T, Deboer DJ, Prelaud P, Bensignor E. International Task Force on Canine Atopic Dermatitis. Food for thought: pondering the relationship between canine atopic dermatitis and cutaneous adverse food reactions. Vet Dermatol 2007; 18:390-391.
  • 13. Picco F, Zini E, Nett C, Naegeli C, Bigler B, Rufenacht S, et al. A prospective study on canine atopic dermatitis and food-induced allergic dermatitis in Switzerland. Vet Dermatol 2008; 19:150-155.
  • 14. Zur G, Ihrke PJ, White SD, et al. Canine atopic dermatitis: a retrospective study of 266 cases examined at the University of California, Davis, 1992- 1998. Part I. Clinical features and allergy testing results. Vet Dermatol 2002; 13:89-102.
  • 15. Griffin CE, DeBoer DJ. The ACVD task force on canine atopic dermatitis (XIV):clinical manifestations of canine atopic dermatitis. Vet Immunol Immunopathol 2001; 81:255-269.
  • 16. Olivry T, Saridomichelakis M. International Committee on Atopic Diseases of A. Evidence-based guidelines for anti-allergic drug withdrawal times before allergen-specific intradermal and IgE serological tests in dogs. Vet Dermatol 2013; 24:225-249.
  • 17. Hensel P, Austel M, Wooley RE, et al. In vitro and in vivo evaluation of a potentiated miconazole aural solution in chronic Malassezia otitis externa in dogs. Vet Dermatol 2009; 20:429-434.
  • 18. Marsella R, Sousa CA, Gonzales AJ, et al. Current understanding of the pathophysiologic mechanisms of canine atopic dermatitis. J Am Vet Med Assoc 2012; 241:194-207.
  • 19. Hillier A, DeBoer DJ. The ACVD task force on canine atopic dermatitis (XVII): intradermal testing. Vet Immunol Immunopathol 2001; 81:289-304.
  • 20. Hensel P, Austel M, Medleau L, et al. Determination of threshold concentrations of allergens and evaluation of two different histamine concentrations in canine intradermal testing. Vet Dermatol 2004; 15:304-308.
  • 21. Bauer CL, Hensel P, Austel M, et al. Determination of irritant threshold concentrations to weeds, trees and grasses through serial dilutions in intradermal testing on healthy clinically non allergic dogs. Vet Dermatol 2010; 21:192-197.
  • 22. Suto A, Suto Y, Onohaga N, et al. Food allergens inducing a lymphocyte-mediated immunological reaction in canine atopi-like dermatitis. J Vet Med Sci 2015; 77:251-254.
  • 23. Ownby DR. Clinical significance of immunoglobulin E. In : Middleton EJ, Reed CE, Ellis EF (eds), Allergy: Principles and Practice. 5th ed. Mosby, St. Louis, 1998; pp 770-782.
  • 24. Foster AP, Littlewood JD, Webb P, et al. Comparison of intradermal and serum testing for allergenspecific IgE using a Fc epsilon RI alpha-based assay in atopic dogs in the UK. Vet Immunol Immunopathol 2003; 93:51-60.
  • 25. Park S, Ohya F, Yamashita K, et al. Comparison of response to immunotherapy by intradermal skin test and antigen-specific IgE in canine atopy. J Vet Med Sci 2000; 62:983-988.
  • 26. Hillier A, Griffin CE. The ACVD task force on canine atopic dermatitis (X): is there a relationship between canine atopic dermatitis and cutaneous adverse food reactions? Vet Immunol Immunopathol 2001; 81:227-231.
  • 27. Cunha VE, Faccini JL. Use of histamine phosphate for the interpretation of intradermal skin tests in dogs. Vet Rec 2009; 165:723-724.
  • 28. Temizel EM, Aytug N. Intradermal Testing Results and Clinical Features in Dogs with Atopic Dermatitis in Turkey. J Biol Environ Sci 2011; 5:87-89.
  • 29. Temizel EM, Cihan H, Akhtardanesh B, et al. Effect of prednisolone and cetirizine on D. farinae and histamine-induced wheal and flare response in healthy dogs. Tierärztliche Praxis K: Kleintiere/Heimtiere 2011; 39:25-30.
  • 30. Saevik BK, Ulstein TL, Larsen HJ. Evaluation of a commercially available enzyme-linked immunosorbent assay for the detection of allergen-specific IgE antibodies in dogs. Res Vet Sci 2003; 74:37-45.
  • 31. Plant JD, Neradelik MB, Polissar NL, et al. Agreement between allergen-specific IgE assays and ensuing immunotherapy recommendations from four commercial laboratories in the USA. Vet Dermatol 2014; 25:15-16.
  • 32. Marsella R, Kunkle GA, Vaughn DM, et al. Doubleblind pilot study on the effects of ketoconazole on intradermal skin test and leukotriene C4 concentration in the skin of atopic dogs. Vet Dermatol 1997; 8:3-10.
  • 33. Goldman C, Rosser Jr E, Petersen A, et al. Investigation on the effects of cyclosporine (Atopica) on intradermal test reactivity and allergen specific immunoglobulin (IgE) serology in atopic dogs. Vet Dermatol 2010; 21:393-399.
  • 34. Martin DD, Martin AL. Pain management and anesthesia in veterinary dermatology. Vet Clin North Am Small Anim Pract 2006; 36:1-14.
  • 35. Kennis RA, Robertson SA, Rosser Jr EJ, et al. Effects of propofol anesthesia on intradermally injected histamine phosphate in clinically normal dogs. Am J Vet Res 1998; 59:7-9.
  • 36. Graham LF, Torres SM, Jessen CR, et al. Effects of propofol-induced sedation on intradermal test reactions in dogs with atopic dermatitis. Vet Dermatol 2003; 14:167-176.
Toplam 36 adet kaynakça vardır.

Ayrıntılar

Diğer ID JA33ZM67UR
Bölüm Araştırma Makalesi
Yazarlar

Öykü Barılı

Didem Pekmezci Bu kişi benim

Yayımlanma Tarihi 1 Temmuz 2018
Gönderilme Tarihi 1 Temmuz 2018
Yayımlandığı Sayı Yıl 2018 Cilt: 27 Sayı: 2

Kaynak Göster

APA Barılı, Ö., & Pekmezci, D. (2018). KÖPEK ATOPİK DERMATİTİSİNDE TEŞHİS VE ALERJEN TAYİNİNDEKİ GÜNCEL YAKLAŞIMLAR. Sağlık Bilimleri Dergisi, 27(2), 176-181.
AMA Barılı Ö, Pekmezci D. KÖPEK ATOPİK DERMATİTİSİNDE TEŞHİS VE ALERJEN TAYİNİNDEKİ GÜNCEL YAKLAŞIMLAR. JHS. Temmuz 2018;27(2):176-181.
Chicago Barılı, Öykü, ve Didem Pekmezci. “KÖPEK ATOPİK DERMATİTİSİNDE TEŞHİS VE ALERJEN TAYİNİNDEKİ GÜNCEL YAKLAŞIMLAR”. Sağlık Bilimleri Dergisi 27, sy. 2 (Temmuz 2018): 176-81.
EndNote Barılı Ö, Pekmezci D (01 Temmuz 2018) KÖPEK ATOPİK DERMATİTİSİNDE TEŞHİS VE ALERJEN TAYİNİNDEKİ GÜNCEL YAKLAŞIMLAR. Sağlık Bilimleri Dergisi 27 2 176–181.
IEEE Ö. Barılı ve D. Pekmezci, “KÖPEK ATOPİK DERMATİTİSİNDE TEŞHİS VE ALERJEN TAYİNİNDEKİ GÜNCEL YAKLAŞIMLAR”, JHS, c. 27, sy. 2, ss. 176–181, 2018.
ISNAD Barılı, Öykü - Pekmezci, Didem. “KÖPEK ATOPİK DERMATİTİSİNDE TEŞHİS VE ALERJEN TAYİNİNDEKİ GÜNCEL YAKLAŞIMLAR”. Sağlık Bilimleri Dergisi 27/2 (Temmuz 2018), 176-181.
JAMA Barılı Ö, Pekmezci D. KÖPEK ATOPİK DERMATİTİSİNDE TEŞHİS VE ALERJEN TAYİNİNDEKİ GÜNCEL YAKLAŞIMLAR. JHS. 2018;27:176–181.
MLA Barılı, Öykü ve Didem Pekmezci. “KÖPEK ATOPİK DERMATİTİSİNDE TEŞHİS VE ALERJEN TAYİNİNDEKİ GÜNCEL YAKLAŞIMLAR”. Sağlık Bilimleri Dergisi, c. 27, sy. 2, 2018, ss. 176-81.
Vancouver Barılı Ö, Pekmezci D. KÖPEK ATOPİK DERMATİTİSİNDE TEŞHİS VE ALERJEN TAYİNİNDEKİ GÜNCEL YAKLAŞIMLAR. JHS. 2018;27(2):176-81.